Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 50000761
TargetAromatase(Human)
UniversitäT Des Saarlandes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50009606BDBM50009606(5-Hydroxy-2-pyridin-4-ylmethyl-3,4-dihydro-2H-naph...)
Affinity DataIC50: 200nMAssay Description:In vitro inhibitory concentration against Aromatase was determined using [1-beta,2beta-3H]testosterone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAromatase(Human)
UniversitäT Des Saarlandes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50009606BDBM50009606(5-Hydroxy-2-pyridin-4-ylmethyl-3,4-dihydro-2H-naph...)
Affinity DataIC50: 210nMAssay Description:In vitro inhibitory concentration against Aromatase was determined using [1-beta,2beta-3H]testosterone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAromatase(Human)
UniversitäT Des Saarlandes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50009606BDBM50009606(5-Hydroxy-2-pyridin-4-ylmethyl-3,4-dihydro-2H-naph...)
Affinity DataIC50: 210nMAssay Description:In vitro inhibitory concentration against human placental Cytochrome P450 19A was determined using [1-beta,2beta-3H]testosterone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAromatase(Human)
UniversitäT Des Saarlandes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50009607BDBM50009607(CHEMBL92488 | 5-hydroxy-2-(pyridin-4-ylmethylene)-...)
Affinity DataIC50: 690nMAssay Description:In vitro inhibitory concentration against human placental Cytochrome P450 19A was determined using [1-beta,2beta-3H]testosterone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAromatase(Rat)
UniversitäT Des Saarlandes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50009606BDBM50009606(5-Hydroxy-2-pyridin-4-ylmethyl-3,4-dihydro-2H-naph...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of rat ovarian Cytochrome P450 19AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAromatase(Human)
UniversitäT Des Saarlandes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50009618BDBM50009618(CHEMBL90427 | 5-Methoxy-2-pyridin-4-ylmethyl-3,4-d...)
Affinity DataIC50: 2.20E+3nMAssay Description:In vitro inhibitory concentration against human placental Cytochrome P450 19A was determined using [1-beta,2beta-3H]testosterone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAromatase(Human)
UniversitäT Des Saarlandes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50009616BDBM50009616(CHEMBL313774 | 7-Hydroxy-2-pyridin-4-ylmethylene-3...)
Affinity DataIC50: 3.00E+3nMAssay Description:In vitro inhibitory concentration against human placental Cytochrome P450 19A was determined using [1-beta,2beta-3H]testosterone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAromatase(Human)
UniversitäT Des Saarlandes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50009608BDBM50009608(CHEMBL88233 | 6-Methoxy-2-pyridin-4-ylmethyl-3,4-d...)
Affinity DataIC50: 3.30E+3nMAssay Description:In vitro inhibitory concentration against human placental Cytochrome P450 19A was determined using [1-beta,2beta-3H]testosterone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAromatase(Human)
UniversitäT Des Saarlandes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50009614BDBM50009614(CHEMBL92065 | 2-Pyridin-4-ylmethyl-3,4-dihydro-2H-...)
Affinity DataIC50: 4.30E+3nMAssay Description:In vitro inhibitory concentration against human placental Cytochrome P450 19A was determined using [1-beta,2beta-3H]testosterone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAromatase(Human)
UniversitäT Des Saarlandes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50009615BDBM50009615(CHEMBL90077 | 7-Hydroxy-2-pyridin-4-ylmethyl-3,4-d...)
Affinity DataIC50: 4.90E+3nMAssay Description:In vitro inhibitory concentration against human placental Cytochrome P450 19A was determined using [1-beta,2beta-3H]testosterone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAromatase(Human)
UniversitäT Des Saarlandes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50009617BDBM50009617(CHEMBL91818 | 6-Hydroxy-2-pyridin-4-ylmethyl-3,4-d...)
Affinity DataIC50: 6.20E+3nMAssay Description:In vitro inhibitory concentration against human placental Cytochrome P450 19A was determined using [1-beta,2beta-3H]testosterone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAromatase(Human)
UniversitäT Des Saarlandes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50009612BDBM50009612(CHEMBL91101 | 5-Methoxy-2-pyridin-4-ylmethylene-3,...)
Affinity DataIC50: 6.30E+3nMAssay Description:In vitro inhibitory concentration against human placental Cytochrome P450 19A was determined using [1-beta,2beta-3H]testosterone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAromatase(Rat)
UniversitäT Des Saarlandes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50009618BDBM50009618(CHEMBL90427 | 5-Methoxy-2-pyridin-4-ylmethyl-3,4-d...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of rat ovarian Cytochrome P450 19AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAromatase(Human)
UniversitäT Des Saarlandes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50009609BDBM50009609(6-hydroxy-2-(pyridin-4-ylmethylene)-3,4-dihydronap...)
Affinity DataIC50: 8.60E+3nMAssay Description:In vitro inhibitory concentration against human placental Cytochrome P450 19A was determined using [1-beta,2beta-3H]testosterone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAromatase(Human)
UniversitäT Des Saarlandes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50009610BDBM50009610(CHEMBL328217 | 6-methoxy-2-(pyridin-4-ylmethylene)...)
Affinity DataIC50: 8.90E+3nMAssay Description:In vitro inhibitory concentration against human placental Cytochrome P450 19A was determined using [1-beta,2beta-3H]testosterone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAromatase(Human)
UniversitäT Des Saarlandes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50009605BDBM50009605(CHEMBL90585 | 2-(pyridin-4-ylmethylene)-3,4-dihydr...)
Affinity DataIC50: 9.30E+3nMAssay Description:In vitro inhibitory concentration against human placental Cytochrome P450 19A was determined using [1-beta,2beta-3H]testosterone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAromatase(Human)
UniversitäT Des Saarlandes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50009613BDBM50009613(CHEMBL93666 | 7-Methoxy-2-pyridin-4-ylmethyl-3,4-d...)
Affinity DataIC50: 9.60E+3nMAssay Description:In vitro inhibitory concentration against human placental Cytochrome P450 19A was determined using [1-beta,2beta-3H]testosterone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAromatase(Human)
UniversitäT Des Saarlandes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50009613BDBM50009613(CHEMBL93666 | 7-Methoxy-2-pyridin-4-ylmethyl-3,4-d...)
Affinity DataIC50: 9.60E+3nMAssay Description:In vitro inhibitory concentration against Aromatase was determined using [1-beta,2beta-3H]testosterone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAromatase(Human)
UniversitäT Des Saarlandes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50009613BDBM50009613(CHEMBL93666 | 7-Methoxy-2-pyridin-4-ylmethyl-3,4-d...)
Affinity DataIC50: 9.60E+3nMAssay Description:In vitro inhibitory concentration against Aromatase was determined using [1-beta,2beta-3H]testosterone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAromatase(Human)
UniversitäT Des Saarlandes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50009611BDBM50009611(CHEMBL419131 | 7-Methoxy-2-pyridin-4-ylmethylene-3...)
Affinity DataIC50: 1.30E+4nMAssay Description:In vitro inhibitory concentration against human placental Cytochrome P450 19A was determined using [1-beta,2beta-3H]testosterone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAromatase(Rat)
UniversitäT Des Saarlandes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 9460BDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | C...)
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of rat ovarian Cytochrome P450 19AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAromatase(Human)
UniversitäT Des Saarlandes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 9460BDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | C...)
Affinity DataIC50: 3.70E+4nMAssay Description:In vitro inhibitory concentration against human placental Cytochrome P450 19A was determined using [1-beta,2beta-3H]testosterone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAromatase(Human)
UniversitäT Des Saarlandes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 9460BDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | C...)
Affinity DataIC50: 3.70E+4nMAssay Description:In vitro inhibitory concentration against human placental Cytochrome P450 19A was determined using [1-beta,2beta-3H]testosterone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed