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Found 62 Enz. Inhib. hit(s) with all data for entry = 50038516
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50377576(CHEMBL401596)
Affinity DataIC50:  3nMAssay Description:Inhibition of [3H]5-HT uptake at human recombinant 5HT transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50377579(CHEMBL403078)
Affinity DataIC50:  4nMAssay Description:Inhibition of [3H]5-HT uptake at human recombinant 5HT transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50377573(CHEMBL256136)
Affinity DataIC50:  4nMAssay Description:Inhibition of [3H]5-HT uptake at human recombinant 5HT transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50377586(CHEMBL257593)
Affinity DataIC50:  6nMAssay Description:Inhibition of [3H]5-HT uptake at human recombinant 5HT transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50377574(CHEMBL256970)
Affinity DataIC50:  6nMAssay Description:Inhibition of [3H]5-HT uptake at human recombinant 5HT transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50377575(CHEMBL256137)
Affinity DataIC50:  6nMAssay Description:Inhibition of [3H]5-HT uptake at human recombinant 5HT transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50203945((S)-N-(2,3-dimethylbenzyl)-N-(tetrahydro-2H-pyran-...)
Affinity DataIC50:  7nMAssay Description:Inhibition of [3H]NA uptake at human recombinant NA transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50371626(CHEMBL402345)
Affinity DataIC50:  7nMAssay Description:Inhibition of [3H]5-HT uptake at human recombinant 5HT transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50377569(CHEMBL260036)
Affinity DataIC50:  8nMAssay Description:Inhibition of [3H]5-HT uptake at human recombinant 5HT transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50203945((S)-N-(2,3-dimethylbenzyl)-N-(tetrahydro-2H-pyran-...)
Affinity DataIC50:  9nMAssay Description:Inhibition of [3H]5-HT uptake at human recombinant 5HT transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50377572(CHEMBL402371)
Affinity DataIC50:  10nMAssay Description:Inhibition of [3H]5-HT uptake at human recombinant 5HT transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50377585(CHEMBL402000)
Affinity DataIC50:  11nMAssay Description:Inhibition of [3H]5-HT uptake at human recombinant 5HT transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50377578(CHEMBL403080)
Affinity DataIC50:  13nMAssay Description:Inhibition of [3H]5-HT uptake at human recombinant 5HT transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50188098((R)-1-(2-(2-ethoxyphenyl)-1-phenylethyl)piperazine...)
Affinity DataIC50:  14nMAssay Description:Inhibition of [3H]5-HT uptake at human recombinant 5HT transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50377580(CHEMBL258449)
Affinity DataIC50:  14nMAssay Description:Inhibition of [3H]5-HT uptake at human recombinant 5HT transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50377584(CHEMBL256511)
Affinity DataIC50:  14nMAssay Description:Inhibition of [3H]5-HT uptake at human recombinant 5HT transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50188098((R)-1-(2-(2-ethoxyphenyl)-1-phenylethyl)piperazine...)
