Compile Data Set for Download or QSAR
maximum 50k data
Found 53 Enz. Inhib. hit(s) with all data for entry = 50027294
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50274627(CHEMBL483581 | N-[1-(2-carbamoylethyl)-2-[(4-cyano...)
Affinity DataIC50:  2nMAssay Description:Inhibition of recombinant ITK (unknown origin) by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM26811(CHEMBL485202 | N-[2-benzamido-1-(2-carbamoylethyl)...)
Affinity DataIC50:  3nMAssay Description:Inhibition of recombinant ITK (unknown origin) by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM26813(CHEMBL460824 | N-[(2E)-5-[benzene(methyl)amido]-1-...)
Affinity DataIC50:  3nMAssay Description:Inhibition of recombinant ITK (unknown origin) by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50274471(CHEMBL485556 | N-(1-(3-amino-3-oxopropyl)-5-(N-met...)
Affinity DataIC50:  4nMAssay Description:Inhibition of recombinant ITK (unknown origin) by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50274668(CHEMBL485030 | N-(1-(3-amino-3-oxopropyl)-2-(4-cya...)
Affinity DataIC50:  4nMAssay Description:Inhibition of recombinant ITK (unknown origin) by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50274471(CHEMBL485556 | N-(1-(3-amino-3-oxopropyl)-5-(N-met...)
Affinity DataIC50:  4nMAssay Description:Inhibition of recombinant ITK (unknown origin) by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM26812(CHEMBL485203 | N-[(2E)-5-[benzene(methyl)amido]-1-...)
Affinity DataIC50:  6nMAssay Description:Inhibition of recombinant ITK (unknown origin) by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50274666(CHEMBL485626 | N-[1-(2-carbamoylethyl)-2-[(4-cyano...)
Affinity DataIC50:  7nMAssay Description:Inhibition of recombinant ITK (unknown origin) by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50274001(CHEMBL462301 | N-[5-(Benzoyl-ethyl-amino)-1-(2-car...)
Affinity DataIC50:  7nMAssay Description:Inhibition of recombinant ITK (unknown origin) by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50274154(CHEMBL519033 | N-(1-(3-amino-3-oxopropyl)-5-(4,4-d...)
Affinity DataIC50:  8nMAssay Description:Inhibition of recombinant ITK (unknown origin) by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM26830(CHEMBL457706 | N-[(2E)-5-[benzene(methyl)amido]-1-...)
Affinity DataIC50:  8nMAssay Description:Inhibition of recombinant ITK (unknown origin) by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50274665(CHEMBL484945 | N-[1-(2-carbamoylethyl)-2-[(4-cyano...)
Affinity DataIC50:  10nMAssay Description:Inhibition of recombinant ITK (unknown origin) by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50274000(CHEMBL460389 | N-(1-(3-amino-3-oxopropyl)-5-(N-met...)
Affinity DataIC50:  10nMAssay Description:Inhibition of recombinant ITK (unknown origin) by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM26827(CHEMBL458796 | N-[(2E)-5-[benzene(methyl)amido]-1-...)
Affinity DataIC50:  10nMAssay Description:Inhibition of recombinant ITK (unknown origin) by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50274628(CHEMBL484766 | N-[1-(2-carbamoylethyl)-2-[(4-cyano...)
Affinity DataIC50:  12nMAssay Description:Inhibition of recombinant ITK (unknown origin) by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM26820(BMCL186218 Compound 1 | CHEMBL457886 | N-[(2E)-5-[...)
Affinity DataIC50:  14nMAssay Description:Inhibition of recombinant ITK (unknown origin) by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50274003(CHEMBL462514 | N-[5-(Benzoyl-propyl-amino)-1-(2-ca...)
Affinity DataIC50:  18nMAssay Description:Inhibition of recombinant ITK (unknown origin) by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50274747(CHEMBL457705 | N-(1-(3-amino-3-oxopropyl)-5-(N-met...)
Affinity DataIC50:  23nMAssay Description:Inhibition of recombinant ITK (unknown origin) by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50274701(CHEMBL485201 | N-(1-(3-amino-3-oxopropyl)-2-(4-cya...)
Affinity DataIC50:  27nMAssay Description:Inhibition of recombinant ITK (unknown origin) by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50274002(CHEMBL517901 | N-(1-(3-amino-3-oxopropyl)-5-(N-eth...)
Affinity DataIC50:  27nMAssay Description:Inhibition of recombinant ITK (unknown origin) by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50274667(CHEMBL490269 | N-[1-(2-carbamoylethyl)-2-[(4-cyano...)
Affinity DataIC50:  35nMAssay Description:Inhibition of recombinant ITK (unknown origin) by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50274044(CHEMBL485584 | N-[5-(Benzoyl-propyl-amino)-1-(2-ca...)
Affinity DataIC50:  54nMAssay Description:Inhibition of recombinant ITK (unknown origin) by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Homo sapiens (Human))
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM26820(BMCL186218 Compound 1 | CHEMBL457886 | N-[(2E)-5-[...)
Affinity DataIC50:  110nMAssay Description:Inhibition of IRKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Homo sapiens (Human))
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM26811(CHEMBL485202 | N-[2-benzamido-1-(2-carbamoylethyl)...)
Affinity DataIC50:  120nMAssay Description:Inhibition of IRKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50274001(CHEMBL462301 | N-[5-(Benzoyl-ethyl-amino)-1-(2-car...)
Affinity DataIC50:  160nMAssay Description:Inhibition of human ITK expressed in chicken DT40 cells assessed as B cell receptor-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50274628(CHEMBL484766 | N-[1-(2-carbamoylethyl)-2-[(4-cyano...)
Affinity DataIC50:  260nMAssay Description:Inhibition of human ITK expressed in chicken DT40 cells assessed as B cell receptor-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50274001(CHEMBL462301 | N-[5-(Benzoyl-ethyl-amino)-1-(2-car...)
Affinity DataIC50:  310nMAssay Description:Inhibition of TXKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Homo sapiens (Human))
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50274000(CHEMBL460389 | N-(1-(3-amino-3-oxopropyl)-5-(N-met...)
Affinity DataIC50:  320nMAssay Description:Inhibition of IRKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50274627(CHEMBL483581 | N-[1-(2-carbamoylethyl)-2-[(4-cyano...)
Affinity DataIC50:  330nMAssay Description:Inhibition of human ITK expressed in chicken DT40 cells assessed as B cell receptor-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM26812(CHEMBL485203 | N-[(2E)-5-[benzene(methyl)amido]-1-...)
Affinity DataIC50:  340nMAssay Description:Inhibition of human ITK expressed in chicken DT40 cells assessed as B cell receptor-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM26813(CHEMBL460824 | N-[(2E)-5-[benzene(methyl)amido]-1-...)
Affinity DataIC50:  340nMAssay Description:Inhibition of human ITK expressed in chicken DT40 cells assessed as B cell receptor-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50274665(CHEMBL484945 | N-[1-(2-carbamoylethyl)-2-[(4-cyano...)
Affinity DataIC50:  370nMAssay Description:Inhibition of human ITK expressed in chicken DT40 cells assessed as B cell receptor-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM26812(CHEMBL485203 | N-[(2E)-5-[benzene(methyl)amido]-1-...)
Affinity DataIC50:  500nMAssay Description:Inhibition of TXKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50274667(CHEMBL490269 | N-[1-(2-carbamoylethyl)-2-[(4-cyano...)
Affinity DataIC50:  500nMAssay Description:Inhibition of human ITK expressed in chicken DT40 cells assessed as B cell receptor-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM26813(CHEMBL460824 | N-[(2E)-5-[benzene(methyl)amido]-1-...)
Affinity DataIC50:  560nMAssay Description:Inhibition of TXKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50274668(CHEMBL485030 | N-(1-(3-amino-3-oxopropyl)-2-(4-cya...)
Affinity DataIC50:  720nMAssay Description:Inhibition of human ITK expressed in chicken DT40 cells assessed as B cell receptor-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50274666(CHEMBL485626 | N-[1-(2-carbamoylethyl)-2-[(4-cyano...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of human ITK expressed in chicken DT40 cells assessed as B cell receptor-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50274704(CHEMBL485206 | N-[5-(Benzoyl-methyl-amino)-1-(2-ca...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of recombinant ITK (unknown origin) by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50274154(CHEMBL519033 | N-(1-(3-amino-3-oxopropyl)-5-(4,4-d...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of human ITK expressed in chicken DT40 cells assessed as B cell receptor-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50274701(CHEMBL485201 | N-(1-(3-amino-3-oxopropyl)-2-(4-cya...)
Affinity DataIC50:  7.20E+3nMAssay Description:Inhibition of human ITK expressed in chicken DT40 cells assessed as B cell receptor-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Homo sapiens (Human))
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM26827(CHEMBL458796 | N-[(2E)-5-[benzene(methyl)amido]-1-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of IRKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Homo sapiens (Human))
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM26813(CHEMBL460824 | N-[(2E)-5-[benzene(methyl)amido]-1-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of IRKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Homo sapiens (Human))
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50274747(CHEMBL457705 | N-(1-(3-amino-3-oxopropyl)-5-(N-met...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of IRKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Homo sapiens (Human))
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM26830(CHEMBL457706 | N-[(2E)-5-[benzene(methyl)amido]-1-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of IRKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM26813(CHEMBL460824 | N-[(2E)-5-[benzene(methyl)amido]-1-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of LynMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Tec(Homo sapiens (Human))
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM26813(CHEMBL460824 | N-[(2E)-5-[benzene(methyl)amido]-1-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Tec kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Homo sapiens (Human))
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50274704(CHEMBL485206 | N-[5-(Benzoyl-methyl-amino)-1-(2-ca...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of IRKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50274001(CHEMBL462301 | N-[5-(Benzoyl-ethyl-amino)-1-(2-car...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of LynMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM26812(CHEMBL485203 | N-[(2E)-5-[benzene(methyl)amido]-1-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of LynMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Tec(Homo sapiens (Human))
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50274001(CHEMBL462301 | N-[5-(Benzoyl-ethyl-amino)-1-(2-car...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Tec kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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