Compile Data Set for Download or QSAR
maximum 50k data
Found 28 Enz. Inhib. hit(s) with all data for entry = 50026552
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Universita Di Siena

Curated by ChEMBL
LigandPNGBDBM50262934(CHEMBL477362 | [3-(2-Ethoxyethyl)-2-methyl-5-(4-me...)
Affinity DataIC50:  15nMAssay Description:Inhibition of mouse COX2 in LPS-stimulated mouse J774 cells assessed as PGE2 production by radioimmunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Universita Di Siena

Curated by ChEMBL
LigandPNGBDBM50262990(CHEMBL517675 | [2-Methyl-5-(4-methylsulphonyl)phen...)
Affinity DataIC50:  18nMAssay Description:Inhibition of mouse COX2 in LPS-stimulated mouse J774 cells assessed as PGE2 production by radioimmunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Universita Di Siena

Curated by ChEMBL
LigandPNGBDBM50262933(CHEMBL451358 | [1-(4-Fluoro)phenyl-2-methyl-5-(4-m...)
Affinity DataIC50:  18nMAssay Description:Inhibition of mouse COX2 in LPS-stimulated mouse J774 cells assessed as PGE2 production by radioimmunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Universita Di Siena

Curated by ChEMBL
LigandPNGBDBM50262992(CHEMBL479054 | [1-(4-Fluoro)phenyl-2-methyl-5-(4-m...)
Affinity DataIC50:  30nMAssay Description:Inhibition of mouse COX2 in LPS-stimulated mouse J774 cells assessed as PGE2 production by radioimmunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Universita Di Siena

Curated by ChEMBL
LigandPNGBDBM50166278(CHEMBL191941 | [5-(4-Methanesulfonyl-phenyl)-2-met...)
Affinity DataIC50:  40nMAssay Description:Inhibition of mouse COX2 in LPS-stimulated mouse J774 cells assessed as PGE2 production by radioimmunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Universita Di Siena

Curated by ChEMBL
LigandPNGBDBM50262989(CHEMBL476536 | [3-(2-Ethoxyethyl)-1-(4-Fluoro)phen...)
Affinity DataIC50:  47nMAssay Description:Inhibition of mouse COX2 in LPS-stimulated mouse J774 cells assessed as PGE2 production by radioimmunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Universita Di Siena

Curated by ChEMBL
LigandPNGBDBM50262931(CHEMBL516289 | [2-Methyl-5-(4-methylsulphonyl)phen...)
Affinity DataIC50:  48nMAssay Description:Inhibition of mouse COX2 in LPS-stimulated mouse J774 cells assessed as PGE2 production by radioimmunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Universita Di Siena

Curated by ChEMBL
LigandPNGBDBM50262932(CHEMBL478415 | [2-Methyl-5-(4-methylsulphonyl)phen...)
Affinity DataIC50:  49nMAssay Description:Inhibition of mouse COX2 in LPS-stimulated mouse J774 cells assessed as PGE2 production by radioimmunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Universita Di Siena

Curated by ChEMBL
LigandPNGBDBM50166281(CHEMBL192789 | [5-(4-Methanesulfonyl-phenyl)-2-met...)
Affinity DataIC50:  60nMAssay Description:Inhibition of mouse COX2 in LPS-stimulated mouse J774 cells assessed as PGE2 production by radioimmunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Universita Di Siena

Curated by ChEMBL
LigandPNGBDBM50262935(CHEMBL515478 | [3-(2-Ethoxyethyl)-2-methyl-5-(4-me...)
Affinity DataIC50:  85nMAssay Description:Inhibition of mouse COX2 in LPS-stimulated mouse J774 cells assessed as PGE2 production by radioimmunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Universita Di Siena

Curated by ChEMBL
LigandPNGBDBM50262991(CHEMBL479053 | [2-Methyl-5-(4-methylsulphonyl)phen...)
Affinity DataIC50:  110nMAssay Description:Inhibition of mouse COX2 in LPS-stimulated mouse J774 cells assessed as PGE2 production by radioimmunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Universita Di Siena

Curated by ChEMBL
LigandPNGBDBM50166276(CHEMBL363398 | [5-(4-Methanesulfonyl-phenyl)-2-met...)
Affinity DataIC50:  480nMAssay Description:Inhibition of mouse COX2 in LPS-stimulated mouse J774 cells assessed as PGE2 production by radioimmunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Universita Di Siena

Curated by ChEMBL
LigandPNGBDBM13063(4-(5-methyl-3-phenyl-1,2-oxazol-4-yl)benzene-1-sul...)
Affinity DataIC50:  660nMAssay Description:Inhibition of COX2 in human whole blood assessed as effect on thrombin-induced TXB2 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Universita Di Siena

Curated by ChEMBL
LigandPNGBDBM50262990(CHEMBL517675 | [2-Methyl-5-(4-methylsulphonyl)phen...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of COX2 in human whole blood assessed as effect on thrombin-induced TXB2 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Universita Di Siena

Curated by ChEMBL
LigandPNGBDBM13063(4-(5-methyl-3-phenyl-1,2-oxazol-4-yl)benzene-1-sul...)
Affinity DataIC50:  3.43E+4nMAssay Description:Inhibition of COX1 in LPS-induced human whole blood assessed as PGE2 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Universita Di Siena

Curated by ChEMBL
LigandPNGBDBM50262990(CHEMBL517675 | [2-Methyl-5-(4-methylsulphonyl)phen...)
Affinity DataIC50:  8.60E+4nMAssay Description:Inhibition of COX1 in LPS-induced human whole blood assessed as PGE2 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Mus musculus)
Universita Di Siena

Curated by ChEMBL
LigandPNGBDBM50262932(CHEMBL478415 | [2-Methyl-5-(4-methylsulphonyl)phen...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of mouse COX1 in mouse J774 cells assessed as PGE2 production by radioimmunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Mus musculus)
Universita Di Siena

Curated by ChEMBL
LigandPNGBDBM50262931(CHEMBL516289 | [2-Methyl-5-(4-methylsulphonyl)phen...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of mouse COX1 in mouse J774 cells assessed as PGE2 production by radioimmunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Mus musculus)
Universita Di Siena

Curated by ChEMBL
LigandPNGBDBM50166281(CHEMBL192789 | [5-(4-Methanesulfonyl-phenyl)-2-met...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of mouse COX1 in mouse J774 cells assessed as PGE2 production by radioimmunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Mus musculus)
Universita Di Siena

Curated by ChEMBL
LigandPNGBDBM50166276(CHEMBL363398 | [5-(4-Methanesulfonyl-phenyl)-2-met...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of mouse COX1 in mouse J774 cells assessed as PGE2 production by radioimmunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Mus musculus)
Universita Di Siena

Curated by ChEMBL
LigandPNGBDBM50262934(CHEMBL477362 | [3-(2-Ethoxyethyl)-2-methyl-5-(4-me...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of mouse COX1 in mouse J774 cells assessed as PGE2 production by radioimmunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Mus musculus)
Universita Di Siena

Curated by ChEMBL
LigandPNGBDBM50262933(CHEMBL451358 | [1-(4-Fluoro)phenyl-2-methyl-5-(4-m...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of mouse COX1 in mouse J774 cells assessed as PGE2 production by radioimmunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Mus musculus)
Universita Di Siena

Curated by ChEMBL
LigandPNGBDBM50262989(CHEMBL476536 | [3-(2-Ethoxyethyl)-1-(4-Fluoro)phen...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of mouse COX1 in mouse J774 cells assessed as PGE2 production by radioimmunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Mus musculus)
Universita Di Siena

Curated by ChEMBL
LigandPNGBDBM50262990(CHEMBL517675 | [2-Methyl-5-(4-methylsulphonyl)phen...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of mouse COX1 in mouse J774 cells assessed as PGE2 production by radioimmunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Mus musculus)
Universita Di Siena

Curated by ChEMBL
LigandPNGBDBM50262991(CHEMBL479053 | [2-Methyl-5-(4-methylsulphonyl)phen...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of mouse COX1 in mouse J774 cells assessed as PGE2 production by radioimmunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Mus musculus)
Universita Di Siena

Curated by ChEMBL
LigandPNGBDBM50262992(CHEMBL479054 | [1-(4-Fluoro)phenyl-2-methyl-5-(4-m...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of mouse COX1 in mouse J774 cells assessed as PGE2 production by radioimmunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Mus musculus)
Universita Di Siena

Curated by ChEMBL
LigandPNGBDBM50166278(CHEMBL191941 | [5-(4-Methanesulfonyl-phenyl)-2-met...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of mouse COX1 in mouse J774 cells assessed as PGE2 production by radioimmunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Mus musculus)
Universita Di Siena

Curated by ChEMBL
LigandPNGBDBM50262935(CHEMBL515478 | [3-(2-Ethoxyethyl)-2-methyl-5-(4-me...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of mouse COX1 in mouse J774 cells assessed as PGE2 production by radioimmunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed