Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 50027368
TargetEstrogen receptor beta(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50275964(4-{8-Fluoro-5-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl...)
Affinity DataIC50: 0.700nMAssay Description:Displacement of fluorescein labeled estradiol from human recombinant ERbeta expressed in baculovirus infected insect cells by fluorescence polarizati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50275861(4-{5-[4-(2-Pyrrolidin-1-yl-ethoxy)-phenyl]-2,3-dih...)
Affinity DataIC50: 1.90nMAssay Description:Displacement of fluorescein labeled estradiol from human recombinant ERalpha expressed in baculovirus infected insect cells by fluorescence polarizat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50275918(4-(4-Hydroxyphenyl)-5-[4-(2-pyrrolidin-1-yl-ethoxy...)
Affinity DataIC50: 2.90nMAssay Description:Displacement of fluorescein labeled estradiol from human recombinant ERbeta expressed in baculovirus infected insect cells by fluorescence polarizati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50275917(4-{8-Methoxy-5-[4-(2-piperidin-1-yl-ethoxy)-phenyl...)
Affinity DataIC50: 3.63nMAssay Description:Displacement of fluorescein labeled estradiol from human recombinant ERbeta expressed in baculovirus infected insect cells by fluorescence polarizati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50275916(4-{8-Methoxy-5-[4-(2-pyrrolidin-1-yl-ethoxy)-pheny...)
Affinity DataIC50: 4.61nMAssay Description:Displacement of fluorescein labeled estradiol from human recombinant ERbeta expressed in baculovirus infected insect cells by fluorescence polarizati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50276005([4-{8-Fluoro-4-[4-(2-pyrrolidin-1-yl-ethoxy)-pheny...)
Affinity DataIC50: 5.57nMAssay Description:Displacement of fluorescein labeled estradiol from human recombinant ERalpha expressed in baculovirus infected insect cells by fluorescence polarizat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50275861(4-{5-[4-(2-Pyrrolidin-1-yl-ethoxy)-phenyl]-2,3-dih...)
Affinity DataIC50: 5.90nMAssay Description:Displacement of fluorescein labeled estradiol from human recombinant ERbeta expressed in baculovirus infected insect cells by fluorescence polarizati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50275965(3-{8-Fluoro-5-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl...)
Affinity DataIC50: 6nMAssay Description:Displacement of fluorescein labeled estradiol from human recombinant ERbeta expressed in baculovirus infected insect cells by fluorescence polarizati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50276004(4-{8-Fluoro-5-[4-(2-piperidin-1-yl-ethoxy)-phenyl]...)
Affinity DataIC50: 6.5nMAssay Description:Displacement of fluorescein labeled estradiol from human recombinant ERalpha expressed in baculovirus infected insect cells by fluorescence polarizat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50275916(4-{8-Methoxy-5-[4-(2-pyrrolidin-1-yl-ethoxy)-pheny...)
Affinity DataIC50: 6.70nMAssay Description:Displacement of fluorescein labeled estradiol from human recombinant ERalpha expressed in baculovirus infected insect cells by fluorescence polarizat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50275918(4-(4-Hydroxyphenyl)-5-[4-(2-pyrrolidin-1-yl-ethoxy...)
Affinity DataIC50: 8.40nMAssay Description:Displacement of fluorescein labeled estradiol from human recombinant ERalpha expressed in baculovirus infected insect cells by fluorescence polarizat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50275860(1-{2-[4-(4-Phenyl-2,3-dihydro-benzo[b]oxepin-5-yl)...)
Affinity DataIC50: 8.77nMAssay Description:Displacement of fluorescein labeled estradiol from human recombinant ERalpha expressed in baculovirus infected insect cells by fluorescence polarizat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50276004(4-{8-Fluoro-5-[4-(2-piperidin-1-yl-ethoxy)-phenyl]...)
Affinity DataIC50: 8.78nMAssay Description:Displacement of fluorescein labeled estradiol from human recombinant ERbeta expressed in baculovirus infected insect cells by fluorescence polarizati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50275917(4-{8-Methoxy-5-[4-(2-piperidin-1-yl-ethoxy)-phenyl...)
Affinity DataIC50: 10.3nMAssay Description:Displacement of fluorescein labeled estradiol from human recombinant ERalpha expressed in baculovirus infected insect cells by fluorescence polarizat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50275964(4-{8-Fluoro-5-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl...)
Affinity DataIC50: 10.4nMAssay Description:Displacement of fluorescein labeled estradiol from human recombinant ERalpha expressed in baculovirus infected insect cells by fluorescence polarizat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50275965(3-{8-Fluoro-5-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl...)
Affinity DataIC50: 14nMAssay Description:Displacement of fluorescein labeled estradiol from human recombinant ERalpha expressed in baculovirus infected insect cells by fluorescence polarizat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50275919(1-{2-[4-(8-Fluoro-4-phenyl-2,3-dihydro-benzo[b]oxe...)
Affinity DataIC50: 16.2nMAssay Description:Displacement of fluorescein labeled estradiol from human recombinant ERalpha expressed in baculovirus infected insect cells by fluorescence polarizat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50276005([4-{8-Fluoro-4-[4-(2-pyrrolidin-1-yl-ethoxy)-pheny...)
Affinity DataIC50: 17.3nMAssay Description:Displacement of fluorescein labeled estradiol from human recombinant ERbeta expressed in baculovirus infected insect cells by fluorescence polarizati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM20608([3H]4-OHT | cid_449459 | CHEMBL489 | AFIMOXIFENE |...)
Affinity DataIC50: 20nMAssay Description:Displacement of fluorescein labeled estradiol from human recombinant ERbeta expressed in baculovirus infected insect cells by fluorescence polarizati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEstrogen receptor beta(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50275919(1-{2-[4-(8-Fluoro-4-phenyl-2,3-dihydro-benzo[b]oxe...)
Affinity DataIC50: 31nMAssay Description:Displacement of fluorescein labeled estradiol from human recombinant ERbeta expressed in baculovirus infected insect cells by fluorescence polarizati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM20608([3H]4-OHT | cid_449459 | CHEMBL489 | AFIMOXIFENE |...)
Affinity DataIC50: 40nMAssay Description:Displacement of fluorescein labeled estradiol from human recombinant ERalpha expressed in baculovirus infected insect cells by fluorescence polarizat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEstrogen receptor beta(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50275860(1-{2-[4-(4-Phenyl-2,3-dihydro-benzo[b]oxepin-5-yl)...)
Affinity DataIC50: 46.1nMAssay Description:Displacement of fluorescein labeled estradiol from human recombinant ERbeta expressed in baculovirus infected insect cells by fluorescence polarizati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM20607((2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}ethy...)
Affinity DataIC50: 70nMAssay Description:Displacement of fluorescein labeled estradiol from human recombinant ERalpha expressed in baculovirus infected insect cells by fluorescence polarizat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50275966(1-(2-{4-[8-Fluoro-4-(4-fluorophenyl)-2,3-dihydro-b...)
Affinity DataIC50: 126nMAssay Description:Displacement of fluorescein labeled estradiol from human recombinant ERalpha expressed in baculovirus infected insect cells by fluorescence polarizat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM20607((2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}ethy...)
Affinity DataIC50: 170nMAssay Description:Displacement of fluorescein labeled estradiol from human recombinant ERbeta expressed in baculovirus infected insect cells by fluorescence polarizati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50275966(1-(2-{4-[8-Fluoro-4-(4-fluorophenyl)-2,3-dihydro-b...)
Affinity DataIC50: 262nMAssay Description:Displacement of fluorescein labeled estradiol from human recombinant ERbeta expressed in baculovirus infected insect cells by fluorescence polarizati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEstrogen receptor(Rat)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50276006(Dimethyl-{2-[4-(4-thiophen-2-yl-2,3-dihydrobenzo[b...)
Affinity DataIC50: 828nMAssay Description:Displacement of [3H]estradiol from ERalpha in rat uteri cytosol by competitive radiometric binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEstrogen receptor beta(Rat)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50276006(Dimethyl-{2-[4-(4-thiophen-2-yl-2,3-dihydrobenzo[b...)
Affinity DataIC50: 828nMAssay Description:Displacement of [3H]estradiol from ERbeta receptor in rat uteri cytosol by competitive radiometric binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEstrogen receptor beta(Rat)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50276007(1-(2-{4-[4-(4-Methylbenzyl)-2,3-dihydro-benzo[b]ox...)
Affinity DataIC50: 1.42E+4nMAssay Description:Displacement of [3H]estradiol from ERbeta receptor in rat uteri cytosol by competitive radiometric binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEstrogen receptor(Rat)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50276007(1-(2-{4-[4-(4-Methylbenzyl)-2,3-dihydro-benzo[b]ox...)
Affinity DataIC50: 1.42E+4nMAssay Description:Displacement of [3H]estradiol from ERalpha in rat uteri cytosol by competitive radiometric binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50275967(1-(2-{4-[8-Fluoro-4-(4-methanesulfonyl-phenyl)-2,3...)
Affinity DataIC50: 1.50E+4nMAssay Description:Displacement of fluorescein labeled estradiol from human recombinant ERbeta expressed in baculovirus infected insect cells by fluorescence polarizati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50275967(1-(2-{4-[8-Fluoro-4-(4-methanesulfonyl-phenyl)-2,3...)
Affinity DataIC50: 1.50E+4nMAssay Description:Displacement of fluorescein labeled estradiol from human recombinant ERalpha expressed in baculovirus infected insect cells by fluorescence polarizat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed