Compile Data Set for Download or QSAR
maximum 50k data
Found 15 Enz. Inhib. hit(s) with all data for entry = 2958
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM26359((2Z)-3-[(3-chloro-1H-indol-7-yl)amino]-2-cyano-N,N...)
Affinity DataIC50:  2.40nMpH: 7.4 T: 2°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM26357(3-chloroindole compound, 18 | methyl (2Z)-3-[(3-ch...)
Affinity DataIC50:  8.90nMpH: 7.4 T: 2°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM26360((2Z)-3-[(3-bromo-1H-indol-7-yl)amino]-2-cyano-N,N-...)
Affinity DataIC50:  9nMpH: 7.4 T: 2°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM26354(2-{[(3-chloro-1H-indol-7-yl)amino]({[(3S)-2-oxo-1-...)
Affinity DataIC50:  9.30nMpH: 7.4 T: 2°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM26351(2-methylbenzofuran compound, 2 | 2-{[(2-methyl-1-b...)
Affinity DataIC50:  30nMpH: 7.4 T: 2°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM26364((3S)-1-(3-chloro-1H-indol-7-yl)-2-cyano-2-oxo-1-[2...)
Affinity DataIC50:  46nMpH: 7.4 T: 2°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM26350((S)-1-(2-oxo-1-(2-oxo-2-(pyrrolidin-1-yl)ethyl)aze...)
Affinity DataIC50:  110nMpH: 7.4 T: 2°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM26352(2-{[(3-methyl-1H-indol-7-yl)amino]({[(3S)-2-oxo-1-...)
Affinity DataIC50:  114nMpH: 7.4 T: 2°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM26358((2Z)-2-cyano-N,N-dimethyl-3-[(3-methyl-1H-indol-7-...)
Affinity DataIC50:  118nMpH: 7.4 T: 2°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM26361((2Z)-2-cyano-3-[(3-cyano-1H-indol-7-yl)amino]-N,N-...)
Affinity DataIC50:  290nMpH: 7.4 T: 2°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM26363((3S)-2-cyano-1-(3-methyl-1H-indol-7-yl)-2-oxo-1-[2...)
Affinity DataIC50:  336nMpH: 7.4 T: 2°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM26353(2-[(1H-indol-7-ylamino)({[(3S)-2-oxo-1-[2-oxo-2-(p...)
Affinity DataIC50:  430nMpH: 7.4 T: 2°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM26355(indole-7-yl compound, 16 | methyl (2Z)-2-cyano-3-(...)
Affinity DataIC50:  650nMpH: 7.4 T: 2°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM26356(indazol-7-yl compound, 17 | methyl (2Z)-2-cyano-3-...)
Affinity DataIC50:  1.37E+4nMpH: 7.4 T: 2°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM26362(3-carboxamide indole compound, 23 | 7-{[(1Z)-2-cya...)
Affinity DataIC50:  1.70E+4nMpH: 7.4 T: 2°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed