Compile Data Set for Download or QSAR
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Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 50027127
TargetMu-type opioid receptor(Human)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50253754(4-(4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl)-N-m...)
Affinity DataKi:  0.600nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSigma non-opioid intracellular receptor 1(Rat)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50253754(4-(4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl)-N-m...)
Affinity DataKi:  0.800nMAssay Description:Displacement of [3H]Pentazocine from rat sigma 1 receptor in rat PC12 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlpha-2A adrenergic receptor(Human)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50253754(4-(4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl)-N-m...)
Affinity DataKi:  1nMAssay Description:Displacement of [125I]HEAT from adrenergic alpha2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetD(4) dopamine receptor(Human)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50253754(4-(4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl)-N-m...)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]N-methylspiperone from dopamine D4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistamine H2 receptor(Human)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50253754(4-(4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl)-N-m...)
Affinity DataKi:  1.70nMAssay Description:Displacement of [3H]tiotidine from human histamine H2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlpha-2C adrenergic receptor(Human)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50253754(4-(4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl)-N-m...)
Affinity DataKi:  2.40nMAssay Description:Displacement of [125I]HEAT from adrenergic Alpha-2C receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistamine H1 receptor(Human)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50253754(4-(4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl)-N-m...)
Affinity DataKi:  4.20nMAssay Description:Displacement of [3H]pyrilamine from human histamine H1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent serotonin transporter(Human)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50253754(4-(4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl)-N-m...)
Affinity DataKi:  6.20nMAssay Description:Displacement of [3H]citalopram from human SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlpha-2B adrenergic receptor(Human)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50253754(4-(4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl)-N-m...)
Affinity DataKi:  7nMAssay Description:Displacement of [125I]HEAT from adrenergic alpha2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistamine H3 receptor(Human)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50253754(4-(4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl)-N-m...)
Affinity DataKi:  9.30nMAssay Description:Displacement of [3H]alpha-methylhistamine from human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlpha-1A adrenergic receptor(Human)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50253754(4-(4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl)-N-m...)
Affinity DataKi:  9.90nMAssay Description:Displacement of [125I]HEAT from adrenergic alpha1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed