Compile Data Set for Download or QSAR
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Found 18 Enz. Inhib. hit(s) with all data for entry = 50038715
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50160248((2S,3S)-2-[alpha-(2-Methylphenylthio)phenylmethyl]...)
Affinity DataKi:  0.300nMAssay Description:Displacement of [3H]nisoxetine from human NET receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50199005((S)-2-((S)-(2-methoxyphenoxy)(phenyl)methyl)morpho...)
Affinity DataKi:  0.950nMAssay Description:Displacement of [3H]nisoxetine from human NET receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50254209((2S,3S)-2-[alpha-(2-Methylphenoxy)phenylmethyl]mor...)
Affinity DataKi:  1.02nMAssay Description:Displacement of [3H]nisoxetine from human NET receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50370475(S,S-REBOXETINE)
Affinity DataKi:  1.04nMAssay Description:Displacement of [3H]nisoxetine from human NET receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50254210((2S,3S)-2-[alpha-(2-(2-Fluoroethyl)phenoxy)phenylm...)
Affinity DataKi:  3.14nMAssay Description:Displacement of [3H]nisoxetine from human NET receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50254211((2S,3S)-2-[alpha-(2-(3-Fluoropropyl)phenoxy)phenyl...)
Affinity DataKi:  3.68nMAssay Description:Displacement of [3H]nisoxetine from human NET receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50160248((2S,3S)-2-[alpha-(2-Methylphenylthio)phenylmethyl]...)
Affinity DataKi:  14.8nMAssay Description:Displacement of [3H]citalopram from human SERT receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50254209((2S,3S)-2-[alpha-(2-Methylphenoxy)phenylmethyl]mor...)
Affinity DataKi:  93nMAssay Description:Displacement of [3H]citalopram from human SERT receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50199005((S)-2-((S)-(2-methoxyphenoxy)(phenyl)methyl)morpho...)
Affinity DataKi:  185nMAssay Description:Displacement of [3H]citalopram from human SERT receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50160248((2S,3S)-2-[alpha-(2-Methylphenylthio)phenylmethyl]...)
Affinity DataKi:  275nMAssay Description:Displacement of [125I]RTI-55 from human DAT receptor expressed in canine kidney cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50254209((2S,3S)-2-[alpha-(2-Methylphenoxy)phenylmethyl]mor...)
Affinity DataKi:  327nMAssay Description:Displacement of [125I]RTI-55 from human DAT receptor expressed in canine kidney cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50254210((2S,3S)-2-[alpha-(2-(2-Fluoroethyl)phenoxy)phenylm...)
Affinity DataKi:  430nMAssay Description:Displacement of [3H]citalopram from human SERT receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50254211((2S,3S)-2-[alpha-(2-(3-Fluoropropyl)phenoxy)phenyl...)
Affinity DataKi:  463nMAssay Description:Displacement of [3H]citalopram from human SERT receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50370475(S,S-REBOXETINE)
Affinity DataKi:  661nMAssay Description:Displacement of [3H]citalopram from human SERT receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50370475(S,S-REBOXETINE)
Affinity DataKi: >2.00E+3nMAssay Description:Displacement of [125I]RTI-55 from human DAT receptor expressed in canine kidney cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50199005((S)-2-((S)-(2-methoxyphenoxy)(phenyl)methyl)morpho...)
Affinity DataKi:  2.00E+3nMAssay Description:Displacement of [125I]RTI-55 from human DAT receptor expressed in canine kidney cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50254211((2S,3S)-2-[alpha-(2-(3-Fluoropropyl)phenoxy)phenyl...)
Affinity DataKi: >6.00E+3nMAssay Description:Displacement of [125I]RTI-55 from human DAT receptor expressed in canine kidney cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50254210((2S,3S)-2-[alpha-(2-(2-Fluoroethyl)phenoxy)phenylm...)
Affinity DataKi: >6.00E+3nMAssay Description:Displacement of [125I]RTI-55 from human DAT receptor expressed in canine kidney cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed