Compile Data Set for Download or QSAR
maximum 50k data
Found 6 Enz. Inhib. hit(s) with all data for entry = 50027818
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50266017(5-(3,5-di-tert-butyl-4-hydroxyphenyl)-3H-1,2-dithi...)
Affinity DataIC50:  7.20nMAssay Description:Inhibition of human recombinant COX2 expressed in Sf21 cells assessed as effect on prostaglandin E2 production by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  28nMAssay Description:Inhibition of human platelet COX1 assessed as effect on prostaglandin E2 production by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50266016(5-(3,5-di-tert-butyl-4-methoxyphenyl)-3H-1,2-dithi...)
Affinity DataIC50:  47nMAssay Description:Inhibition of human recombinant COX2 expressed in Sf21 cells assessed as effect on prostaglandin E2 production by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM22369(4-(4-methanesulfonylphenyl)-3-phenyl-2,5-dihydrofu...)
Affinity DataIC50:  75nMAssay Description:Inhibition of human recombinant COX2 expressed in Sf21 cells assessed as effect on prostaglandin E2 production by ELISAMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50266017(5-(3,5-di-tert-butyl-4-hydroxyphenyl)-3H-1,2-dithi...)
Affinity DataIC50:  3.64E+3nMAssay Description:Inhibition of human platelet COX1 assessed as effect on prostaglandin E2 production by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50266016(5-(3,5-di-tert-butyl-4-methoxyphenyl)-3H-1,2-dithi...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human platelet COX1 assessed as effect on prostaglandin E2 production by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed