Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50026285
TargetGamma-aminobutyric acid receptor subunit rho-1(Human)
University of Sydney

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50087271BDBM50087271(4-Amino-but-2-enoic acid | (E)-4-Amino-but-2-enoic...)
Affinity DataEC50:  400nMAssay Description:Agonist activity at human GABAc Rho1 receptor expressed in Xenopus oocytes assessed as whole cell current production by two electrode voltage clamp m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Human)
University of Sydney

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 24183BDBM24183(4-amino-n-[2,3-3H]butyric acid | cid_119 | Gamma-A...)
Affinity DataEC50:  800nMAssay Description:Agonist activity at human GABAc Rho1 receptor expressed in Xenopus oocytes assessed as whole cell current production by two electrode voltage clamp m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGamma-aminobutyric acid receptor subunit rho-1(Human)
University of Sydney

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 23183BDBM23183(CHEMBL273481 | Muscimol | 5-(aminomethyl)-1,2-oxaz...)
Affinity DataEC50:  1.40E+3nMAssay Description:Agonist activity at human GABAc Rho1 receptor expressed in Xenopus oocytes assessed as whole cell current production by two electrode voltage clamp m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGamma-aminobutyric acid type B receptor subunit 1(Human)
University of Sydney

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 24183BDBM24183(4-amino-n-[2,3-3H]butyric acid | cid_119 | Gamma-A...)
Affinity DataEC50:  1.70E+3nMAssay Description:Agonist activity at human GABAb 1A/2 receptor expressed in Xenopus oocytes assessed as whole cell current production by two electrode voltage clamp m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGamma-aminobutyric acid receptor subunit rho-1(Human)
University of Sydney

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50032973BDBM50032973(3-aminoprop-1-enyl(methyl)phosphinic acid | CGP445...)
Affinity DataIC50: 5.50E+3nMAssay Description:Antagonist activity at human GABAc Rho1 receptor expressed in Xenopus oocytes assessed as whole cell current production by two electrode voltage clam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Human)
University of Sydney

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50243926BDBM50243926((1R,2R)-2-(aminomethyl)cyclopropanecarboxylic acid...)
Affinity DataEC50:  9.00E+3nMAssay Description:Agonist activity at human GABAc Rho1 receptor expressed in Xenopus oocytes assessed as whole cell current production by two electrode voltage clamp m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Human)
University of Sydney

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50240386BDBM50240386(5-amino-4-oxopentanoic acid | 5-aminolevulinic aci...)
Affinity DataIC50: 1.29E+4nMAssay Description:Antagonist activity at human GABAc Rho1 receptor expressed in Xenopus oocytes assessed as whole cell current production by two electrode voltage clam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Human)
University of Sydney

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50243877BDBM50243877((1R,2S)-2-(aminomethyl)cyclopropanecarboxylic acid...)
Affinity DataEC50:  4.00E+4nMAssay Description:Agonist activity at human GABAc Rho1 receptor expressed in Xenopus oocytes assessed as whole cell current production by two electrode voltage clamp m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGamma-aminobutyric acid type B receptor subunit 1(Human)
University of Sydney

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50243872BDBM50243872((+/-)-4-Amino-1-cyclopent-1-enyl(methyl)phosphinic...)
Affinity DataEC50:  5.10E+4nMAssay Description:Agonist activity at human GABAb 1A/2 receptor expressed in Xenopus oocytes assessed as whole cell current production by two electrode voltage clamp m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGamma-aminobutyric acid type B receptor subunit 1(Human)
University of Sydney

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50243874BDBM50243874((+)-(S)-4-Amino-1-cyclopent-1-enyl(methyl)phosphin...)
Affinity DataEC50:  5.22E+4nMAssay Description:Agonist activity at human GABAb 1A/2 receptor expressed in Xenopus oocytes assessed as whole cell current production by two electrode voltage clamp m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Human)
University of Sydney

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50243927BDBM50243927((1S,2S)-2-(aminomethyl)cyclopropanecarboxylic acid...)
Affinity DataEC50:  5.90E+4nMAssay Description:Agonist activity at human GABAc Rho1 receptor expressed in Xenopus oocytes assessed as whole cell current production by two electrode voltage clamp m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Human)
University of Sydney

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50032982BDBM50032982(CGP36742 | 3-aminopropyl(butyl)phosphinic acid | C...)
Affinity DataIC50: 6.20E+4nMAssay Description:Antagonist activity at human GABAc Rho1 receptor expressed in Xenopus oocytes assessed as whole cell current production by two electrode voltage clam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGamma-aminobutyric acid type B receptor subunit 1(Human)
University of Sydney

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50243873BDBM50243873((-)-(R)-4-Amino-1-cyclopent-1-enyl(methyl)phosphin...)
Affinity DataEC50:  7.19E+4nMAssay Description:Agonist activity at human GABAb 1A/2 receptor expressed in Xenopus oocytes assessed as whole cell current production by two electrode voltage clamp m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Human)
University of Sydney

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50087277BDBM50087277(4-aminobut-2-enoic acid | (Z)-4-aminobut-2-enoic a...)
Affinity DataEC50:  7.40E+4nMAssay Description:Agonist activity at human GABAc Rho1 receptor expressed in Xenopus oocytes assessed as whole cell current production by two electrode voltage clamp m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Human)
University of Sydney

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50243875BDBM50243875(cis-3-Amino-cyclobutyl(methyl)phosphinic acid | CH...)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at human GABAc Rho1 receptor expressed in Xenopus oocytes assessed as whole cell current production by two electrode voltage clam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Human)
University of Sydney

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50243876BDBM50243876(trans-3-Amino-cyclobutyl(methyl)phosphinic acid | ...)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at human GABAc Rho1 receptor expressed in Xenopus oocytes assessed as whole cell current production by two electrode voltage clam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGamma-aminobutyric acid type B receptor subunit 1(Human)
University of Sydney

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211642BDBM50211642(methyl(1,2,3,6-tetrahydropyridin-4-yl)phosphinic a...)
Affinity DataEC50:  5.00E+5nMAssay Description:Agonist activity at human GABAb 1A/2 receptor expressed in Xenopus oocytes assessed as whole cell current production by two electrode voltage clamp m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit rho-1(Human)
University of Sydney

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50241194BDBM50241194((1S,2R)-2-aminomethyl-cyclopropanecarboxylic acid ...)
Affinity DataIC50: 8.00E+5nMAssay Description:Antagonist activity at human GABAc Rho1 receptor expressed in Xenopus oocytes assessed as whole cell current production by two electrode voltage clam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed