Compile Data Set for Download or QSAR
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Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 2725
TargetCalpain-1 catalytic subunit(Pig)
University of Tennessee Health Science Center

LigandPNGBDBM23865(3-[(2S)-2-[1-(9H-fluoren-9-yl)acetamido]-4-methylp...)
Affinity DataKi:  8nM ΔG°:  -45.7kJ/molepH: 7.4 T: 22°CAssay Description:Assays were initiated by addition of CaCl2, and the increase in fluorescence (ex @370 nm, em @440 nm) was monitored. MDL28170 and buffer with 2% DMSO...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCalpain-1 catalytic subunit(Pig)
University of Tennessee Health Science Center

LigandPNGBDBM23866(MDL28170 | Z-Val-Phe-CHO | benzyl N-[(1S)-2-methyl...)
Affinity DataKi:  10nM ΔG°:  -45.2kJ/molepH: 7.4 T: 22°CAssay Description:Assays were initiated by addition of CaCl2, and the increase in fluorescence (ex @370 nm, em @440 nm) was monitored. MDL28170 and buffer with 2% DMSO...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCalpain-1 catalytic subunit(Pig)
University of Tennessee Health Science Center

LigandPNGBDBM23859(3-[(2S)-2-[1-(adamantan-1-yl)acetamido]-4-methylpe...)
Affinity DataKi:  41nM ΔG°:  -41.7kJ/molepH: 7.4 T: 22°CAssay Description:Assays were initiated by addition of CaCl2, and the increase in fluorescence (ex @370 nm, em @440 nm) was monitored. MDL28170 and buffer with 2% DMSO...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCalpain-1 catalytic subunit(Pig)
University of Tennessee Health Science Center

LigandPNGBDBM23857(3-[(2S)-2-(3-cyclohexylpropanamido)-4-methylpentan...)
Affinity DataKi:  50nM ΔG°:  -41.3kJ/molepH: 7.4 T: 22°CAssay Description:Assays were initiated by addition of CaCl2, and the increase in fluorescence (ex @370 nm, em @440 nm) was monitored. MDL28170 and buffer with 2% DMSO...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCalpain-1 catalytic subunit(Pig)
University of Tennessee Health Science Center

LigandPNGBDBM23863(3-[(2S)-2-(3,3-diphenylpropanamido)-4-methylpentan...)
Affinity DataKi:  63nM ΔG°:  -40.7kJ/molepH: 7.4 T: 22°CAssay Description:Assays were initiated by addition of CaCl2, and the increase in fluorescence (ex @370 nm, em @440 nm) was monitored. MDL28170 and buffer with 2% DMSO...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCalpain-1 catalytic subunit(Pig)
University of Tennessee Health Science Center

LigandPNGBDBM23861(3-[(2S)-2-(1,1-diphenylacetamido)-4-methylpentanam...)
Affinity DataKi:  108nM ΔG°:  -39.4kJ/molepH: 7.4 T: 22°CAssay Description:Assays were initiated by addition of CaCl2, and the increase in fluorescence (ex @370 nm, em @440 nm) was monitored. MDL28170 and buffer with 2% DMSO...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCalpain-1 catalytic subunit(Pig)
University of Tennessee Health Science Center

LigandPNGBDBM23858(Peptidyl alpha-Ketoester, 1b | methyl 3-[(2S)-2-[1...)
Affinity DataKi:  450nM ΔG°:  -35.9kJ/molepH: 7.4 T: 22°CAssay Description:Assays were initiated by addition of CaCl2, and the increase in fluorescence (ex @370 nm, em @440 nm) was monitored. MDL28170 and buffer with 2% DMSO...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCalpain-1 catalytic subunit(Pig)
University of Tennessee Health Science Center

LigandPNGBDBM23860(Peptidyl alpha-Ketoester, 1c | methyl 3-[(2S)-2-(1...)
Affinity DataKi:  944nM ΔG°:  -34.0kJ/molepH: 7.4 T: 22°CAssay Description:Assays were initiated by addition of CaCl2, and the increase in fluorescence (ex @370 nm, em @440 nm) was monitored. MDL28170 and buffer with 2% DMSO...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCalpain-1 catalytic subunit(Pig)
University of Tennessee Health Science Center

LigandPNGBDBM23855(Peptidyl alpha-Ketoester, 1a | methyl 3-[(2S)-2-(3...)
Affinity DataKi:  1.05E+3nM ΔG°:  -33.8kJ/molepH: 7.4 T: 22°CAssay Description:Assays were initiated by addition of CaCl2, and the increase in fluorescence (ex @370 nm, em @440 nm) was monitored. MDL28170 and buffer with 2% DMSO...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCalpain-1 catalytic subunit(Pig)
University of Tennessee Health Science Center

LigandPNGBDBM23864(Peptidyl alpha-Ketoester, 1e | methyl 3-[(2S)-2-[1...)
Affinity DataKi:  1.20E+3nM ΔG°:  -33.5kJ/molepH: 7.4 T: 22°CAssay Description:Assays were initiated by addition of CaCl2, and the increase in fluorescence (ex @370 nm, em @440 nm) was monitored. MDL28170 and buffer with 2% DMSO...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCalpain-1 catalytic subunit(Pig)
University of Tennessee Health Science Center

LigandPNGBDBM23862(Peptidyl alpha-Ketoester, 1d | methyl 3-[(2S)-2-(3...)
Affinity DataKi:  2.15E+3nM ΔG°:  -32.0kJ/molepH: 7.4 T: 22°CAssay Description:Assays were initiated by addition of CaCl2, and the increase in fluorescence (ex @370 nm, em @440 nm) was monitored. MDL28170 and buffer with 2% DMSO...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed