Compile Data Set for Download or QSAR
maximum 50k data
Found 28 Enz. Inhib. hit(s) with all data for entry = 50026367
TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50243440((-)-7,9-difluoro-5-(6-methyl-7-oxa-bicyclo[4.1.0]h...)
Affinity DataKi:  1.20nMAssay Description:Binding affinity at human progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50067678((6alpha)-17-(Acetyloxy)-6-methylpreg-4-ene-3,20-di...)
Affinity DataKi:  1.40nMAssay Description:Binding affinity at human progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM8903((1S,2R,10S,11S,14S,15S)-14-acetyl-2,15-dimethyltet...)
Affinity DataKi:  3.40nMAssay Description:Binding affinity at human progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50243394((+)-(S)-7,9-difluoro-2,2,4-trimethyl-5-((S)-3-meth...)
Affinity DataKi:  4.40nMAssay Description:Binding affinity at human progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50243394((+)-(S)-7,9-difluoro-2,2,4-trimethyl-5-((S)-3-meth...)
Affinity DataKi:  4.40nMAssay Description:Binding affinity at human progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50243346(CHEMBL510305 | rac, syn-5-(cyclohex-2-en-1-yl)-7,9...)
Affinity DataKi:  4.80nMAssay Description:Binding affinity at human progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50243395(CHEMBL510373 | rac, anti-7,9-difluoro-5-(3-methylc...)
Affinity DataKi:  14nMAssay Description:Binding affinity at human progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50243394((+)-(S)-7,9-difluoro-2,2,4-trimethyl-5-((S)-3-meth...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity at human progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50243394((+)-(S)-7,9-difluoro-2,2,4-trimethyl-5-((S)-3-meth...)
Affinity DataIC50:  34nMAssay Description:Antagonist activity at human glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50243394((+)-(S)-7,9-difluoro-2,2,4-trimethyl-5-((S)-3-meth...)
Affinity DataIC50:  1.35E+3nMAssay Description:Antagonist activity at human mineralocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM8903((1S,2R,10S,11S,14S,15S)-14-acetyl-2,15-dimethyltet...)
Affinity DataEC50:  2.20nMAssay Description:Agonist activity at human progesterone receptor in human T47D cells assessed as alkaline phosphatase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50243440((-)-7,9-difluoro-5-(6-methyl-7-oxa-bicyclo[4.1.0]h...)
Affinity DataEC50:  2.80nMAssay Description:Agonist activity at human progesterone receptor in human T47D cells assessed as alkaline phosphatase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50243439(CHEMBL507532 | rac, syn-7,9-difluoro-5-(3-methylcy...)
Affinity DataEC50:  96nMAssay Description:Agonist activity at human progesterone receptor in human T47D cells assessed as alkaline phosphatase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50243394((+)-(S)-7,9-difluoro-2,2,4-trimethyl-5-((S)-3-meth...)
Affinity DataEC50:  4.30nMAssay Description:Agonist activity at human progesterone receptor in human T47D cells assessed as alkaline phosphatase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50243395(CHEMBL510373 | rac, anti-7,9-difluoro-5-(3-methylc...)
Affinity DataEC50:  33nMAssay Description:Agonist activity at human progesterone receptor in human T47D cells assessed as alkaline phosphatase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50243394((+)-(S)-7,9-difluoro-2,2,4-trimethyl-5-((S)-3-meth...)
Affinity DataEC50:  4.30nMAssay Description:Agonist activity at human progesterone receptor in human T47D cells assessed as alkaline phosphatase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50243394((+)-(S)-7,9-difluoro-2,2,4-trimethyl-5-((S)-3-meth...)
Affinity DataEC50:  1.80E+3nMAssay Description:Agonist activity at human androgen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50067678((6alpha)-17-(Acetyloxy)-6-methylpreg-4-ene-3,20-di...)
Affinity DataEC50:  0.400nMAssay Description:Agonist activity at human progesterone receptor in human T47D cells assessed as alkaline phosphatase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50243394((+)-(S)-7,9-difluoro-2,2,4-trimethyl-5-((S)-3-meth...)
Affinity DataEC50:  0.5nMAssay Description:Agonist activity at human progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50243395(CHEMBL510373 | rac, anti-7,9-difluoro-5-(3-methylc...)
Affinity DataEC50:  5.40nMAssay Description:Agonist activity at human progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50243394((+)-(S)-7,9-difluoro-2,2,4-trimethyl-5-((S)-3-meth...)
Affinity DataEC50:  50.8nMAssay Description:Agonist activity at human progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50243394((+)-(S)-7,9-difluoro-2,2,4-trimethyl-5-((S)-3-meth...)
Affinity DataEC50:  50.8nMAssay Description:Agonist activity at human progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50243439(CHEMBL507532 | rac, syn-7,9-difluoro-5-(3-methylcy...)
Affinity DataEC50:  10.7nMAssay Description:Agonist activity at human progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50243440((-)-7,9-difluoro-5-(6-methyl-7-oxa-bicyclo[4.1.0]h...)
Affinity DataEC50:  0.400nMAssay Description:Agonist activity at human progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM8903((1S,2R,10S,11S,14S,15S)-14-acetyl-2,15-dimethyltet...)
Affinity DataEC50:  0.5nMAssay Description:Agonist activity at human progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50067678((6alpha)-17-(Acetyloxy)-6-methylpreg-4-ene-3,20-di...)
Affinity DataEC50:  0.5nMAssay Description:Agonist activity at human progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50243346(CHEMBL510305 | rac, syn-5-(cyclohex-2-en-1-yl)-7,9...)
Affinity DataEC50:  3.40nMAssay Description:Agonist activity at human progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50243346(CHEMBL510305 | rac, syn-5-(cyclohex-2-en-1-yl)-7,9...)
Affinity DataEC50:  27nMAssay Description:Agonist activity at human progesterone receptor in human T47D cells assessed as alkaline phosphatase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed