Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 50027007
TargetNeuropeptide Y receptor type 5(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50264364BDBM50264364(trans-4-[5-(4-Fluoro-phenyl)-1H-benzoimidazol-2-yl...)
Affinity DataIC50: 1.70nMAssay Description:Displacement of [125I]PYY from human recombinant NPYY5 receptor expressed in mouse LMtk cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50264493BDBM50264493(trans-4-[5-(5-Trifluoromethyl-[1,2,4]oxadiazol-3-y...)
Affinity DataIC50: 2.10nMAssay Description:Displacement of [125I]PYY from human recombinant NPYY5 receptor expressed in mouse LMtk cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50264395BDBM50264395(trans-4-(5-Chloro-6-phenyl-1H-benzoimidazol-2-yl)-...)
Affinity DataIC50: 2.20nMAssay Description:Displacement of [125I]PYY from human recombinant NPYY5 receptor expressed in mouse LMtk cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50264441BDBM50264441(trans-6-Chloro-2-(3'-oxo-3'H-spiro[cyclohex-1,1'-i...)
Affinity DataIC50: 2.20nMAssay Description:Displacement of [125I]PYY from human recombinant NPYY5 receptor expressed in mouse LMtk cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50264328BDBM50264328(trans-4-(5-Phenyl-1H-benzoimidazol-2-yl)-spiro[cyc...)
Affinity DataIC50: 2.30nMAssay Description:Displacement of [125I]PYY from human recombinant NPYY5 receptor expressed in mouse LMtk cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50264366BDBM50264366(trans-4-(5-Pyridin-2-yl-1H-benzoimidazol-2-yl)-spi...)
Affinity DataIC50: 2.40nMAssay Description:Displacement of [125I]PYY from human recombinant NPYY5 receptor expressed in mouse LMtk cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50264365BDBM50264365(trans-4-(5-Benzoyl-1H-benzoimidazol-2-yl)-spiro[cy...)
Affinity DataIC50: 2.40nMAssay Description:Displacement of [125I]PYY from human recombinant NPYY5 receptor expressed in mouse LMtk cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50264394BDBM50264394(trans-4-(5-Chloro-6-trifluoromethyl-1H-benzoimidaz...)
Affinity DataIC50: 2.60nMAssay Description:Displacement of [125I]PYY from human recombinant NPYY5 receptor expressed in mouse LMtk cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50264367BDBM50264367(trans-4-(5-Pyridin-3-yl-1H-benzoimidazol-2-yl)-spi...)
Affinity DataIC50: 3.10nMAssay Description:Displacement of [125I]PYY from human recombinant NPYY5 receptor expressed in mouse LMtk cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50264444BDBM50264444(trans-4-[5-(5-Methyl-[1,3,4]oxadiazol-2-yl)-1H-ben...)
Affinity DataIC50: 3.30nMAssay Description:Displacement of [125I]PYY from human recombinant NPYY5 receptor expressed in mouse LMtk cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50264442BDBM50264442(trans-4-Chloro-2-(3'-oxo-3'H-spiro[cyclohex-1,1'-i...)
Affinity DataIC50: 4.5nMAssay Description:Displacement of [125I]PYY from human recombinant NPYY5 receptor expressed in mouse LMtk cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50264492BDBM50264492(trans-4-[5-(5-Methyl-[1,2,4]oxadiazol-3-yl)-1H-ben...)
Affinity DataIC50: 5.10nMAssay Description:Displacement of [125I]PYY from human recombinant NPYY5 receptor expressed in mouse LMtk cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50264444BDBM50264444(trans-4-[5-(5-Methyl-[1,3,4]oxadiazol-2-yl)-1H-ben...)
Affinity DataIC50: 5.5nMAssay Description:Antagonist activity at human recombinant NPYY5 receptor expressed in mouse LMtk cells assessed as inhibition of NPY-induced calcium increaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50264494BDBM50264494(trans-4-[5-(2-Methyl-2H-tetrazol-5-yl)-1H-benzoimi...)
Affinity DataIC50: 5.90nMAssay Description:Displacement of [125I]PYY from human recombinant NPYY5 receptor expressed in mouse LMtk cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50264492BDBM50264492(trans-4-[5-(5-Methyl-[1,2,4]oxadiazol-3-yl)-1H-ben...)
Affinity DataIC50: 7nMAssay Description:Antagonist activity at human recombinant NPYY5 receptor expressed in mouse LMtk cells assessed as inhibition of NPY-induced calcium increaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50264494BDBM50264494(trans-4-[5-(2-Methyl-2H-tetrazol-5-yl)-1H-benzoimi...)
Affinity DataIC50: 7.20nMAssay Description:Antagonist activity at human recombinant NPYY5 receptor expressed in mouse LMtk cells assessed as inhibition of NPY-induced calcium increaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50264397BDBM50264397(trans-2-(3'-Oxo-3'H-spiro[cyclohex-1,1'-isobenzofu...)
Affinity DataIC50: 7.70nMAssay Description:Displacement of [125I]PYY from human recombinant NPYY5 receptor expressed in mouse LMtk cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50264393BDBM50264393(trans-4-(5,6-Dichloro-1H-benzoimidazol-2-yl)-spiro...)
Affinity DataIC50: 8nMAssay Description:Displacement of [125I]PYY from human recombinant NPYY5 receptor expressed in mouse LMtk cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50264443BDBM50264443(trans-4-(5-[1,3,4]Oxadiazol-2-yl-1H-benzoimidazol-...)
Affinity DataIC50: 15nMAssay Description:Displacement of [125I]PYY from human recombinant NPYY5 receptor expressed in mouse LMtk cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50264324BDBM50264324(trans-2-(3'-Oxo-3'H-spiro[cyclohex-1,1'-isobenzofu...)
Affinity DataIC50: 20nMAssay Description:Displacement of [125I]PYY from human recombinant NPYY5 receptor expressed in mouse LMtk cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50264325BDBM50264325(trans-4-(5-Chloro-1H-benzoimidazol-2-yl)-spiro[cyc...)
Affinity DataIC50: 39nMAssay Description:Displacement of [125I]PYY from human recombinant NPYY5 receptor expressed in mouse LMtk cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50264327BDBM50264327(trans-4-(5-Bromo-1H-benzoimidazol-2-yl)-spiro[cycl...)
Affinity DataIC50: 45nMAssay Description:Displacement of [125I]PYY from human recombinant NPYY5 receptor expressed in mouse LMtk cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50264326BDBM50264326(trans-4-(5-Trifluoromethyl-1H-benzoimidazol-2-yl)-...)
Affinity DataIC50: 47nMAssay Description:Displacement of [125I]PYY from human recombinant NPYY5 receptor expressed in mouse LMtk cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50264295BDBM50264295(trans-4-(1H-Benzoimidazol-2-yl)-spiro[cyclohexane-...)
Affinity DataIC50: 91nMAssay Description:Displacement of [125I]PYY from human recombinant NPYY5 receptor expressed in mouse LMtk cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50264396BDBM50264396(trans-4-(5,6-Dichloro-1-methyl-1H-benzoimidazol-2-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [125I]PYY from human recombinant NPYY5 receptor expressed in mouse LMtk cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50264495BDBM50264495(cis-6-Chloro-2-(3'-oxo-3'H-spiro[cyclohex-1,1'-iso...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [125I]PYY from human recombinant NPYY5 receptor expressed in mouse LMtk cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50264528BDBM50264528(cis-4-[5-(5-Methyl-[1,3,4]oxadiazol-2-yl)-1H-benzo...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [125I]PYY from human recombinant NPYY5 receptor expressed in mouse LMtk cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50264494BDBM50264494(trans-4-[5-(2-Methyl-2H-tetrazol-5-yl)-1H-benzoimi...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of NPYY1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50264494BDBM50264494(trans-4-[5-(2-Methyl-2H-tetrazol-5-yl)-1H-benzoimi...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of NPYY2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50264492BDBM50264492(trans-4-[5-(5-Methyl-[1,2,4]oxadiazol-3-yl)-1H-ben...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of NPYY1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 4(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50264494BDBM50264494(trans-4-[5-(2-Methyl-2H-tetrazol-5-yl)-1H-benzoimi...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of NPYY4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50264492BDBM50264492(trans-4-[5-(5-Methyl-[1,2,4]oxadiazol-3-yl)-1H-ben...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of NPYY2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 4(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50264492BDBM50264492(trans-4-[5-(5-Methyl-[1,2,4]oxadiazol-3-yl)-1H-ben...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of NPYY4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50264444BDBM50264444(trans-4-[5-(5-Methyl-[1,3,4]oxadiazol-2-yl)-1H-ben...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of NPYY1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 4(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50264444BDBM50264444(trans-4-[5-(5-Methyl-[1,3,4]oxadiazol-2-yl)-1H-ben...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of NPYY4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50264444BDBM50264444(trans-4-[5-(5-Methyl-[1,3,4]oxadiazol-2-yl)-1H-ben...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of NPYY2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed