Affinity DataKi: 4.00E+3nMAssay Description:Binding affinity to Hsp90 by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of Hsp90 in human MCF7 cells assessed as Her2 degradationMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of Hsp90 in human MCF7 cells assessed as Her2 degradationMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of Hsp90 assessed as Her2 degradation by cell based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Binding affinity to Hsp90 by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Binding affinity to Hsp90 by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition of Hsp90 in human MCF7 cells assessed as Her2 degradationMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Binding affinity to Hsp90 by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of Hsp90 in human MCF7 cells assessed as Her2 degradationMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of Hsp90 in human MCF7 cells assessed as Her2 degradationMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of Hsp90 assessed as Her2 degradation by cell based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Binding affinity to Hsp90 by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Affinity DataIC50: 31nMAssay Description:Inhibition of Her2 in human SKBR3 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Binding affinity to Hsp90 in human SKBR3 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Inhibition of Hsp90 in human SKBR3 cells assessed as Her2 degradationMore data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Inhibition of Hsp90 in human MCF7 cells assessed as Her2 degradationMore data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of Hsp90 in human MCF7 cells assessed as Her2 degradationMore data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of Hsp90 in human MCF7 cells assessed as Her2 degradationMore data for this Ligand-Target Pair
Affinity DataIC50: 180nMAssay Description:Inhibition of Hsp90 in human MCF7 cells assessed as Her2 degradationMore data for this Ligand-Target Pair
Affinity DataIC50: 280nMAssay Description:Inhibition of Hsp90 assessed as Her2 degradation by cell based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of Hsp90 in human SKBR3 cells assessed as Her2 degradationMore data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Binding affinity to Hsp90 by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 700nMAssay Description:Binding affinity to Hsp90 by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 740nMAssay Description:Binding affinity to Hsp90 by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Hsp90 in human MCF7 cells assessed as Her2 degradationMore data for this Ligand-Target Pair
TargetATP-dependent molecular chaperone HSP82(Baker's yeast)
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Affinity DataIC50: 8.90E+3nMAssay Description:Binding affinity to yeast Hsp90 ATPase activityMore data for this Ligand-Target Pair
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of Hsp90More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Binding affinity to Hsp90 ATPase activity in human MCF7 cellsMore data for this Ligand-Target Pair
Affinity DataKd: 16nMAssay Description:Binding affinity to Hsp90 in human SKBR3 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 22nMAssay Description:Binding affinity to Hsp90 by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataEC50: 50nMAssay Description:Inhibition of Hsp90 in human SKBR3 cells assessed as Her2 degradationMore data for this Ligand-Target Pair
TargetATP-dependent molecular chaperone HSP82(Baker's yeast)
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Affinity DataKd: 1.20E+3nMAssay Description:Binding affinity to N-terminal ATP/ADP-binding domain of yeast Hsp90More data for this Ligand-Target Pair
Affinity DataKd: 280nMAssay Description:Inhibition of Hsp90 by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKd: 680nMAssay Description:Inhibition of Hsp90 by surface plasmon resonance assayMore data for this Ligand-Target Pair
TargetATP-dependent molecular chaperone HSP82(Baker's yeast)
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Affinity DataKd: 19nMAssay Description:Binding affinity to N-terminal ATP/ADP-binding domain of yeast Hsp90More data for this Ligand-Target Pair
Affinity DataEC50: 1.50E+4nMAssay Description:Inhibition of Hsp90More data for this Ligand-Target Pair
Affinity DataEC50: 1.00E+3nMAssay Description:Inhibition of Hsp90More data for this Ligand-Target Pair