Compile Data Set for Download or QSAR
maximum 50k data
Found 54 Enz. Inhib. hit(s) with all data for entry = 50026752
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50273022(1-(2,3-dimethylphenyl)-N-(3-oxo-3,4-dihydro-2H-ben...)
Affinity DataKi:  28nMAssay Description:Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50273058(CHEMBL457186 | N-(3-oxo-3,4-dihydro-2H-benzo[b][1,...)
Affinity DataKi:  49nMAssay Description:Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50273024(1-(3,4-difluorophenyl)-N-(3-oxo-3,4-dihydro-2H-ben...)
Affinity DataKi:  56nMAssay Description:Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50272980(CHEMBL455958 | N-(3-oxo-3,4-dihydro-2H-benzo[b][1,...)
Affinity DataKi:  61nMAssay Description:Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50272856(CHEMBL497485 | N-(3-oxo-3,4-dihydro-2H-benzo[b][1,...)
Affinity DataKi:  65nMAssay Description:Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50272979(CHEMBL509968 | N-(3-oxo-3,4-dihydro-2H-benzo[b][1,...)
Affinity DataKi:  68nMAssay Description:Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50272900(1-(2-bromophenyl)-N-(3-oxo-3,4-dihydro-2H-benzo[b]...)
Affinity DataKi:  71nMAssay Description:Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50272982(1-(2-isopropylphenyl)-N-(3-oxo-3,4-dihydro-2H-benz...)
Affinity DataKi:  78nMAssay Description:Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50272983(1-(2-bromo-3-fluorophenyl)-N-(3-oxo-3,4-dihydro-2H...)
Affinity DataKi:  81nMAssay Description:Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50272858(1-(3-fluorophenyl)-N-(3-oxo-3,4-dihydro-2H-benzo[b...)
Affinity DataKi:  84nMAssay Description:Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50272899(1-(2-chlorophenyl)-N-(3-oxo-3,4-dihydro-2H-benzo[b...)
Affinity DataKi:  93nMAssay Description:Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50272859(1-(3-chlorophenyl)-N-(3-oxo-3,4-dihydro-2H-benzo[b...)
Affinity DataKi:  97nMAssay Description:Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50273021(1-(3-chloro-2-methylphenyl)-N-(3-oxo-3,4-dihydro-2...)
Affinity DataKi:  100nMAssay Description:Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50272981(1-(2-ethylphenyl)-N-(3-oxo-3,4-dihydro-2H-benzo[b]...)
Affinity DataKi:  125nMAssay Description:Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50273057(1-(3,5-difluorophenyl)-N-(3-oxo-3,4-dihydro-2H-ben...)
Affinity DataKi:  137nMAssay Description:Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50273023(1-(4-tert-butylphenyl)-N-(3-oxo-3,4-dihydro-2H-ben...)
Affinity DataKi:  142nMAssay Description:Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50272897(CHEMBL455926 | N-(3-oxo-3,4-dihydro-2H-benzo[b][1,...)
Affinity DataKi:  225nMAssay Description:Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50273025(1-(3,4-dimethylphenyl)-N-(3-oxo-3,4-dihydro-2H-ben...)
Affinity DataKi:  314nMAssay Description:Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50272898(1-(2-fluorophenyl)-N-(3-oxo-3,4-dihydro-2H-benzo[b...)
Affinity DataKi:  1.47E+3nMAssay Description:Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50273175(CHEMBL446545 | N-(2-(2-hydroxyethyl)-3-oxo-3,4-dih...)
Affinity DataIC50:  5nMAssay Description:Antagonist activity at human TRPV1 receptor assessed as inhibition of capsaicin-induced calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50273058(CHEMBL457186 | N-(3-oxo-3,4-dihydro-2H-benzo[b][1,...)
Affinity DataIC50:  59nMAssay Description:Antagonist activity at human TRPV1 receptor assessed as inhibition of capsaicin-induced calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50273022(1-(2,3-dimethylphenyl)-N-(3-oxo-3,4-dihydro-2H-ben...)
Affinity DataIC50:  60nMAssay Description:Antagonist activity at human TRPV1 receptor assessed as inhibition of capsaicin-induced calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50273023(1-(4-tert-butylphenyl)-N-(3-oxo-3,4-dihydro-2H-ben...)
Affinity DataIC50:  90nMAssay Description:Antagonist activity at human TRPV1 receptor assessed as inhibition of capsaicin-induced calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50273021(1-(3-chloro-2-methylphenyl)-N-(3-oxo-3,4-dihydro-2...)
Affinity DataIC50:  100nMAssay Description:Antagonist activity at human TRPV1 receptor assessed as inhibition of capsaicin-induced calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50272983(1-(2-bromo-3-fluorophenyl)-N-(3-oxo-3,4-dihydro-2H...)
Affinity DataIC50:  130nMAssay Description:Antagonist activity at human TRPV1 receptor assessed as inhibition of capsaicin-induced calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50272980(CHEMBL455958 | N-(3-oxo-3,4-dihydro-2H-benzo[b][1,...)
Affinity DataIC50:  150nMAssay Description:Antagonist activity at human TRPV1 receptor assessed as inhibition of capsaicin-induced calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50272981(1-(2-ethylphenyl)-N-(3-oxo-3,4-dihydro-2H-benzo[b]...)
Affinity DataIC50:  150nMAssay Description:Antagonist activity at human TRPV1 receptor assessed as inhibition of capsaicin-induced calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50272900(1-(2-bromophenyl)-N-(3-oxo-3,4-dihydro-2H-benzo[b]...)
Affinity DataIC50:  160nMAssay Description:Antagonist activity at human TRPV1 receptor assessed as inhibition of capsaicin-induced calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50272982(1-(2-isopropylphenyl)-N-(3-oxo-3,4-dihydro-2H-benz...)
Affinity DataIC50:  180nMAssay Description:Antagonist activity at human TRPV1 receptor assessed as inhibition of capsaicin-induced calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50272856(CHEMBL497485 | N-(3-oxo-3,4-dihydro-2H-benzo[b][1,...)
Affinity DataIC50:  180nMAssay Description:Antagonist activity at human TRPV1 receptor assessed as inhibition of capsaicin-induced calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50272859(1-(3-chlorophenyl)-N-(3-oxo-3,4-dihydro-2H-benzo[b...)
Affinity DataIC50:  190nMAssay Description:Antagonist activity at human TRPV1 receptor assessed as inhibition of capsaicin-induced calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50272899(1-(2-chlorophenyl)-N-(3-oxo-3,4-dihydro-2H-benzo[b...)
Affinity DataIC50:  220nMAssay Description:Antagonist activity at human TRPV1 receptor assessed as inhibition of capsaicin-induced calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50272820(CHEMBL498664 | N-(1H-indol-4-yl)-1-(3-(trifluorome...)
Affinity DataIC50:  230nMAssay Description:Antagonist activity at human TRPV1 receptor assessed as inhibition of capsaicin-induced calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50272860(1-(3-bromophenyl)-N-(3-oxo-3,4-dihydro-2H-benzo[b]...)
Affinity DataIC50:  330nMAssay Description:Antagonist activity at human TRPV1 receptor assessed as inhibition of capsaicin-induced calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50273057(1-(3,5-difluorophenyl)-N-(3-oxo-3,4-dihydro-2H-ben...)
Affinity DataIC50:  370nMAssay Description:Antagonist activity at human TRPV1 receptor assessed as inhibition of capsaicin-induced calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50273025(1-(3,4-dimethylphenyl)-N-(3-oxo-3,4-dihydro-2H-ben...)
Affinity DataIC50:  380nMAssay Description:Antagonist activity at human TRPV1 receptor assessed as inhibition of capsaicin-induced calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50272979(CHEMBL509968 | N-(3-oxo-3,4-dihydro-2H-benzo[b][1,...)
Affinity DataIC50:  380nMAssay Description:Antagonist activity at human TRPV1 receptor assessed as inhibition of capsaicin-induced calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50272897(CHEMBL455926 | N-(3-oxo-3,4-dihydro-2H-benzo[b][1,...)
Affinity DataIC50:  490nMAssay Description:Antagonist activity at human TRPV1 receptor assessed as inhibition of capsaicin-induced calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50272858(1-(3-fluorophenyl)-N-(3-oxo-3,4-dihydro-2H-benzo[b...)
Affinity DataIC50:  520nMAssay Description:Antagonist activity at human TRPV1 receptor assessed as inhibition of capsaicin-induced calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50272784(CHEMBL498653 | N-(quinolin-3-yl)-1-(3-(trifluorome...)
Affinity DataIC50:  600nMAssay Description:Antagonist activity at human TRPV1 receptor assessed as inhibition of capsaicin-induced calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50272898(1-(2-fluorophenyl)-N-(3-oxo-3,4-dihydro-2H-benzo[b...)
Affinity DataIC50:  670nMAssay Description:Antagonist activity at human TRPV1 receptor assessed as inhibition of capsaicin-induced calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50272818(CHEMBL497648 | N-(1-acetylindolin-6-yl)-1-(3-(trif...)
Affinity DataIC50:  800nMAssay Description:Antagonist activity at human TRPV1 receptor assessed as inhibition of capsaicin-induced calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50273024(1-(3,4-difluorophenyl)-N-(3-oxo-3,4-dihydro-2H-ben...)
Affinity DataIC50:  850nMAssay Description:Antagonist activity at human TRPV1 receptor assessed as inhibition of capsaicin-induced calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50273093(CHEMBL457196 | ethyl 2-methyl-3-oxo-6-(1-(3,4,5-tr...)
Affinity DataIC50:  870nMAssay Description:Antagonist activity at human TRPV1 receptor assessed as inhibition of capsaicin-induced calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50273129(CHEMBL514249 | methyl 2-(3-oxo-6-(1-(3,4,5-trifluo...)
Affinity DataIC50:  890nMAssay Description:Antagonist activity at human TRPV1 receptor assessed as inhibition of capsaicin-induced calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50272821(CHEMBL498665 | N-(1H-indol-5-yl)-1-(3-(trifluorome...)
Affinity DataIC50:  1.07E+3nMAssay Description:Antagonist activity at human TRPV1 receptor assessed as inhibition of capsaicin-induced calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50272896(1-(3-methoxyphenyl)-N-(3-oxo-3,4-dihydro-2H-benzo[...)
Affinity DataIC50:  1.42E+3nMAssay Description:Antagonist activity at human TRPV1 receptor assessed as inhibition of capsaicin-induced calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50272857(CHEMBL497486 | N-(3-oxo-3,4-dihydro-2H-benzo[b][1,...)
Affinity DataIC50:  1.81E+3nMAssay Description:Antagonist activity at human TRPV1 receptor assessed as inhibition of capsaicin-induced calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50273092(CHEMBL457195 | N-(3-oxo-3,4-dihydro-2H-benzo[b][1,...)
Affinity DataIC50:  1.96E+3nMAssay Description:Antagonist activity at human TRPV1 receptor assessed as inhibition of capsaicin-induced calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50273175(CHEMBL446545 | N-(2-(2-hydroxyethyl)-3-oxo-3,4-dih...)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibition of recombinant CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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