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Report error Found 71 Enz. Inhib. hit(s) with all data for entry = 50041586
TargetP2X purinoceptor 7(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50412149(CHEMBL497967)
Affinity DataIC50:  5.01nMAssay Description:Antagonist activity at human recombinant P2X7 receptor expressed in differentiated human THP1 cells assessed as inhibition of benzoyl-ATP-induced IL1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50412149(CHEMBL497967)
Affinity DataIC50:  10.2nMAssay Description:Antagonist activity at human recombinant P2X7 receptor expressed in human 1321N1 cells assessed as benzoyl-ATP-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50412145(CHEMBL523873)
Affinity DataIC50:  10.2nMAssay Description:Antagonist activity at human recombinant P2X7 receptor expressed in human 1321N1 cells assessed as benzoyl-ATP-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50412155(CHEMBL496299)
Affinity DataIC50:  11.5nMAssay Description:Antagonist activity at human recombinant P2X7 receptor expressed in human 1321N1 cells assessed as benzoyl-ATP-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50412162(CHEMBL522067)
Affinity DataIC50:  11.8nMAssay Description:Antagonist activity at human recombinant P2X7 receptor expressed in human 1321N1 cells assessed as benzoyl-ATP-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50412137(CHEMBL523548)
Affinity DataIC50:  18.6nMAssay Description:Antagonist activity at human recombinant P2X7 receptor expressed in human 1321N1 cells assessed as benzoyl-ATP-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50412144(CHEMBL494625)
Affinity DataIC50:  22.9nMAssay Description:Antagonist activity at human recombinant P2X7 receptor expressed in human 1321N1 cells assessed as benzoyl-ATP-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50412147(CHEMBL451692)
Affinity DataIC50:  27.5nMAssay Description:Antagonist activity at human recombinant P2X7 receptor expressed in human 1321N1 cells assessed as benzoyl-ATP-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50412138(CHEMBL451353)
Affinity DataIC50:  27.5nMAssay Description:Antagonist activity at human recombinant P2X7 receptor expressed in human 1321N1 cells assessed as benzoyl-ATP-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50412162(CHEMBL522067)
Affinity DataIC50:  28.2nMAssay Description:Antagonist activity at rat recombinant P2X7 receptor expressed in human 1321N1 cells assessed as benzoyl-ATP-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50412137(CHEMBL523548)
Affinity DataIC50:  31.6nMAssay Description:Antagonist activity at rat recombinant P2X7 receptor expressed in human 1321N1 cells assessed as benzoyl-ATP-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50412150(CHEMBL525541)
Affinity DataIC50:  33.9nMAssay Description:Antagonist activity at human recombinant P2X7 receptor expressed in human 1321N1 cells assessed as benzoyl-ATP-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50412155(CHEMBL496299)
Affinity DataIC50:  33.9nMAssay Description:Antagonist activity at rat recombinant P2X7 receptor expressed in human 1321N1 cells assessed as benzoyl-ATP-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50412164(CHEMBL496085)
Affinity DataIC50:  33.9nMAssay Description:Antagonist activity at human recombinant P2X7 receptor expressed in human 1321N1 cells assessed as benzoyl-ATP-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50412154(CHEMBL523908)
Affinity DataIC50:  34.7nMAssay Description:Antagonist activity at human recombinant P2X7 receptor expressed in human 1321N1 cells assessed as benzoyl-ATP-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50412145(CHEMBL523873)
Affinity DataIC50:  35.5nMAssay Description:Antagonist activity at rat recombinant P2X7 receptor expressed in human 1321N1 cells assessed as benzoyl-ATP-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50412165(CHEMBL509756)
Affinity DataIC50:  38.9nMAssay Description:Antagonist activity at human recombinant P2X7 receptor expressed in human 1321N1 cells assessed as benzoyl-ATP-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50412158(CHEMBL505953)
Affinity DataIC50:  39.8nMAssay Description:Antagonist activity at human recombinant P2X7 receptor expressed in human 1321N1 cells assessed as benzoyl-ATP-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50412149(CHEMBL497967)
Affinity DataIC50:  44.7nMAssay Description:Antagonist activity at rat recombinant P2X7 receptor expressed in human 1321N1 cells assessed as benzoyl-ATP-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50412164(CHEMBL496085)
Affinity DataIC50:  49.0nMAssay Description:Antagonist activity at rat recombinant P2X7 receptor expressed in human 1321N1 cells assessed as benzoyl-ATP-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50412148(CHEMBL523540)
Affinity DataIC50:  51.3nMAssay Description:Antagonist activity at human recombinant P2X7 receptor expressed in human 1321N1 cells assessed as benzoyl-ATP-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50412154(CHEMBL523908)
Affinity DataIC50:  51.3nMAssay Description:Antagonist activity at rat recombinant P2X7 receptor expressed in human 1321N1 cells assessed as benzoyl-ATP-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50412142(CHEMBL493802)
Affinity DataIC50:  51.3nMAssay Description:Antagonist activity at rat recombinant P2X7 receptor expressed in human 1321N1 cells assessed as benzoyl-ATP-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50412147(CHEMBL451692)
Affinity DataIC50:  52.5nMAssay Description:Antagonist activity at rat recombinant P2X7 receptor expressed in human 1321N1 cells assessed as benzoyl-ATP-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50412142(CHEMBL493802)
Affinity DataIC50:  52.5nMAssay Description:Antagonist activity at human recombinant P2X7 receptor expressed in human 1321N1 cells assessed as benzoyl-ATP-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50412160(CHEMBL496499)
Affinity DataIC50:  57.5nMAssay Description:Antagonist activity at human recombinant P2X7 receptor expressed in human 1321N1 cells assessed as benzoyl-ATP-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50412146(CHEMBL521858)
Affinity DataIC50:  57.5nMAssay Description:Antagonist activity at human recombinant P2X7 receptor expressed in human 1321N1 cells assessed as benzoyl-ATP-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50412139(CHEMBL523385)
Affinity DataIC50:  70.8nMAssay Description:Antagonist activity at human recombinant P2X7 receptor expressed in human 1321N1 cells assessed as benzoyl-ATP-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50412166(CHEMBL496088)
Affinity DataIC50:  70.8nMAssay Description:Antagonist activity at human recombinant P2X7 receptor expressed in human 1321N1 cells assessed as benzoyl-ATP-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50412159(CHEMBL522068)
Affinity DataIC50:  110nMAssay Description:Antagonist activity at human recombinant P2X7 receptor expressed in human 1321N1 cells assessed as benzoyl-ATP-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50412138(CHEMBL451353)
Affinity DataIC50:  123nMAssay Description:Antagonist activity at rat recombinant P2X7 receptor expressed in human 1321N1 cells assessed as benzoyl-ATP-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50412163(CHEMBL496087)
Affinity DataIC50:  132nMAssay Description:Antagonist activity at human recombinant P2X7 receptor expressed in human 1321N1 cells assessed as benzoyl-ATP-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50412160(CHEMBL496499)
Affinity DataIC50:  135nMAssay Description:Antagonist activity at rat recombinant P2X7 receptor expressed in human 1321N1 cells assessed as benzoyl-ATP-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50412140(CHEMBL494815)
Affinity DataIC50:  141nMAssay Description:Antagonist activity at human recombinant P2X7 receptor expressed in human 1321N1 cells assessed as benzoyl-ATP-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50412144(CHEMBL494625)
Affinity DataIC50:  145nMAssay Description:Antagonist activity at rat recombinant P2X7 receptor expressed in human 1321N1 cells assessed as benzoyl-ATP-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50412166(CHEMBL496088)
Affinity DataIC50:  148nMAssay Description:Antagonist activity at rat recombinant P2X7 receptor expressed in human 1321N1 cells assessed as benzoyl-ATP-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50412167(CHEMBL454045)
Affinity DataIC50:  148nMAssay Description:Antagonist activity at human recombinant P2X7 receptor expressed in human 1321N1 cells assessed as benzoyl-ATP-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50412150(CHEMBL525541)
Affinity DataIC50:  151nMAssay Description:Antagonist activity at rat recombinant P2X7 receptor expressed in human 1321N1 cells assessed as benzoyl-ATP-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50412165(CHEMBL509756)
Affinity DataIC50:  151nMAssay Description:Antagonist activity at rat recombinant P2X7 receptor expressed in human 1321N1 cells assessed as benzoyl-ATP-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50412163(CHEMBL496087)
Affinity DataIC50:  151nMAssay Description:Antagonist activity at rat recombinant P2X7 receptor expressed in human 1321N1 cells assessed as benzoyl-ATP-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50412169(CHEMBL494989)
Affinity DataIC50:  155nMAssay Description:Antagonist activity at rat recombinant P2X7 receptor expressed in human 1321N1 cells assessed as benzoyl-ATP-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50412147(CHEMBL451692)
Affinity DataIC50:  158nMAssay Description:Antagonist activity at human recombinant P2X7 receptor expressed in differentiated human THP1 cells assessed as inhibition of benzoyl-ATP-induced IL1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50412139(CHEMBL523385)
Affinity DataIC50:  174nMAssay Description:Antagonist activity at rat recombinant P2X7 receptor expressed in human 1321N1 cells assessed as benzoyl-ATP-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50412148(CHEMBL523540)
Affinity DataIC50:  174nMAssay Description:Antagonist activity at rat recombinant P2X7 receptor expressed in human 1321N1 cells assessed as benzoyl-ATP-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50412170(CHEMBL445485)
Affinity DataIC50:  174nMAssay Description:Antagonist activity at human recombinant P2X7 receptor expressed in human 1321N1 cells assessed as benzoyl-ATP-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50412141(CHEMBL521670)
Affinity DataIC50:  191nMAssay Description:Antagonist activity at human recombinant P2X7 receptor expressed in human 1321N1 cells assessed as benzoyl-ATP-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50412136(CHEMBL495159)
Affinity DataIC50:  195nMAssay Description:Antagonist activity at rat recombinant P2X7 receptor expressed in human 1321N1 cells assessed as benzoyl-ATP-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50412169(CHEMBL494989)
Affinity DataIC50:  200nMAssay Description:Antagonist activity at human recombinant P2X7 receptor expressed in human 1321N1 cells assessed as benzoyl-ATP-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50412158(CHEMBL505953)
Affinity DataIC50:  204nMAssay Description:Antagonist activity at rat recombinant P2X7 receptor expressed in human 1321N1 cells assessed as benzoyl-ATP-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50412152(CHEMBL510265)
Affinity DataIC50:  219nMAssay Description:Antagonist activity at human recombinant P2X7 receptor expressed in human 1321N1 cells assessed as benzoyl-ATP-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

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