Affinity DataIC50:  18nMAssay Description:Inhibition of [3H]NA uptake at human recombinant NA transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50377585(CHEMBL402000)
Affinity DataIC50:  18nMAssay Description:Inhibition of [3H]NA uptake at human recombinant NA transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50377571(CHEMBL260038)
Affinity DataIC50:  18nMAssay Description:Inhibition of [3H]5-HT uptake at human recombinant 5HT transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50375715(CHEMBL256293)
Affinity DataIC50:  19nMAssay Description:Inhibition of [3H]5-HT uptake at human recombinant 5HT transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50375708(CHEMBL403251)
Affinity DataIC50:  20nMAssay Description:Inhibition of [3H]5-HT uptake at human recombinant 5HT transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50375708(CHEMBL403251)
Affinity DataIC50:  22nMAssay Description:Inhibition of [3H]NA uptake at human recombinant NA transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50377583(CHEMBL256135)
Affinity DataIC50:  23nMAssay Description:Inhibition of [3H]5-HT uptake at human recombinant 5HT transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50377581(CHEMBL260037)
Affinity DataIC50:  24nMAssay Description:Inhibition of [3H]5-HT uptake at human recombinant 5HT transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50377569(CHEMBL260036)
Affinity DataIC50:  25nMAssay Description:Inhibition of [3H]NA uptake at human recombinant NA transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50377574(CHEMBL256970)
Affinity DataIC50:  26nMAssay Description:Inhibition of [3H]NA uptake at human recombinant NA transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50377578(CHEMBL403080)
Affinity DataIC50:  26nMAssay Description:Inhibition of [3H]NA uptake at human recombinant NA transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50377573(CHEMBL256136)
Affinity DataIC50:  26nMAssay Description:Inhibition of [3H]NA uptake at human recombinant NA transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50375715(CHEMBL256293)
Affinity DataIC50:  30nMAssay Description:Inhibition of [3H]NA uptake at human recombinant NA transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50371626(CHEMBL402345)
Affinity DataIC50:  32nMAssay Description:Inhibition of [3H]NA uptake at human recombinant NA transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50377576(CHEMBL401596)
Affinity DataIC50:  36nMAssay Description:Inhibition of [3H]NA uptake at human recombinant NA transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50377572(CHEMBL402371)
Affinity DataIC50:  38nMAssay Description:Inhibition of [3H]NA uptake at human recombinant NA transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50377570(CHEMBL259136)
Affinity DataIC50:  39nMAssay Description:Inhibition of [3H]5-HT uptake at human recombinant 5HT transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50377577(CHEMBL257592)
Affinity DataIC50:  46nMAssay Description:Inhibition of [3H]5-HT uptake at human recombinant 5HT transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50377586(CHEMBL257593)
Affinity DataIC50:  47nMAssay Description:Inhibition of [3H]NA uptake at human recombinant NA transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50377575(CHEMBL256137)
Affinity DataIC50:  51nMAssay Description:Inhibition of [3H]NA uptake at human recombinant NA transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50377579(CHEMBL403078)
Affinity DataIC50:  83nMAssay Description:Inhibition of [3H]NA uptake at human recombinant NA transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50377583(CHEMBL256135)
Affinity DataIC50:  85nMAssay Description:Inhibition of [3H]NA uptake at human recombinant NA transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50377577(CHEMBL257592)
Affinity DataIC50:  86nMAssay Description:Inhibition of [3H]NA uptake at human recombinant NA transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50377570(CHEMBL259136)
Affinity DataIC50:  159nMAssay Description:Inhibition of [3H]NA uptake at human recombinant NA transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50377582(CHEMBL260039)
Affinity DataIC50:  231nMAssay Description:Inhibition of [3H]5-HT uptake at human recombinant 5HT transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50377584(CHEMBL256511)
Affinity DataIC50:  246nMAssay Description:Inhibition of [3H]NA uptake at human recombinant NA transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50377571(CHEMBL260038)
Affinity DataIC50:  257nMAssay Description:Inhibition of [3H]NA uptake at human recombinant NA transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50377580(CHEMBL258449)
Affinity DataIC50:  282nMAssay Description:Inhibition of [3H]NA uptake at human recombinant NA transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50377581(CHEMBL260037)
Affinity DataIC50:  394nMAssay Description:Inhibition of [3H]NA uptake at human recombinant NA transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50377582(CHEMBL260039)
Affinity DataIC50: >400nMAssay Description:Inhibition of [3H]NA uptake at human recombinant NA transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50203945((S)-N-(2,3-dimethylbenzyl)-N-(tetrahydro-2H-pyran-...)
Affinity DataIC50:  727nMAssay Description:Inhibition of [3H]DA uptake at human recombinant DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50377574(CHEMBL256970)
Affinity DataIC50:  1.68E+3nMAssay Description:Inhibition of [3H]DA uptake at human recombinant DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50377573(CHEMBL256136)
Affinity DataIC50:  1.97E+3nMAssay Description:Inhibition of [3H]DA uptake at human recombinant DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50377569(CHEMBL260036)
Affinity DataIC50:  2.43E+3nMAssay Description:Inhibition of [3H]DA uptake at human recombinant DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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