Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 2864
TargetRho-associated protein kinase 2 [1-543,T431N](Human)
The Scripps Research Institute

LigandPNGBDBM25472(N-[4-(1H-pyrazol-4-yl)phenyl]-2,3-dihydro-1,4-benz...)
Affinity DataIC50: 1.5nMpH: 7.0 T: 2°CAssay Description:Assays were performed using the STK2 kinase system from Cisbio. Reaction mixture containing STK2 substrate, ATP and test compound was added to the we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2008
Entry Details Article
PubMed
TargetRho-associated protein kinase 2 [1-543,T431N](Human)
The Scripps Research Institute

LigandPNGBDBM25474(N-{2-[2-(dimethylamino)ethoxy]-4-(1H-pyrazol-4-yl)...)
Affinity DataIC50: 3.20nMpH: 7.0 T: 2°CAssay Description:Assays were performed using the STK2 kinase system from Cisbio. Reaction mixture containing STK2 substrate, ATP and test compound was added to the we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2008
Entry Details Article
PubMed
TargetRho-associated protein kinase 2 [1-543,T431N](Human)
The Scripps Research Institute

LigandPNGBDBM25473(N-[2-methoxy-4-(1H-pyrazol-4-yl)phenyl]-2,3-dihydr...)
Affinity DataIC50: 3.30nMpH: 7.0 T: 2°CAssay Description:Assays were performed using the STK2 kinase system from Cisbio. Reaction mixture containing STK2 substrate, ATP and test compound was added to the we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2008
Entry Details Article
PubMed
TargetRho-associated protein kinase 2 [1-543,T431N](Human)
The Scripps Research Institute

LigandPNGBDBM25470(cid_5056270 | N-[4-(pyridin-4-yl)-1,3-thiazol-2-yl...)
Affinity DataIC50: 7.20nMpH: 7.0 T: 2°CAssay Description:Assays were performed using the STK2 kinase system from Cisbio. Reaction mixture containing STK2 substrate, ATP and test compound was added to the we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2008
Entry Details Article
PubMed
TargetRho-associated protein kinase 2 [1-543,T431N](Human)
The Scripps Research Institute

LigandPNGBDBM25471(N-[4-(pyridin-4-yl)phenyl]-2,3-dihydro-1,4-benzodi...)
Affinity DataIC50: 46nMpH: 7.0 T: 2°CAssay Description:Assays were performed using the STK2 kinase system from Cisbio. Reaction mixture containing STK2 substrate, ATP and test compound was added to the we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2008
Entry Details Article
PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
The Scripps Research Institute

LigandPNGBDBM25472(N-[4-(1H-pyrazol-4-yl)phenyl]-2,3-dihydro-1,4-benz...)
Affinity DataIC50: 186nMpH: 7.3 T: 2°CAssay Description:Reaction mixture of kemptide, ATP, and test compound was added to the wells using a BioRAPTR FRD Workstation (Aurora Discovery). Reaction was started...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2008
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase MRCK alpha(Human)
The Scripps Research Institute

LigandPNGBDBM25473(N-[2-methoxy-4-(1H-pyrazol-4-yl)phenyl]-2,3-dihydr...)
Affinity DataIC50: 367nMpH: 7.3 T: 2°CAssay Description:The mixture of a S6-peptide, ATP, and test compound was added to the wells using a BioRAPTR FRD Workstation (Aurora Discovery). Reaction was started ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2008
Entry Details Article
PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
The Scripps Research Institute

LigandPNGBDBM25470(cid_5056270 | N-[4-(pyridin-4-yl)-1,3-thiazol-2-yl...)
Affinity DataIC50: 637nMpH: 7.3 T: 2°CAssay Description:Reaction mixture of kemptide, ATP, and test compound was added to the wells using a BioRAPTR FRD Workstation (Aurora Discovery). Reaction was started...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2008
Entry Details Article
PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
The Scripps Research Institute

LigandPNGBDBM25471(N-[4-(pyridin-4-yl)phenyl]-2,3-dihydro-1,4-benzodi...)
Affinity DataIC50: 692nMpH: 7.3 T: 2°CAssay Description:Reaction mixture of kemptide, ATP, and test compound was added to the wells using a BioRAPTR FRD Workstation (Aurora Discovery). Reaction was started...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2008
Entry Details Article
PubMed
TargetRho-associated protein kinase 2 [1-543,T431N](Human)
The Scripps Research Institute

LigandPNGBDBM25476(N-{2-[2-(dimethylamino)ethoxy]-4-(1H-pyrazol-4-yl)...)
Affinity DataIC50: 760nMpH: 7.0 T: 2°CAssay Description:Assays were performed using the STK2 kinase system from Cisbio. Reaction mixture containing STK2 substrate, ATP and test compound was added to the we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2008
Entry Details Article
PubMed
TargetRho-associated protein kinase 2 [1-543,T431N](Human)
The Scripps Research Institute

LigandPNGBDBM25475(2-[2-(dimethylamino)ethoxy]-4-(1H-pyrazol-4-yl)ani...)
Affinity DataIC50: 920nMpH: 7.0 T: 2°CAssay Description:Assays were performed using the STK2 kinase system from Cisbio. Reaction mixture containing STK2 substrate, ATP and test compound was added to the we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2008
Entry Details Article
PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
The Scripps Research Institute

LigandPNGBDBM25473(N-[2-methoxy-4-(1H-pyrazol-4-yl)phenyl]-2,3-dihydr...)
Affinity DataIC50: 940nMpH: 7.3 T: 2°CAssay Description:Reaction mixture of kemptide, ATP, and test compound was added to the wells using a BioRAPTR FRD Workstation (Aurora Discovery). Reaction was started...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2008
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase MRCK alpha(Human)
The Scripps Research Institute

LigandPNGBDBM25474(N-{2-[2-(dimethylamino)ethoxy]-4-(1H-pyrazol-4-yl)...)
Affinity DataIC50: 1.19E+3nMpH: 7.3 T: 2°CAssay Description:The mixture of a S6-peptide, ATP, and test compound was added to the wells using a BioRAPTR FRD Workstation (Aurora Discovery). Reaction was started ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2008
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase MRCK alpha(Human)
The Scripps Research Institute

LigandPNGBDBM25472(N-[4-(1H-pyrazol-4-yl)phenyl]-2,3-dihydro-1,4-benz...)
Affinity DataIC50: 1.19E+3nMpH: 7.3 T: 2°CAssay Description:The mixture of a S6-peptide, ATP, and test compound was added to the wells using a BioRAPTR FRD Workstation (Aurora Discovery). Reaction was started ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2008
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
The Scripps Research Institute

LigandPNGBDBM25472(N-[4-(1H-pyrazol-4-yl)phenyl]-2,3-dihydro-1,4-benz...)
Affinity DataIC50: 1.41E+3nMpH: 7.3 T: 2°CAssay Description:The mixture of a S6-peptide, ATP, and test compound was added to the wells using a BioRAPTR FRD Workstation (Aurora Discovery). Reaction was started ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2008
Entry Details Article
PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
The Scripps Research Institute

LigandPNGBDBM25474(N-{2-[2-(dimethylamino)ethoxy]-4-(1H-pyrazol-4-yl)...)
Affinity DataIC50: 3.97E+3nMpH: 7.3 T: 2°CAssay Description:Reaction mixture of kemptide, ATP, and test compound was added to the wells using a BioRAPTR FRD Workstation (Aurora Discovery). Reaction was started...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2008
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase MRCK alpha(Human)
The Scripps Research Institute

LigandPNGBDBM25470(cid_5056270 | N-[4-(pyridin-4-yl)-1,3-thiazol-2-yl...)
Affinity DataIC50: 4.85E+3nMpH: 7.3 T: 2°CAssay Description:The mixture of a S6-peptide, ATP, and test compound was added to the wells using a BioRAPTR FRD Workstation (Aurora Discovery). Reaction was started ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2008
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
The Scripps Research Institute

LigandPNGBDBM25471(N-[4-(pyridin-4-yl)phenyl]-2,3-dihydro-1,4-benzodi...)
Affinity DataIC50: 6.44E+3nMpH: 7.3 T: 2°CAssay Description:The mixture of a S6-peptide, ATP, and test compound was added to the wells using a BioRAPTR FRD Workstation (Aurora Discovery). Reaction was started ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2008
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase MRCK alpha(Human)
The Scripps Research Institute

LigandPNGBDBM25471(N-[4-(pyridin-4-yl)phenyl]-2,3-dihydro-1,4-benzodi...)
Affinity DataIC50: 7.05E+3nMpH: 7.3 T: 2°CAssay Description:The mixture of a S6-peptide, ATP, and test compound was added to the wells using a BioRAPTR FRD Workstation (Aurora Discovery). Reaction was started ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2008
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
The Scripps Research Institute

LigandPNGBDBM25474(N-{2-[2-(dimethylamino)ethoxy]-4-(1H-pyrazol-4-yl)...)
Affinity DataIC50: 7.49E+3nMpH: 7.3 T: 2°CAssay Description:The mixture of a S6-peptide, ATP, and test compound was added to the wells using a BioRAPTR FRD Workstation (Aurora Discovery). Reaction was started ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2008
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
The Scripps Research Institute

LigandPNGBDBM25473(N-[2-methoxy-4-(1H-pyrazol-4-yl)phenyl]-2,3-dihydr...)
Affinity DataIC50: 8.82E+3nMpH: 7.3 T: 2°CAssay Description:The mixture of a S6-peptide, ATP, and test compound was added to the wells using a BioRAPTR FRD Workstation (Aurora Discovery). Reaction was started ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2008
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
The Scripps Research Institute

LigandPNGBDBM25470(cid_5056270 | N-[4-(pyridin-4-yl)-1,3-thiazol-2-yl...)
Affinity DataIC50: 2.00E+4nMpH: 7.3 T: 2°CAssay Description:The mixture of a S6-peptide, ATP, and test compound was added to the wells using a BioRAPTR FRD Workstation (Aurora Discovery). Reaction was started ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2008
Entry Details Article
PubMed