Compile Data Set for Download or QSAR
maximum 50k data
Found 20 Enz. Inhib. hit(s) with all data for entry = 50038648
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50272893(1-(3-(1-ethyl-4-(1H-pyrrolo[2,3-b]pyridin-4-yl)-1H...)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of B-Raf by fluorescence anisotropy binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50272853(1-(3-(1-ethyl-4-(1H-pyrrolo[2,3-b]pyridin-4-yl)-1H...)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of B-Raf by fluorescence anisotropy binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50272855(1-(3-(1-ethyl-4-(1H-pyrrolo[2,3-b]pyridin-4-yl)-1H...)
Affinity DataIC50:  3.90nMAssay Description:Inhibition of B-Raf by fluorescence anisotropy binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50272817(1-(2-chlorophenyl)-3-(3-(1-ethyl-4-(1H-pyrrolo[2,3...)
Affinity DataIC50:  5.30nMAssay Description:Inhibition of B-Raf by fluorescence anisotropy binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50272892(1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(3-(1-eth...)
Affinity DataIC50:  5.40nMAssay Description:Inhibition of B-Raf by fluorescence anisotropy binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50272854(1-(3-chlorophenyl)-3-(3-(1-ethyl-4-(1H-pyrrolo[2,3...)
Affinity DataIC50:  10.5nMAssay Description:Inhibition of B-Raf by fluorescence anisotropy binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50272783(1-(3-(1-ethyl-4-(1H-pyrrolo[2,3-b]pyridin-4-yl)-1H...)
Affinity DataIC50:  17.4nMAssay Description:Inhibition of B-Raf by fluorescence anisotropy binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50272852(1-(2,6-difluorophenyl)-3-(3-(1-ethyl-4-(1H-pyrrolo...)
Affinity DataIC50:  25.7nMAssay Description:Inhibition of B-Raf by fluorescence anisotropy binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50377952(CHEMBL1964273)
Affinity DataIC50:  33.9nMAssay Description:Inhibition of B-Raf by fluorescence anisotropy binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50272814(1-cyclohexyl-3-(3-(1-ethyl-4-(1H-pyrrolo[2,3-b]pyr...)
Affinity DataIC50:  41.7nMAssay Description:Inhibition of B-Raf by fluorescence anisotropy binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50377951(CHEMBL1964274)
Affinity DataIC50:  45.7nMAssay Description:Inhibition of B-Raf by fluorescence anisotropy binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50272853(1-(3-(1-ethyl-4-(1H-pyrrolo[2,3-b]pyridin-4-yl)-1H...)
Affinity DataIC50:  63nMAssay Description:Inhibition of B-Raf-mediated phosphorylation of MEK1 in mouse 3T3 cells after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50272894(1-(3-(4-(3-bromo-1H-pyrrolo[2,3-b]pyridin-4-yl)-1-...)
Affinity DataIC50:  79.4nMAssay Description:Inhibition of B-Raf by fluorescence anisotropy binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50272816(1-(4-(benzyloxy)phenyl)-3-(3-(1-ethyl-4-(1H-pyrrol...)
Affinity DataIC50:  110nMAssay Description:Inhibition of B-Raf by fluorescence anisotropy binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50272815(1-benzyl-3-(3-(1-ethyl-4-(1H-pyrrolo[2,3-b]pyridin...)
Affinity DataIC50:  170nMAssay Description:Inhibition of B-Raf by fluorescence anisotropy binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50272893(1-(3-(1-ethyl-4-(1H-pyrrolo[2,3-b]pyridin-4-yl)-1H...)
Affinity DataIC50:  200nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50272893(1-(3-(1-ethyl-4-(1H-pyrrolo[2,3-b]pyridin-4-yl)-1H...)
Affinity DataIC50:  316nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50272782(1-(3-(1-ethyl-4-(1H-pyrrolo[2,3-b]pyridin-4-yl)-1H...)
Affinity DataIC50:  331nMAssay Description:Inhibition of B-Raf by fluorescence anisotropy binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50272853(1-(3-(1-ethyl-4-(1H-pyrrolo[2,3-b]pyridin-4-yl)-1H...)
Affinity DataIC50:  1.26E+3nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50272853(1-(3-(1-ethyl-4-(1H-pyrrolo[2,3-b]pyridin-4-yl)-1H...)
Affinity DataIC50:  5.01E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed