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Report error Found 29 Enz. Inhib. hit(s) with all data for entry = 2798
LigandPNGBDBM24772(2-[(4-fluorophenyl)amino]-5-[5-({6-methoxy-7-[3-(m...)
Affinity DataKi:  3.40nM ΔG°:  -47.8kJ/molepH: 7.5 T: 22°CAssay Description:In vitro kinase assays were done to establish IC50 values against recombinant enzymes using homogeneous time-resolved fluorescence (HTRF) assay. For ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM24769(5-[3-fluoro-4-({6-methoxy-7-[3-(morpholin-4-yl)pro...)
Affinity DataKi:  4.90nM ΔG°:  -47.0kJ/molepH: 7.5 T: 22°CAssay Description:In vitro kinase assays were done to establish IC50 values against recombinant enzymes using homogeneous time-resolved fluorescence (HTRF) assay. For ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM24751(2-benzyl-5-[3-fluoro-4-({6-methoxy-7-[3-(morpholin...)
Affinity DataKi:  8.90nM ΔG°:  -45.5kJ/molepH: 7.5 T: 22°CAssay Description:In vitro kinase assays were done to establish IC50 values against recombinant enzymes using homogeneous time-resolved fluorescence (HTRF) assay. For ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

LigandPNGBDBM24754(2-benzyl-5-[3-fluoro-4-({6-methoxy-7-[3-(4-methylp...)
Affinity DataKi:  9.20nM ΔG°:  -45.4kJ/molepH: 7.5 T: 22°CAssay Description:In vitro kinase assays were done to establish IC50 values against recombinant enzymes using homogeneous time-resolved fluorescence (HTRF) assay. For ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM24764(5-[3-fluoro-4-({6-methoxy-7-[3-(morpholin-4-yl)pro...)
Affinity DataKi:  9.60nM ΔG°:  -45.3kJ/molepH: 7.5 T: 22°CAssay Description:In vitro kinase assays were done to establish IC50 values against recombinant enzymes using homogeneous time-resolved fluorescence (HTRF) assay. For ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM24752(2-benzyl-5-[3-fluoro-4-({6-methoxy-7-[3-(pyrrolidi...)
Affinity DataKi:  12nM ΔG°:  -44.8kJ/molepH: 7.5 T: 22°CAssay Description:In vitro kinase assays were done to establish IC50 values against recombinant enzymes using homogeneous time-resolved fluorescence (HTRF) assay. For ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM24768(5-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]-3-fluorophe...)
Affinity DataKi:  14nM ΔG°:  -44.4kJ/molepH: 7.5 T: 22°CAssay Description:In vitro kinase assays were done to establish IC50 values against recombinant enzymes using homogeneous time-resolved fluorescence (HTRF) assay. For ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

LigandPNGBDBM24765(5-[3-fluoro-4-({6-methoxy-7-[3-(morpholin-4-yl)pro...)
Affinity DataKi:  17nM ΔG°:  -43.9kJ/molepH: 7.5 T: 22°CAssay Description:In vitro kinase assays were done to establish IC50 values against recombinant enzymes using homogeneous time-resolved fluorescence (HTRF) assay. For ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM24755(2-benzyl-5-[4-({7-[3-(4-ethylpiperazin-1-yl)propox...)
Affinity DataKi:  21nM ΔG°:  -43.4kJ/molepH: 7.5 T: 22°CAssay Description:In vitro kinase assays were done to establish IC50 values against recombinant enzymes using homogeneous time-resolved fluorescence (HTRF) assay. For ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM24753(2-benzyl-5-[3-fluoro-4-({6-methoxy-7-[3-(1H-1,2,4-...)
Affinity DataKi:  29nM ΔG°:  -42.6kJ/molepH: 7.5 T: 22°CAssay Description:In vitro kinase assays were done to establish IC50 values against recombinant enzymes using homogeneous time-resolved fluorescence (HTRF) assay. For ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM24760(N-[(5-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]-3-fluor...)
Affinity DataKi:  30nM ΔG°:  -42.5kJ/molepH: 7.5 T: 22°CAssay Description:In vitro kinase assays were done to establish IC50 values against recombinant enzymes using homogeneous time-resolved fluorescence (HTRF) assay. For ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM24756(2-benzyl-5-[3-fluoro-4-({7-[3-(4-hydroxypiperidin-...)
Affinity DataKi:  33nM ΔG°:  -42.3kJ/molepH: 7.5 T: 22°CAssay Description:In vitro kinase assays were done to establish IC50 values against recombinant enzymes using homogeneous time-resolved fluorescence (HTRF) assay. For ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM24770(5-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]-3-fluorophe...)
Affinity DataKi:  38nM ΔG°:  -41.9kJ/molepH: 7.5 T: 22°CAssay Description:In vitro kinase assays were done to establish IC50 values against recombinant enzymes using homogeneous time-resolved fluorescence (HTRF) assay. For ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM24750(2-benzyl-5-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]-3-...)
Affinity DataKi:  39nM ΔG°:  -41.9kJ/molepH: 7.5 T: 22°CAssay Description:In vitro kinase assays were done to establish IC50 values against recombinant enzymes using homogeneous time-resolved fluorescence (HTRF) assay. For ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

LigandPNGBDBM24767(5-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]-3-fluorophe...)
Affinity DataKi:  45nM ΔG°:  -41.5kJ/molepH: 7.5 T: 22°CAssay Description:In vitro kinase assays were done to establish IC50 values against recombinant enzymes using homogeneous time-resolved fluorescence (HTRF) assay. For ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM24762(N-[(5-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]-3-fluor...)
Affinity DataKi:  52nM ΔG°:  -41.2kJ/molepH: 7.5 T: 22°CAssay Description:In vitro kinase assays were done to establish IC50 values against recombinant enzymes using homogeneous time-resolved fluorescence (HTRF) assay. For ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM24766(5-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]-3-fluorophe...)
Affinity DataKi:  63nM ΔG°:  -40.7kJ/molepH: 7.5 T: 22°CAssay Description:In vitro kinase assays were done to establish IC50 values against recombinant enzymes using homogeneous time-resolved fluorescence (HTRF) assay. For ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM24761(N-[(5-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]-3-fluor...)
Affinity DataKi:  71nM ΔG°:  -40.4kJ/molepH: 7.5 T: 22°CAssay Description:In vitro kinase assays were done to establish IC50 values against recombinant enzymes using homogeneous time-resolved fluorescence (HTRF) assay. For ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM24759(2-[amino(phenyl)methyl]-5-{4-[(6,7-dimethoxyquinol...)
Affinity DataKi:  72nM ΔG°:  -40.4kJ/molepH: 7.5 T: 22°CAssay Description:In vitro kinase assays were done to establish IC50 values against recombinant enzymes using homogeneous time-resolved fluorescence (HTRF) assay. For ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM24772(2-[(4-fluorophenyl)amino]-5-[5-({6-methoxy-7-[3-(m...)
Affinity DataKi:  83nM ΔG°:  -40.0kJ/molepH: 7.5 T: 22°CAssay Description:In vitro kinase assays were done to establish IC50 values against recombinant enzymes using homogeneous time-resolved fluorescence (HTRF) assay. For ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM24757(2-benzyl-5-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]-3-...)
Affinity DataKi:  107nM ΔG°:  -39.4kJ/molepH: 7.5 T: 22°CAssay Description:In vitro kinase assays were done to establish IC50 values against recombinant enzymes using homogeneous time-resolved fluorescence (HTRF) assay. For ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM24771(5-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]-3-fluorophe...)
Affinity DataKi:  136nM ΔG°:  -38.8kJ/molepH: 7.5 T: 22°CAssay Description:In vitro kinase assays were done to establish IC50 values against recombinant enzymes using homogeneous time-resolved fluorescence (HTRF) assay. For ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM24769(5-[3-fluoro-4-({6-methoxy-7-[3-(morpholin-4-yl)pro...)
Affinity DataKi:  139nM ΔG°:  -38.7kJ/molepH: 7.5 T: 22°CAssay Description:In vitro kinase assays were done to establish IC50 values against recombinant enzymes using homogeneous time-resolved fluorescence (HTRF) assay. For ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM24763(1-[(5-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]-3-fluor...)
Affinity DataKi:  368nM ΔG°:  -36.4kJ/molepH: 7.5 T: 22°CAssay Description:In vitro kinase assays were done to establish IC50 values against recombinant enzymes using homogeneous time-resolved fluorescence (HTRF) assay. For ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM24768(5-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]-3-fluorophe...)
Affinity DataKi:  382nM ΔG°:  -36.3kJ/molepH: 7.5 T: 22°CAssay Description:In vitro kinase assays were done to establish IC50 values against recombinant enzymes using homogeneous time-resolved fluorescence (HTRF) assay. For ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM24751(2-benzyl-5-[3-fluoro-4-({6-methoxy-7-[3-(morpholin...)
Affinity DataKi:  422nM ΔG°:  -36.0kJ/molepH: 7.5 T: 22°CAssay Description:In vitro kinase assays were done to establish IC50 values against recombinant enzymes using homogeneous time-resolved fluorescence (HTRF) assay. For ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM24758(2-benzyl-5-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]-3-...)
Affinity DataKi:  489nM ΔG°:  -35.7kJ/molepH: 7.5 T: 22°CAssay Description:In vitro kinase assays were done to establish IC50 values against recombinant enzymes using homogeneous time-resolved fluorescence (HTRF) assay. For ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM24750(2-benzyl-5-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]-3-...)
Affinity DataKi: >1.30E+3nM ΔG°: >-33.3kJ/molepH: 7.5 T: 22°CAssay Description:In vitro kinase assays were done to establish IC50 values against recombinant enzymes using homogeneous time-resolved fluorescence (HTRF) assay. For ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM24765(5-[3-fluoro-4-({6-methoxy-7-[3-(morpholin-4-yl)pro...)
Affinity DataKi: >3.00E+3nM ΔG°: >-31.2kJ/molepH: 7.5 T: 22°CAssay Description:In vitro kinase assays were done to establish IC50 values against recombinant enzymes using homogeneous time-resolved fluorescence (HTRF) assay. For ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed