Compile Data Set for Download or QSAR
maximum 50k data
Found 35 Enz. Inhib. hit(s) with all data for entry = 50038487
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50377038(CHEMBL258205)
Affinity DataIC50:  0.200nMAssay Description:Binding affinity at human CCR2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50377039(CHEMBL257191)
Affinity DataIC50:  0.600nMAssay Description:Binding affinity at human CCR2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50377034(CHEMBL256301)
Affinity DataIC50:  0.600nMAssay Description:Binding affinity at human CCR2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50377026(CHEMBL254772)
Affinity DataIC50:  1nMAssay Description:Binding affinity at human CCR2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50377027(CHEMBL404904)
Affinity DataIC50:  1nMAssay Description:Binding affinity at human CCR2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50377025(CHEMBL403889)
Affinity DataIC50:  1nMAssay Description:Binding affinity at human CCR2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50377040(CHEMBL402442)
Affinity DataIC50:  2nMAssay Description:Binding affinity at human CCR2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50377028(CHEMBL255302)
Affinity DataIC50:  2nMAssay Description:Binding affinity at human CCR2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50239941((S)-1-(4-(1-(4-(1H-indol-3-yl)piperidin-1-yl)-2-hy...)
Affinity DataIC50:  2.40nMAssay Description:Binding affinity at human CCR2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50239941((S)-1-(4-(1-(4-(1H-indol-3-yl)piperidin-1-yl)-2-hy...)
Affinity DataIC50:  3.5nMAssay Description:Antagonist activity at CCR2 receptor expressed in THP1 cells assessed as MCP-1-induced calcium flux by chemotoxis assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50239941((S)-1-(4-(1-(4-(1H-indol-3-yl)piperidin-1-yl)-2-hy...)
Affinity DataIC50:  4nMAssay Description:Binding affinity at human CCR2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50224511((E)-2-(4-(1H-indol-3-yl)piperidin-1-yl)-2-(1-(3-(3...)
Affinity DataIC50:  5nMAssay Description:Binding affinity at human CCR2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50377029(CHEMBL255499)
Affinity DataIC50:  6nMAssay Description:Binding affinity at human CCR2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50377041(CHEMBL257173)
Affinity DataIC50:  6nMAssay Description:Binding affinity at human CCR2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50377035(CHEMBL257628)
Affinity DataIC50:  7nMAssay Description:Binding affinity at human CCR2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50377023(CHEMBL438353)
Affinity DataIC50:  9nMAssay Description:Binding affinity at human CCR2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50377042(CHEMBL257385)
Affinity DataIC50:  9nMAssay Description:Binding affinity at human CCR2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50377030(CHEMBL255500)
Affinity DataIC50:  10nMAssay Description:Binding affinity at human CCR2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50377022(CHEMBL403581)
Affinity DataIC50:  10nMAssay Description:Binding affinity at human CCR2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50377020(CHEMBL257768)
Affinity DataIC50:  10nMAssay Description:Binding affinity at human CCR2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50377043(CHEMBL403250)
Affinity DataIC50:  10nMAssay Description:Binding affinity at human CCR2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50377031(CHEMBL402749)
Affinity DataIC50:  20nMAssay Description:Binding affinity at human CCR2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50377044(CHEMBL257143)
Affinity DataIC50:  20nMAssay Description:Binding affinity at human CCR2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50377036(CHEMBL255680)
Affinity DataIC50:  20nMAssay Description:Binding affinity at human CCR2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50377037(CHEMBL258204)
Affinity DataIC50:  30nMAssay Description:Binding affinity at human CCR2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50377032(CHEMBL402955)
Affinity DataIC50:  40nMAssay Description:Binding affinity at human CCR2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50377024(CHEMBL255266)
Affinity DataIC50:  40nMAssay Description:Binding affinity at human CCR2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50377033(CHEMBL401744)
Affinity DataIC50:  50nMAssay Description:Binding affinity at human CCR2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50377021(CHEMBL402801)
Affinity DataIC50:  50nMAssay Description:Binding affinity at human CCR2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50377045(CHEMBL257351)
Affinity DataIC50:  80nMAssay Description:Binding affinity at human CCR2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50224520((E)-1-(4-((4-(1H-indol-3-yl)piperidin-1-yl)methyl)...)
Affinity DataIC50:  470nMAssay Description:Binding affinity at human CCR2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50224504((E)-2-(4-(1H-indol-3-yl)piperidin-1-yl)-2-(1-(3-(3...)
Affinity DataIC50:  1.80E+3nMAssay Description:Binding affinity at human CCR2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50377046(CHEMBL258252)
Affinity DataIC50:  2.40E+3nMAssay Description:Binding affinity at human CCR2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50224509((E)-methyl 2-(4-(1H-indol-3-yl)piperidin-1-yl)-2-(...)
Affinity DataIC50:  3.30E+3nMAssay Description:Binding affinity at human CCR2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50377019(CHEMBL255687)
Affinity DataIC50:  4.80E+3nMAssay Description:Binding affinity at human CCR2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed