Compile Data Set for Download or QSAR
maximum 50k data
Found 13 Enz. Inhib. hit(s) with all data for entry = 50026518
TargetHexokinase-4(Homo sapiens (Human))
(Osi) Prosidion

Curated by ChEMBL
LigandPNGBDBM50251802((E)-2-phenyl-N-(pyrazin-2-yl)-3-(thiophen-2-yl)acr...)
Affinity DataEC50:  2.60E+4nMAssay Description:Activation of GST fused human liver glucokinase assessed as generation of NADPH by G6PDH coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
(Osi) Prosidion

Curated by ChEMBL
LigandPNGBDBM50251450((R)-2-(4-(cyclopentylsulfonyl)phenyl)-N-(5-fluorot...)
Affinity DataEC50:  70nMAssay Description:Activation of GST fused human liver glucokinase assessed as generation of NADPH by G6PDH coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
(Osi) Prosidion

Curated by ChEMBL
LigandPNGBDBM50251421((R)-2-(4-(cyclobutylsulfonyl)phenyl)-N-(5-fluoroth...)
Affinity DataEC50:  140nMAssay Description:Activation of GST fused human liver glucokinase assessed as generation of NADPH by G6PDH coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
(Osi) Prosidion

Curated by ChEMBL
LigandPNGBDBM50251392((R)-N-(5-fluorothiazol-2-yl)-2-(4-(methylsulfonyl)...)
Affinity DataEC50:  1.43E+3nMAssay Description:Activation of GST fused human liver glucokinase assessed as generation of NADPH by G6PDH coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
(Osi) Prosidion

Curated by ChEMBL
LigandPNGBDBM50251391((2R)-2-(4-Cyclopropanesulfonylphenyl)-N-(5-fluorot...)
Affinity DataEC50:  130nMAssay Description:Activation of GST fused human liver glucokinase assessed as generation of NADPH by G6PDH coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
(Osi) Prosidion

Curated by ChEMBL
LigandPNGBDBM50251390((R)-2-(4-(cyclopropylsulfonyl)phenyl)-N-(5-methylt...)
Affinity DataEC50:  580nMAssay Description:Activation of GST fused human liver glucokinase assessed as generation of NADPH by G6PDH coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
(Osi) Prosidion

Curated by ChEMBL
LigandPNGBDBM50251829(2-phenyl-N-(thiazol-2-yl)-3-(thiophen-2-yl)acrylam...)
Affinity DataEC50:  1.08E+4nMAssay Description:Activation of GST fused human liver glucokinase assessed as generation of NADPH by G6PDH coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
(Osi) Prosidion

Curated by ChEMBL
LigandPNGBDBM50251388((S)-2-(4-(methylsulfonyl)phenyl)-3-(tetrahydro-2H-...)
Affinity DataEC50: >1.00E+4nMAssay Description:Activation of GST fused human liver glucokinase assessed as generation of NADPH by G6PDH coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
(Osi) Prosidion

Curated by ChEMBL
LigandPNGBDBM50251833((R)-2-(4-(methylsulfonyl)phenyl)-3-(tetrahydro-2H-...)
Affinity DataEC50:  3.47E+3nMAssay Description:Activation of GST fused human liver glucokinase assessed as generation of NADPH by G6PDH coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
(Osi) Prosidion

Curated by ChEMBL
LigandPNGBDBM50251832(2-(4-(methylsulfonyl)phenyl)-3-(tetrahydro-2H-pyra...)
Affinity DataEC50:  8.93E+3nMAssay Description:Activation of GST fused human liver glucokinase assessed as generation of NADPH by G6PDH coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
(Osi) Prosidion

Curated by ChEMBL
LigandPNGBDBM50251831(2-(4-(methylsulfonyl)phenyl)-3-(tetrahydro-2H-pyra...)
Affinity DataEC50:  2.30E+3nMAssay Description:Activation of GST fused human liver glucokinase assessed as generation of NADPH by G6PDH coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
(Osi) Prosidion

Curated by ChEMBL
LigandPNGBDBM50251830((Z)-2-(4-(methylsulfonyl)phenyl)-N-(thiazol-2-yl)-...)
Affinity DataEC50:  560nMAssay Description:Activation of GST fused human liver glucokinase assessed as generation of NADPH by G6PDH coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
(Osi) Prosidion

Curated by ChEMBL
LigandPNGBDBM50251389((R)-2-(4-(cyclopropylsulfonyl)phenyl)-3-(tetrahydr...)
Affinity DataEC50:  570nMAssay Description:Activation of GST fused human liver glucokinase assessed as generation of NADPH by G6PDH coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed