Compile Data Set for Download or QSAR
Report error Found 44 Enz. Inhib. hit(s) with all data for entry = 50038507
TargetThrombopoietin receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50219625BDBM50219625(N-(4-(2-fluoro-3-(trifluoromethoxy)phenyl)thiazol-...)
Affinity DataEC50:  32nMAssay Description:Agonist activity at TPO receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50377376BDBM50377376(CHEMBL408853)
Affinity DataEC50:  32nMAssay Description:Agonist activity at TPO receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50219679BDBM50219679(N-(4-(2,4-difluoro-3-(trifluoromethyl)phenyl)thiaz...)
Affinity DataEC50:  33nMAssay Description:Agonist activity at TPO receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50377375BDBM50377375(CHEMBL263109)
Affinity DataEC50:  57nMAssay Description:Agonist activity at TPO receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50219607BDBM50219607(N-(4-(2-fluoro-3-(trifluoromethyl)phenyl)thiazol-2...)
Affinity DataEC50:  60nMAssay Description:Agonist activity at TPO receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50219712BDBM50219712(4-(pyrimidin-4-ylamino)-N-(4-(2,3,4-trifluoropheny...)
Affinity DataEC50:  84nMAssay Description:Agonist activity at TPO receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50219646BDBM50219646(N-(4-(2,3-difluoro-4-(trifluoromethyl)phenyl)thiaz...)
Affinity DataEC50:  87nMAssay Description:Agonist activity at TPO receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50377369BDBM50377369(CHEMBL405683)
Affinity DataEC50:  89nMAssay Description:Agonist activity at TPO receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50219616BDBM50219616(N-(4-(3-bromo-2-fluorophenyl)thiazol-2-yl)-4-(pyri...)
Affinity DataEC50:  100nMAssay Description:Agonist activity at TPO receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50377370BDBM50377370(CHEMBL260846)
Affinity DataEC50:  100nMAssay Description:Agonist activity at TPO receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50219638BDBM50219638(N-(4-(4-fluoro-3-(trifluoromethyl)phenyl)thiazol-2...)
Affinity DataEC50:  100nMAssay Description:Agonist activity at TPO receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50219671BDBM50219671(4-(pyrimidin-4-ylamino)-N-(6-(trifluoromethyl)-4H-...)
Affinity DataEC50:  140nMAssay Description:Agonist activity at TPO receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50219658BDBM50219658(N-(4-(2,4-difluorophenyl)thiazol-2-yl)-4-(pyrimidi...)
Affinity DataEC50:  170nMAssay Description:Agonist activity at TPO receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50377368BDBM50377368(CHEMBL258532)
Affinity DataEC50:  180nMAssay Description:Agonist activity at TPO receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50219632BDBM50219632(N-(4-(4-chloro-2-fluorophenyl)thiazol-2-yl)-4-(pyr...)
Affinity DataEC50:  230nMAssay Description:Agonist activity at TPO receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50377374BDBM50377374(CHEMBL405478)
Affinity DataEC50:  260nMAssay Description:Agonist activity at TPO receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50219707BDBM50219707(N-(4-(2-fluoro-4-(trifluoromethyl)phenyl)thiazol-2...)
Affinity DataEC50:  260nMAssay Description:Agonist activity at TPO receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50219631BDBM50219631(4-(pyrimidin-4-ylamino)-N-(4-(3-(trifluoromethoxy)...)
Affinity DataEC50:  280nMAssay Description:Agonist activity at TPO receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50219680BDBM50219680(N-(4-(3-fluoro-4-(trifluoromethyl)phenyl)thiazol-2...)
Affinity DataEC50:  290nMAssay Description:Agonist activity at TPO receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50219656BDBM50219656(N-(4-(3,4-difluorophenyl)thiazol-2-yl)-4-(pyrimidi...)
Affinity DataEC50:  400nMAssay Description:Agonist activity at TPO receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50219651BDBM50219651(4-(pyrimidin-4-ylamino)-N-(4-(3-(trifluoromethyl)p...)
Affinity DataEC50:  420nMAssay Description:Agonist activity at TPO receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50219612BDBM50219612(N-(4-(2,3-difluorophenyl)thiazol-2-yl)-4-(pyrimidi...)
Affinity DataEC50:  420nMAssay Description:Agonist activity at TPO receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50219665BDBM50219665(4-(pyrimidin-4-ylamino)-N-(4-(4-(trifluoromethyl)p...)
Affinity DataEC50:  490nMAssay Description:Agonist activity at TPO receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50219630BDBM50219630(N-(4-(2,4-dichlorophenyl)thiazol-2-yl)-4-(pyrimidi...)
Affinity DataEC50:  510nMAssay Description:Agonist activity at TPO receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50377381BDBM50377381(CHEMBL409504)
Affinity DataEC50:  520nMAssay Description:Agonist activity at TPO receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50377379BDBM50377379(CHEMBL409092)
Affinity DataEC50:  530nMAssay Description:Agonist activity at TPO receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50377371BDBM50377371(CHEMBL405203)
Affinity DataEC50:  540nMAssay Description:Agonist activity at TPO receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50219642BDBM50219642(N-(4-(4-chlorophenyl)thiazol-2-yl)-4-(pyrimidin-4-...)
Affinity DataEC50:  570nMAssay Description:Agonist activity at TPO receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50219608BDBM50219608(N-(4-(3-chloro-2-fluorophenyl)thiazol-2-yl)-4-(pyr...)
Affinity DataEC50:  610nMAssay Description:Agonist activity at TPO receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50219717BDBM50219717(N-(4-(3-bromophenyl)thiazol-2-yl)-4-(pyrimidin-4-y...)
Affinity DataEC50:  640nMAssay Description:Agonist activity at TPO receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50377372BDBM50377372(CHEMBL262855)
Affinity DataEC50:  700nMAssay Description:Agonist activity at TPO receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50219708BDBM50219708(N-(4-(2,3-dichlorophenyl)thiazol-2-yl)-4-(pyrimidi...)
Affinity DataEC50:  1.30E+3nMAssay Description:Agonist activity at TPO receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50377380BDBM50377380(CHEMBL260089)
Affinity DataEC50:  1.50E+3nMAssay Description:Agonist activity at TPO receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50219709BDBM50219709(N-(4-(4-fluorophenyl)thiazol-2-yl)-4-(pyrimidin-4-...)
Affinity DataEC50:  2.60E+3nMAssay Description:Agonist activity at TPO receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50219684BDBM50219684(N-(4-(3-chlorophenyl)thiazol-2-yl)-4-(pyrimidin-4-...)
Affinity DataEC50:  3.00E+3nMAssay Description:Agonist activity at TPO receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50219693BDBM50219693(N-(4-phenylthiazol-2-yl)-4-(pyrimidin-4-ylamino)be...)
Affinity DataEC50:  3.40E+3nMAssay Description:Agonist activity at TPO receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50377373BDBM50377373(CHEMBL261539)
Affinity DataEC50:  5.20E+3nMAssay Description:Agonist activity at TPO receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50377378BDBM50377378(CHEMBL261023)
Affinity DataEC50:  6.80E+3nMAssay Description:Agonist activity at TPO receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50219678BDBM50219678(N-(4-(2-fluorophenyl)thiazol-2-yl)-4-(pyrimidin-4-...)
Affinity DataEC50:  6.80E+3nMAssay Description:Agonist activity at TPO receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50219636BDBM50219636(N-(4-(2-chlorophenyl)thiazol-2-yl)-4-(pyrimidin-4-...)
Affinity DataEC50:  9.00E+3nMAssay Description:Agonist activity at TPO receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50219663BDBM50219663(N-(4-(2,6-difluorophenyl)thiazol-2-yl)-4-(pyrimidi...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at TPO receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50377377BDBM50377377(CHEMBL412807)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at TPO receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50219647BDBM50219647(4-(pyrimidin-4-ylamino)-N-(4-(2-(trifluoromethyl)p...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at TPO receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50219690BDBM50219690(N-(4-(3-fluorophenyl)thiazol-2-yl)-4-(pyrimidin-4-...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at TPO receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed