Compile Data Set for Download or QSAR
maximum 50k data
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 2793
LigandPNGBDBM24705(4-aminopyrazolylpyrimidine analogue, 10k | 5-bromo...)
Affinity DataIC50:  6nMpH: 7.4 T: 22°CAssay Description:TrkA kinase activity was determined by measuring the kinase ability to phosphorylate synthetic tyrosine residues within a generic polypeptide substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM24706((2R)-2-({5-chloro-4-[(5-cyclopropyl-1H-pyrazol-3-y...)
Affinity DataIC50:  10nMpH: 7.4 T: 22°CAssay Description:TrkA kinase activity was determined by measuring the kinase ability to phosphorylate synthetic tyrosine residues within a generic polypeptide substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM24707((3S)-3-({5-chloro-4-[(5-cyclopropyl-1H-pyrazol-3-y...)
Affinity DataIC50:  13nMpH: 7.4 T: 22°CAssay Description:TrkA kinase activity was determined by measuring the kinase ability to phosphorylate synthetic tyrosine residues within a generic polypeptide substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM24708((3S)-3-({5-chloro-4-[(5-cyclopropyl-1H-pyrazol-3-y...)
Affinity DataIC50:  15nMpH: 7.4 T: 22°CAssay Description:TrkA kinase activity was determined by measuring the kinase ability to phosphorylate synthetic tyrosine residues within a generic polypeptide substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM24699(4-aminopyrazolylpyrimidine analogue, 10e | 5-bromo...)
Affinity DataIC50:  100nMpH: 7.4 T: 22°CAssay Description:TrkA kinase activity was determined by measuring the kinase ability to phosphorylate synthetic tyrosine residues within a generic polypeptide substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM24701(4-aminopyrazolylpyrimidine analogue, 10g | 5-bromo...)
Affinity DataIC50:  100nMpH: 7.4 T: 22°CAssay Description:TrkA kinase activity was determined by measuring the kinase ability to phosphorylate synthetic tyrosine residues within a generic polypeptide substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM24698(4-aminopyrazolylpyrimidine analogue, 10d | 5-bromo...)
Affinity DataIC50:  120nMpH: 7.4 T: 22°CAssay Description:TrkA kinase activity was determined by measuring the kinase ability to phosphorylate synthetic tyrosine residues within a generic polypeptide substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM24704((2R)-2-({5-bromo-4-[(5-cyclopropyl-1H-pyrazol-3-yl...)
Affinity DataIC50:  120nMpH: 7.4 T: 22°CAssay Description:TrkA kinase activity was determined by measuring the kinase ability to phosphorylate synthetic tyrosine residues within a generic polypeptide substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM24694(4-aminopyrazolylpyrimidine analogue, 5 | 5-bromo-4...)
Affinity DataIC50:  270nMpH: 7.4 T: 22°CAssay Description:TrkA kinase activity was determined by measuring the kinase ability to phosphorylate synthetic tyrosine residues within a generic polypeptide substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM24700(4-aminopyrazolylpyrimidine analogue, 10f | 5-bromo...)
Affinity DataIC50:  360nMpH: 7.4 T: 22°CAssay Description:TrkA kinase activity was determined by measuring the kinase ability to phosphorylate synthetic tyrosine residues within a generic polypeptide substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBDNF/NT-3 growth factors receptor(Human)
Astrazeneca

LigandPNGBDBM14824(4-({5-bromo-4-[(4-methoxyphenyl)amino]pyrimidin-2-...)
Affinity DataIC50:  646nMpH: 7.4 T: 22°CAssay Description:TrkB kinase activity was measured against its ability to phosphorylate synthetic tyrosine residues within a generic polypeptide substrate using homog...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM24702(4-aminopyrazolylpyrimidine analogue, 10h | 5-bromo...)
Affinity DataIC50:  650nMpH: 7.4 T: 22°CAssay Description:TrkA kinase activity was determined by measuring the kinase ability to phosphorylate synthetic tyrosine residues within a generic polypeptide substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM24696(4-aminopyrazolylpyrimidine analogue, 10b | 5-bromo...)
Affinity DataIC50:  720nMpH: 7.4 T: 22°CAssay Description:TrkA kinase activity was determined by measuring the kinase ability to phosphorylate synthetic tyrosine residues within a generic polypeptide substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM24695(2-N-benzyl-5-bromo-4-N-(5-cyclopropyl-1H-pyrazol-3...)
Affinity DataIC50:  750nMpH: 7.4 T: 22°CAssay Description:TrkA kinase activity was determined by measuring the kinase ability to phosphorylate synthetic tyrosine residues within a generic polypeptide substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBDNF/NT-3 growth factors receptor(Human)
Astrazeneca

LigandPNGBDBM24694(4-aminopyrazolylpyrimidine analogue, 5 | 5-bromo-4...)
Affinity DataIC50:  1.10E+3nMpH: 7.4 T: 22°CAssay Description:TrkB kinase activity was measured against its ability to phosphorylate synthetic tyrosine residues within a generic polypeptide substrate using homog...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM24697(4-aminopyrazolylpyrimidine analogue, 10c | 5-bromo...)
Affinity DataIC50:  1.17E+3nMpH: 7.4 T: 22°CAssay Description:TrkA kinase activity was determined by measuring the kinase ability to phosphorylate synthetic tyrosine residues within a generic polypeptide substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM24703((2S)-2-({5-bromo-4-[(5-cyclopropyl-1H-pyrazol-3-yl...)
Affinity DataIC50:  1.90E+3nMpH: 7.4 T: 22°CAssay Description:TrkA kinase activity was determined by measuring the kinase ability to phosphorylate synthetic tyrosine residues within a generic polypeptide substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed