Compile Data Set for Download or QSAR
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Found 26 Enz. Inhib. hit(s) with all data for entry = 50027215
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50252860((S)-N-((S)-1,6-diamino-1-oxohexan-2-yl)-1-((S)-5-g...)
Affinity DataKi:  0.823nMAssay Description:Displacement of [3H]U69593 from kappa opioid receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50252855((4S,7S,13S)-13-[(S)-3-(4-Carbamoyl-2,6-dimethyl-ph...)
Affinity DataKi:  1.02nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50252864(CHEMBL454035 | antanal 2)
Affinity DataKi:  1.52nMAssay Description:Antagonist activity against mu opioid receptor in guinea pig ileum assessed as effect on TAPP-induced responseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50252856((4S,7S,13S)-13-[(S)-3-(4-Hydroxy-2,6-dimethyl-phen...)
Affinity DataKi:  2.23nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50252858((S)-2-({(4R,7S,13S)-7-(4-Fluoro-benzyl)-13-[(S)-3-...)
Affinity DataKi:  2.32nMAssay Description:Displacement of [3H]DSLET from delta opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50252863(CHEMBL507442 | antanal 1)
Affinity DataKi:  2.38nMAssay Description:Antagonist activity against mu opioid receptor in guinea pig ileum assessed as effect on TAPP-induced responseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50252857((S)-2-{[(4R,7S,13S)-13-[(S)-3-(4-Carbamoyl-2,6-dim...)
Affinity DataKi:  2.92nMAssay Description:Displacement of [3H]DSLET from delta opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50252856((4S,7S,13S)-13-[(S)-3-(4-Hydroxy-2,6-dimethyl-phen...)
Affinity DataKi:  3.61nMAssay Description:Displacement of [3H]DSLET from delta opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50252864(CHEMBL454035 | antanal 2)
Affinity DataKi:  7.74nMAssay Description:Antagonist activity against delta opioid receptor in mouse vas deference assessed as effect on DPDPE-induced responseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50252862((5S,8S,14R)-8-Benzyl-14-[(S)-2-[3-(4-hydroxy-2,6-d...)
Affinity DataKi:  15.5nMAssay Description:Antagonist activity against mu opioid receptor in guinea pig ileum assessed as effect on TAPP-induced responseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50252863(CHEMBL507442 | antanal 1)
Affinity DataKi:  17.4nMAssay Description:Antagonist activity against delta opioid receptor in mouse vas deference assessed as effect on DPDPE-induced responseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50252855((4S,7S,13S)-13-[(S)-3-(4-Carbamoyl-2,6-dimethyl-ph...)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]DSLET from delta opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50252859((S)-1-((S)-2-((2S,3S)-2-((S)-2-((S)-2-((S)-2-((S)-...)
Affinity DataKi:  26nMAssay Description:Displacement of [3H]U69593 from kappa opioid receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50252859((S)-1-((S)-2-((2S,3S)-2-((S)-2-((S)-2-((S)-2-((S)-...)
Affinity DataKi:  27.2nMAssay Description:Displacement of [3H]DSLET from delta opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50252859((S)-1-((S)-2-((2S,3S)-2-((S)-2-((S)-2-((S)-2-((S)-...)
Affinity DataKi:  29.6nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50252856((4S,7S,13S)-13-[(S)-3-(4-Hydroxy-2,6-dimethyl-phen...)
Affinity DataKi:  92.8nMAssay Description:Displacement of [3H]U69593 from kappa opioid receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50252860((S)-N-((S)-1,6-diamino-1-oxohexan-2-yl)-1-((S)-5-g...)
Affinity DataKi:  163nMAssay Description:Displacement of [3H]DSLET from delta opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50252855((4S,7S,13S)-13-[(S)-3-(4-Carbamoyl-2,6-dimethyl-ph...)
Affinity DataKi:  185nMAssay Description:Displacement of [3H]U69593 from kappa opioid receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50252860((S)-N-((S)-1,6-diamino-1-oxohexan-2-yl)-1-((S)-5-g...)
Affinity DataKi:  213nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50252862((5S,8S,14R)-8-Benzyl-14-[(S)-2-[3-(4-hydroxy-2,6-d...)
Affinity DataKi:  273nMAssay Description:Antagonist activity against delta opioid receptor in mouse vas deference assessed as effect on DPDPE-induced responseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50252858((S)-2-({(4R,7S,13S)-7-(4-Fluoro-benzyl)-13-[(S)-3-...)
Affinity DataKi:  406nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50252857((S)-2-{[(4R,7S,13S)-13-[(S)-3-(4-Carbamoyl-2,6-dim...)
Affinity DataKi:  3.65E+3nMAssay Description:Displacement of [3H]U69593 from kappa opioid receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50252858((S)-2-({(4R,7S,13S)-7-(4-Fluoro-benzyl)-13-[(S)-3-...)
Affinity DataKi:  3.71E+3nMAssay Description:Displacement of [3H]U69593 from kappa opioid receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50252857((S)-2-{[(4R,7S,13S)-13-[(S)-3-(4-Carbamoyl-2,6-dim...)
Affinity DataKi:  5.85E+3nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50252861(CHEMBL507214 | H-D-Phe-c[Cys-Tyr-DTrp-Orn-Thr-Pen]...)
Affinity DataIC50:  2.80nMAssay Description:Antagonist activity against mu opioid receptor in guinea pig ileum assessed as effect on TAPP-induced responseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50252861(CHEMBL507214 | H-D-Phe-c[Cys-Tyr-DTrp-Orn-Thr-Pen]...)
Affinity DataIC50:  1.35E+4nMAssay Description:Antagonist activity against delta opioid receptor in mouse vas deference assessed as effect on DPDPE-induced responseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed