Compile Data Set for Download or QSAR
Report error Found 53 Enz. Inhib. hit(s) with all data for entry = 50027294
TargetTyrosine-protein kinase ITK/TSK(Human)
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50274627(N-[1-(2-carbamoylethyl)-2-[(4-cyanobenzene)amido]-...)
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant ITK by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM26811(N-[2-benzamido-1-(2-carbamoylethyl)-2,3-dihydro-1H...)
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant ITK by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM26813(N-[(2E)-5-[benzene(methyl)amido]-1-(2-carbamoyleth...)
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant ITK by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50274471(N-(1-(3-amino-3-oxopropyl)-5-(N-methylcyclohexanec...)
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant ITK by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50274668(N-(1-(3-amino-3-oxopropyl)-2-(4-cyanobenzamido)-1H...)
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant ITK by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50274471(N-(1-(3-amino-3-oxopropyl)-5-(N-methylcyclohexanec...)
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant ITK by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM26812(CHEMBL485203 | N-[(2E)-5-[benzene(methyl)amido]-1-...)
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant ITK by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50274001(N-[5-(Benzoyl-ethyl-amino)-1-(2-carbamoyl-ethyl)-1...)
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant ITK by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50274666(N-[1-(2-carbamoylethyl)-2-[(4-cyanobenzene)amido]-...)
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant ITK by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50274154(N-(1-(3-amino-3-oxopropyl)-5-(4,4-difluoro-N-methy...)
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant ITK by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM26830(N-[(2E)-5-[benzene(methyl)amido]-1-(2-carbamoyleth...)
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant ITK by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50274000(N-(1-(3-amino-3-oxopropyl)-5-(N-methylbenzamido)-1...)
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant ITK by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM26827(CHEMBL458796 | N-[(2E)-5-[benzene(methyl)amido]-1-...)
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant ITK by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50274665(N-[1-(2-carbamoylethyl)-2-[(4-cyanobenzene)amido]-...)
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant ITK by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50274628(N-[1-(2-carbamoylethyl)-2-[(4-cyanobenzene)amido]-...)
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant ITK by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM26820(CHEMBL457886 | N-[(2E)-5-[benzene(methyl)amido]-1-...)
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant ITK by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50274003(N-[5-(Benzoyl-propyl-amino)-1-(2-carbamoyl-ethyl)-...)
Affinity DataIC50: 18nMAssay Description:Inhibition of recombinant ITK by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50274747(N-(1-(3-amino-3-oxopropyl)-5-(N-methylbenzamido)-1...)
Affinity DataIC50: 23nMAssay Description:Inhibition of recombinant ITK by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50274701(N-(1-(3-amino-3-oxopropyl)-2-(4-cyanobenzamido)-1H...)
Affinity DataIC50: 27nMAssay Description:Inhibition of recombinant ITK by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50274002(N-(1-(3-amino-3-oxopropyl)-5-(N-ethylbenzamido)-1H...)
Affinity DataIC50: 27nMAssay Description:Inhibition of recombinant ITK by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50274667(N-[1-(2-carbamoylethyl)-2-[(4-cyanobenzene)amido]-...)
Affinity DataIC50: 35nMAssay Description:Inhibition of recombinant ITK by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50274044(N-[5-(Benzoyl-propyl-amino)-1-(2-carbamoyl-ethyl)-...)
Affinity DataIC50: 54nMAssay Description:Inhibition of recombinant ITK by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM26820(CHEMBL457886 | N-[(2E)-5-[benzene(methyl)amido]-1-...)
Affinity DataIC50: 110nMAssay Description:Inhibition of IRKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM26811(N-[2-benzamido-1-(2-carbamoylethyl)-2,3-dihydro-1H...)
Affinity DataIC50: 120nMAssay Description:Inhibition of IRKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50274001(N-[5-(Benzoyl-ethyl-amino)-1-(2-carbamoyl-ethyl)-1...)
Affinity DataIC50: 160nMAssay Description:Inhibition of human ITK expressed in chicken DT40 cells assessed as B cell receptor-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50274628(N-[1-(2-carbamoylethyl)-2-[(4-cyanobenzene)amido]-...)
Affinity DataIC50: 260nMAssay Description:Inhibition of human ITK expressed in chicken DT40 cells assessed as B cell receptor-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase TXK(Human)
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50274001(N-[5-(Benzoyl-ethyl-amino)-1-(2-carbamoyl-ethyl)-1...)
Affinity DataIC50: 310nMAssay Description:Inhibition of TXKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50274000(N-(1-(3-amino-3-oxopropyl)-5-(N-methylbenzamido)-1...)
Affinity DataIC50: 320nMAssay Description:Inhibition of IRKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50274627(N-[1-(2-carbamoylethyl)-2-[(4-cyanobenzene)amido]-...)
Affinity DataIC50: 330nMAssay Description:Inhibition of human ITK expressed in chicken DT40 cells assessed as B cell receptor-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM26813(N-[(2E)-5-[benzene(methyl)amido]-1-(2-carbamoyleth...)
Affinity DataIC50: 340nMAssay Description:Inhibition of human ITK expressed in chicken DT40 cells assessed as B cell receptor-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM26812(CHEMBL485203 | N-[(2E)-5-[benzene(methyl)amido]-1-...)
Affinity DataIC50: 340nMAssay Description:Inhibition of human ITK expressed in chicken DT40 cells assessed as B cell receptor-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50274665(N-[1-(2-carbamoylethyl)-2-[(4-cyanobenzene)amido]-...)
Affinity DataIC50: 370nMAssay Description:Inhibition of human ITK expressed in chicken DT40 cells assessed as B cell receptor-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50274667(N-[1-(2-carbamoylethyl)-2-[(4-cyanobenzene)amido]-...)
Affinity DataIC50: 500nMAssay Description:Inhibition of human ITK expressed in chicken DT40 cells assessed as B cell receptor-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase TXK(Human)
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM26812(CHEMBL485203 | N-[(2E)-5-[benzene(methyl)amido]-1-...)
Affinity DataIC50: 500nMAssay Description:Inhibition of TXKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase TXK(Human)
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM26813(N-[(2E)-5-[benzene(methyl)amido]-1-(2-carbamoyleth...)
Affinity DataIC50: 560nMAssay Description:Inhibition of TXKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50274668(N-(1-(3-amino-3-oxopropyl)-2-(4-cyanobenzamido)-1H...)
Affinity DataIC50: 720nMAssay Description:Inhibition of human ITK expressed in chicken DT40 cells assessed as B cell receptor-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50274666(N-[1-(2-carbamoylethyl)-2-[(4-cyanobenzene)amido]-...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human ITK expressed in chicken DT40 cells assessed as B cell receptor-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50274704(N-[5-(Benzoyl-methyl-amino)-1-(2-carbamoyl-ethyl)-...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of recombinant ITK by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50274154(N-(1-(3-amino-3-oxopropyl)-5-(4,4-difluoro-N-methy...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human ITK expressed in chicken DT40 cells assessed as B cell receptor-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50274701(N-(1-(3-amino-3-oxopropyl)-2-(4-cyanobenzamido)-1H...)
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of human ITK expressed in chicken DT40 cells assessed as B cell receptor-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50274704(N-[5-(Benzoyl-methyl-amino)-1-(2-carbamoyl-ethyl)-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of IRKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50274001(N-[5-(Benzoyl-ethyl-amino)-1-(2-carbamoyl-ethyl)-1...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of IRKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM26812(CHEMBL485203 | N-[(2E)-5-[benzene(methyl)amido]-1-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of IRKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM26830(N-[(2E)-5-[benzene(methyl)amido]-1-(2-carbamoyleth...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of IRKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM26827(CHEMBL458796 | N-[(2E)-5-[benzene(methyl)amido]-1-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of IRKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50274747(N-(1-(3-amino-3-oxopropyl)-5-(N-methylbenzamido)-1...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of IRKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM26813(N-[(2E)-5-[benzene(methyl)amido]-1-(2-carbamoyleth...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of IRKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Tec(Human)
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM26813(N-[(2E)-5-[benzene(methyl)amido]-1-(2-carbamoyleth...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Tec kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lyn(Human)
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM26813(N-[(2E)-5-[benzene(methyl)amido]-1-(2-carbamoyleth...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of LynMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lyn(Human)
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM26812(CHEMBL485203 | N-[(2E)-5-[benzene(methyl)amido]-1-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of LynMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
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