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Found 26 Enz. Inhib. hit(s) with all data for entry = 50027415
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50275752(5-methyl-7-(3-(trifluoromethyl)phenyl)-N-(3,4,5-tr...)
Affinity DataIC50:  30nMAssay Description:Inhibition of PLK1 (unknown origin) expressed in baculovirus infected Trichoplusia ni cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK3(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50275752(5-methyl-7-(3-(trifluoromethyl)phenyl)-N-(3,4,5-tr...)
Affinity DataIC50:  30nMAssay Description:Inhibition of PLK3 (unknown origin) expressed in baculovirus infected Trichoplusia ni cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50275665(5-methyl-7-phenyl-N-(3,4,5-trimethoxyphenyl)imidaz...)
Affinity DataIC50:  40nMAssay Description:Inhibition of PLK1 (unknown origin) expressed in baculovirus infected Trichoplusia ni cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50275702(7-(3-bromophenyl)-5-methyl-N-(3,4,5-trimethoxyphen...)
Affinity DataIC50:  70nMAssay Description:Inhibition of PLK1 (unknown origin) expressed in baculovirus infected Trichoplusia ni cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50275806(7-(4-fluorophenyl)-5-methyl-N-(3,4,5-trimethoxyphe...)
Affinity DataIC50:  80nMAssay Description:Inhibition of PLK1 (unknown origin) expressed in baculovirus infected Trichoplusia ni cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK3(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50275665(5-methyl-7-phenyl-N-(3,4,5-trimethoxyphenyl)imidaz...)
Affinity DataIC50:  90nMAssay Description:Inhibition of PLK3 (unknown origin) expressed in baculovirus infected Trichoplusia ni cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50275664(CHEMBL521204 | N-(3,4-dimethoxyphenyl)-5-methyl-7-...)
Affinity DataIC50:  90nMAssay Description:Inhibition of PLK1 (unknown origin) expressed in baculovirus infected Trichoplusia ni cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50275665(5-methyl-7-phenyl-N-(3,4,5-trimethoxyphenyl)imidaz...)
Affinity DataIC50:  230nMAssay Description:Inhibition of CDK2/cyclin A (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50275626(CHEMBL487977 | N-(3-methoxyphenyl)-5-methyl-7-phen...)
Affinity DataIC50:  300nMAssay Description:Inhibition of PLK1 (unknown origin) expressed in baculovirus infected Trichoplusia ni cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50275628(CHEMBL520692 | N-(4-(2-(dimethylamino)ethoxy)pheny...)
Affinity DataIC50:  380nMAssay Description:Inhibition of PLK1 (unknown origin) expressed in baculovirus infected Trichoplusia ni cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50275754((3-(5-methyl-2-(3,4,5-trimethoxyphenylamino)imidaz...)
Affinity DataIC50:  410nMAssay Description:Inhibition of PLK1 (unknown origin) expressed in baculovirus infected Trichoplusia ni cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50275755(5-methyl-7-(3-phenoxyphenyl)-N-(3,4,5-trimethoxyph...)
Affinity DataIC50:  500nMAssay Description:Inhibition of PLK1 (unknown origin) expressed in baculovirus infected Trichoplusia ni cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50275627(CHEMBL519257 | N-(4-methoxyphenyl)-5-methyl-7-phen...)
Affinity DataIC50:  680nMAssay Description:Inhibition of PLK1 (unknown origin) expressed in baculovirus infected Trichoplusia ni cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50275753(5-methyl-7-(4-(trifluoromethyl)phenyl)-N-(3,4,5-tr...)
Affinity DataIC50:  1.06E+3nMAssay Description:Inhibition of PLK1 (unknown origin) expressed in baculovirus infected Trichoplusia ni cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50275625(5-methyl-N,7-diphenylimidazo[1,5-f][1,2,4]triazin-...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of PLK1 (unknown origin) expressed in baculovirus infected Trichoplusia ni cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50275589(CHEMBL519225 | N-benzyl-5-methyl-7-phenylimidazo[1...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of PLK1 (unknown origin) expressed in baculovirus infected Trichoplusia ni cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50275700(5-methyl-7-(2-nitrophenyl)-N-(3,4,5-trimethoxyphen...)
Affinity DataIC50:  1.98E+3nMAssay Description:Inhibition of PLK1 (unknown origin) expressed in baculovirus infected Trichoplusia ni cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50275701(7-(2-bromophenyl)-5-methyl-N-(3,4,5-trimethoxyphen...)
Affinity DataIC50:  2.67E+3nMAssay Description:Inhibition of PLK1 (unknown origin) expressed in baculovirus infected Trichoplusia ni cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50275663(4-(5-methyl-7-phenylimidazo[1,5-f][1,2,4]triazin-2...)
Affinity DataIC50:  2.74E+3nMAssay Description:Inhibition of PLK1 (unknown origin) expressed in baculovirus infected Trichoplusia ni cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50275662(5-methyl-N-(4-nitrophenyl)-7-phenylimidazo[1,5-f][...)
Affinity DataIC50:  2.81E+3nMAssay Description:Inhibition of PLK1 (unknown origin) expressed in baculovirus infected Trichoplusia ni cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50275699(7-(2-methoxyphenyl)-5-methyl-N-(3,4,5-trimethoxyph...)
Affinity DataIC50:  5.66E+3nMAssay Description:Inhibition of PLK1 (unknown origin) expressed in baculovirus infected Trichoplusia ni cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50275661(5-methyl-7-phenyl-N-(3-(trifluoromethyl)phenyl)imi...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PLK1 (unknown origin) expressed in baculovirus infected Trichoplusia ni cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50275590(5-methyl-7-phenylimidazo[1,5-f][1,2,4]triazin-2-am...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PLK1 (unknown origin) expressed in baculovirus infected Trichoplusia ni cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50275624(CHEMBL487776 | N-cyclohexyl-5-methyl-7-phenylimida...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PLK1 (unknown origin) expressed in baculovirus infected Trichoplusia ni cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50275592(5-methyl-N-(3-morpholinopropyl)-7-phenylimidazo[1,...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PLK1 (unknown origin) expressed in baculovirus infected Trichoplusia ni cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50275591(5-methyl-7-phenyl-N-(2-(pyridin-4-yl)ethyl)imidazo...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PLK1 (unknown origin) expressed in baculovirus infected Trichoplusia ni cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed