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Report error Found 76 Enz. Inhib. hit(s) with all data for entry = 50026682
TargetHistone deacetylase 6(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50261816(CHEMBL511749 | tert-butyl 4-(3-((7-(hydroxyamino)-...)
Affinity DataIC50:  0.00200nMAssay Description:Inhibition of HDAC6 (unknown origin) after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 3(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50261816(CHEMBL511749 | tert-butyl 4-(3-((7-(hydroxyamino)-...)
Affinity DataIC50:  0.420nMAssay Description:Inhibition of HDAC3 (unknown origin) after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 6(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Affinity DataIC50:  1nMAssay Description:Inhibition of HDAC6 (unknown origin) after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetHistone deacetylase 8(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Affinity DataIC50:  1.38nMAssay Description:Inhibition of HDAC8 (unknown origin) after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetHistone deacetylase 3(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Affinity DataIC50:  2nMAssay Description:Inhibition of HDAC3 (unknown origin) after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 6(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50261753(5-(3-aminophenyl)-N-(7-(hydroxyamino)-7-oxoheptyl)...)
Affinity DataIC50:  2.54nMAssay Description:Inhibition of HDAC6 (unknown origin) after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 6(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50261752(CHEMBL469275 | tert-butyl 3-(3-((5-(hydroxyamino)-...)
Affinity DataIC50:  3.98nMAssay Description:Inhibition of HDAC6 (unknown origin) after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 1(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Affinity DataIC50:  4nMAssay Description:Inhibition of HDAC1 (unknown origin) after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 3(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50261753(5-(3-aminophenyl)-N-(7-(hydroxyamino)-7-oxoheptyl)...)
Affinity DataIC50:  4.04nMAssay Description:Inhibition of HDAC3 (unknown origin) after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyamine deacetylase HDAC10(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Affinity DataIC50:  5nMAssay Description:Inhibition of HDAC10 (unknown origin) after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 6(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50261818(5-(4-aminophenyl)-N-(7-(hydroxyamino)-7-oxoheptyl)...)
Affinity DataIC50:  5.86nMAssay Description:Inhibition of HDAC6 (unknown origin) after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 6(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50261820(5-(4-acetamidophenyl)-N-(7-(hydroxyamino)-7-oxohep...)
Affinity DataIC50:  6.81nMAssay Description:Inhibition of HDAC6 (unknown origin) after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 3(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50261818(5-(4-aminophenyl)-N-(7-(hydroxyamino)-7-oxoheptyl)...)
Affinity DataIC50:  10.2nMAssay Description:Inhibition of HDAC3 (unknown origin) after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 3(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50261972(CHEMBL513160 | N-hydroxy-5-((5-phenylisoxazol-3-yl...)
Affinity DataIC50:  12.9nMAssay Description:Inhibition of HDAC3 (unknown origin) after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 6(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  14nMAssay Description:Inhibition of HDAC6 (unknown origin) after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank


TargetHistone deacetylase 2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Affinity DataIC50:  14nMAssay Description:Inhibition of HDAC2 (unknown origin) after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 3(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  17nMAssay Description:Inhibition of HDAC3 (unknown origin) after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank


TargetPolyamine deacetylase HDAC10(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50261753(5-(3-aminophenyl)-N-(7-(hydroxyamino)-7-oxoheptyl)...)
Affinity DataIC50:  17.5nMAssay Description:Inhibition of HDAC10 (unknown origin) after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 3(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50261820(5-(4-acetamidophenyl)-N-(7-(hydroxyamino)-7-oxohep...)
Affinity DataIC50:  18nMAssay Description:Inhibition of HDAC3 (unknown origin) after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 1(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50261753(5-(3-aminophenyl)-N-(7-(hydroxyamino)-7-oxoheptyl)...)
Affinity DataIC50:  20.7nMAssay Description:Inhibition of HDAC1 (unknown origin) after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyamine deacetylase HDAC10(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50261751(CHEMBL469274 | tert-butyl 3-(3-((7-(hydroxyamino)-...)
Affinity DataIC50:  28.2nMAssay Description:Inhibition of HDAC10 (unknown origin) after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 6(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50261817(CHEMBL467792 | tert-butyl 4-(3-((5-(hydroxyamino)-...)
Affinity DataIC50:  31.6nMAssay Description:Inhibition of HDAC6 (unknown origin) after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 6(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50261819(5-(4-aminophenyl)-N-(5-(hydroxyamino)-5-oxopentyl)...)
Affinity DataIC50:  35.1nMAssay Description:Inhibition of HDAC6 (unknown origin) after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyamine deacetylase HDAC10(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50261818(5-(4-aminophenyl)-N-(7-(hydroxyamino)-7-oxoheptyl)...)
Affinity DataIC50:  44.9nMAssay Description:Inhibition of HDAC10 (unknown origin) after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 6(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50261972(CHEMBL513160 | N-hydroxy-5-((5-phenylisoxazol-3-yl...)
Affinity DataIC50:  49.5nMAssay Description:Inhibition of HDAC6 (unknown origin) after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 1(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50261818(5-(4-aminophenyl)-N-(7-(hydroxyamino)-7-oxoheptyl)...)
Affinity DataIC50:  56.3nMAssay Description:Inhibition of HDAC1 (unknown origin) after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50261753(5-(3-aminophenyl)-N-(7-(hydroxyamino)-7-oxoheptyl)...)
Affinity DataIC50:  56.7nMAssay Description:Inhibition of HDAC2 (unknown origin) after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 6(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50261973(CHEMBL467998 | N-(5-(hydroxyamino)-5-oxopentyl)-5-...)
Affinity DataIC50:  61.9nMAssay Description:Inhibition of HDAC6 (unknown origin) after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 1(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50261820(5-(4-acetamidophenyl)-N-(7-(hydroxyamino)-7-oxohep...)
Affinity DataIC50:  64.5nMAssay Description:Inhibition of HDAC1 (unknown origin) after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 3(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50261819(5-(4-aminophenyl)-N-(5-(hydroxyamino)-5-oxopentyl)...)
Affinity DataIC50:  65.8nMAssay Description:Inhibition of HDAC3 (unknown origin) after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyamine deacetylase HDAC10(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  72nMAssay Description:Inhibition of HDAC10 (unknown origin) after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 6(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50261754(5-(3-aminophenyl)-N-(5-(hydroxyamino)-5-oxopentyl)...)
Affinity DataIC50:  72.2nMAssay Description:Inhibition of HDAC6 (unknown origin) after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyamine deacetylase HDAC10(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50261820(5-(4-acetamidophenyl)-N-(7-(hydroxyamino)-7-oxohep...)
Affinity DataIC50:  73nMAssay Description:Inhibition of HDAC10 (unknown origin) after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 3(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50261752(CHEMBL469275 | tert-butyl 3-(3-((5-(hydroxyamino)-...)
Affinity DataIC50:  83.6nMAssay Description:Inhibition of HDAC3 (unknown origin) after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyamine deacetylase HDAC10(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50261816(CHEMBL511749 | tert-butyl 4-(3-((7-(hydroxyamino)-...)
Affinity DataIC50:  90.7nMAssay Description:Inhibition of HDAC10 (unknown origin) after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 1(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  96nMAssay Description:Inhibition of HDAC1 (unknown origin) after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank
PDB3D3D Structure (crystal)

TargetHistone deacetylase 1(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50261751(CHEMBL469274 | tert-butyl 3-(3-((7-(hydroxyamino)-...)
Affinity DataIC50:  100nMAssay Description:Inhibition of HDAC1 (unknown origin) after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 3(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50261817(CHEMBL467792 | tert-butyl 4-(3-((5-(hydroxyamino)-...)
Affinity DataIC50:  115nMAssay Description:Inhibition of HDAC3 (unknown origin) after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 1(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50261972(CHEMBL513160 | N-hydroxy-5-((5-phenylisoxazol-3-yl...)
Affinity DataIC50:  124nMAssay Description:Inhibition of HDAC1 (unknown origin) after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50261820(5-(4-acetamidophenyl)-N-(7-(hydroxyamino)-7-oxohep...)
Affinity DataIC50:  131nMAssay Description:Inhibition of HDAC2 (unknown origin) after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50261972(CHEMBL513160 | N-hydroxy-5-((5-phenylisoxazol-3-yl...)
Affinity DataIC50:  133nMAssay Description:Inhibition of HDAC2 (unknown origin) after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 3(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50261754(5-(3-aminophenyl)-N-(5-(hydroxyamino)-5-oxopentyl)...)
Affinity DataIC50:  144nMAssay Description:Inhibition of HDAC3 (unknown origin) after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50261818(5-(4-aminophenyl)-N-(7-(hydroxyamino)-7-oxoheptyl)...)
Affinity DataIC50:  147nMAssay Description:Inhibition of HDAC2 (unknown origin) after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyamine deacetylase HDAC10(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50261972(CHEMBL513160 | N-hydroxy-5-((5-phenylisoxazol-3-yl...)
Affinity DataIC50:  155nMAssay Description:Inhibition of HDAC10 (unknown origin) after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 3(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50261973(CHEMBL467998 | N-(5-(hydroxyamino)-5-oxopentyl)-5-...)
Affinity DataIC50:  158nMAssay Description:Inhibition of HDAC3 (unknown origin) after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50261751(CHEMBL469274 | tert-butyl 3-(3-((7-(hydroxyamino)-...)
Affinity DataIC50:  238nMAssay Description:Inhibition of HDAC2 (unknown origin) after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50261816(CHEMBL511749 | tert-butyl 4-(3-((7-(hydroxyamino)-...)
Affinity DataIC50:  252nMAssay Description:Inhibition of HDAC2 (unknown origin) after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 1(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50261816(CHEMBL511749 | tert-butyl 4-(3-((7-(hydroxyamino)-...)
Affinity DataIC50:  271nMAssay Description:Inhibition of HDAC1 (unknown origin) after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  282nMAssay Description:Inhibition of HDAC2 (unknown origin) after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank
PDB3D3D Structure (crystal)

TargetHistone deacetylase 1(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50261819(5-(4-aminophenyl)-N-(5-(hydroxyamino)-5-oxopentyl)...)
Affinity DataIC50:  360nMAssay Description:Inhibition of HDAC1 (unknown origin) after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

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