Compile Data Set for Download or QSAR
Report error Found 35 Enz. Inhib. hit(s) with all data for entry = 2983
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Human)
University of Southern California

LigandChemical structure of BindingDB Monomer ID 26602BDBM26602(2-{5-[(3Z)-1-(carboxymethyl)-2-oxo-2,3-dihydro-1H-...)
Affinity DataIC50: 3.00E+3nMAssay Description:To determine the extent of abasic residue cleavage by APE1, recombinant APE1 was preincubated with the potential inhibitors in reaction buffer. Then,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2009
Entry Details Article
PubMed
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Human)
University of Southern California

LigandChemical structure of BindingDB Monomer ID 26576BDBM26576(3-[1-(carboxymethyl)-5-(4-chlorophenyl)-1H-pyrrol-...)
Affinity DataIC50: 4.00E+3nMpH: 7.5 T: 2°CAssay Description:To determine the extent of abasic residue cleavage by APE1, recombinant APE1 was preincubated with the potential inhibitors in reaction buffer. Then,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2009
Entry Details Article
PubMed
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Human)
University of Southern California

LigandChemical structure of BindingDB Monomer ID 26595BDBM26595(2-(2-{4-[1-(carboxymethyl)-1H-1,3-benzodiazol-2-yl...)
Affinity DataIC50: 4.00E+3nMpH: 7.5 T: 2°CAssay Description:To determine the extent of abasic residue cleavage by APE1, recombinant APE1 was preincubated with the potential inhibitors in reaction buffer. Then,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2009
Entry Details Article
PubMed
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Human)
University of Southern California

LigandChemical structure of BindingDB Monomer ID 26580BDBM26580(4-({4-[(4-carboxyphenyl)sulfanyl]benzene}sulfonyl)...)
Affinity DataIC50: 4.00E+3nMpH: 7.5 T: 2°CAssay Description:To determine the extent of abasic residue cleavage by APE1, recombinant APE1 was preincubated with the potential inhibitors in reaction buffer. Then,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2009
Entry Details Article
PubMed
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Human)
University of Southern California

LigandChemical structure of BindingDB Monomer ID 26606BDBM26606(5-{[(2-{[(4-carboxy-5-methylfuran-2-yl)methyl]sulf...)
Affinity DataIC50: 5.00E+3nMAssay Description:To determine the extent of abasic residue cleavage by APE1, recombinant APE1 was preincubated with the potential inhibitors in reaction buffer. Then,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2009
Entry Details Article
PubMed
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Human)
University of Southern California

LigandChemical structure of BindingDB Monomer ID 26604BDBM26604(2-{3-[(5Z)-3-(4-bromophenyl)-4-oxo-2-sulfanylidene...)
Affinity DataIC50: 6.00E+3nMAssay Description:To determine the extent of abasic residue cleavage by APE1, recombinant APE1 was preincubated with the potential inhibitors in reaction buffer. Then,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2009
Entry Details Article
PubMed
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Human)
University of Southern California

LigandChemical structure of BindingDB Monomer ID 26607BDBM26607(5-({[(4-carboxy-5-methylfuran-2-yl)methyl]sulfanyl...)
Affinity DataIC50: 6.00E+3nMAssay Description:To determine the extent of abasic residue cleavage by APE1, recombinant APE1 was preincubated with the potential inhibitors in reaction buffer. Then,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2009
Entry Details Article
PubMed
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Human)
University of Southern California

LigandChemical structure of BindingDB Monomer ID 26592BDBM26592(4-(2-carboxyphenoxymethyl)-2,5-dimethylfuran-3-car...)
Affinity DataIC50: 6.00E+3nMpH: 7.5 T: 2°CAssay Description:To determine the extent of abasic residue cleavage by APE1, recombinant APE1 was preincubated with the potential inhibitors in reaction buffer. Then,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2009
Entry Details Article
PubMed
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Human)
University of Southern California

LigandChemical structure of BindingDB Monomer ID 26593BDBM26593(3-(5-{[(5E)-3-(carboxymethyl)-4-oxo-2-sulfanyliden...)
Affinity DataIC50: 6.00E+3nMpH: 7.5 T: 2°CAssay Description:To determine the extent of abasic residue cleavage by APE1, recombinant APE1 was preincubated with the potential inhibitors in reaction buffer. Then,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2009
Entry Details Article
PubMed
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Human)
University of Southern California

LigandChemical structure of BindingDB Monomer ID 26599BDBM26599(4-({4-[(4-carboxybenzene)sulfonyl]phenyl}sulfanyl)...)
Affinity DataIC50: 6.00E+3nMpH: 7.5 T: 2°CAssay Description:To determine the extent of abasic residue cleavage by APE1, recombinant APE1 was preincubated with the potential inhibitors in reaction buffer. Then,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2009
Entry Details Article
PubMed
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Human)
University of Southern California

LigandChemical structure of BindingDB Monomer ID 26585BDBM26585(3-{5-[(3Z)-1-(carboxymethyl)-2-oxo-2,3-dihydro-1H-...)
Affinity DataIC50: 6.00E+3nMpH: 7.5 T: 2°CAssay Description:To determine the extent of abasic residue cleavage by APE1, recombinant APE1 was preincubated with the potential inhibitors in reaction buffer. Then,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2009
Entry Details Article
PubMed
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Human)
University of Southern California

LigandChemical structure of BindingDB Monomer ID 26587BDBM26587(2-{[3-(1-carboxyethoxy)-9-oxo-8-oxatricyclo[8.4.0....)
Affinity DataIC50: 8.00E+3nMpH: 7.5 T: 2°CAssay Description:To determine the extent of abasic residue cleavage by APE1, recombinant APE1 was preincubated with the potential inhibitors in reaction buffer. Then,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2009
Entry Details Article
PubMed
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Human)
University of Southern California

LigandChemical structure of BindingDB Monomer ID 26594BDBM26594(2-(5-{[2-(2-carboxyphenyl)-1,3-dioxo-2,3-dihydro-1...)
Affinity DataIC50: 8.00E+3nMpH: 7.5 T: 2°CAssay Description:To determine the extent of abasic residue cleavage by APE1, recombinant APE1 was preincubated with the potential inhibitors in reaction buffer. Then,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2009
Entry Details Article
PubMed
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Human)
University of Southern California

LigandChemical structure of BindingDB Monomer ID 26605BDBM26605(2-{2-oxo-3-[(5Z)-4-oxo-2-sulfanylidene-1,3-thiazol...)
Affinity DataIC50: 9.00E+3nMAssay Description:To determine the extent of abasic residue cleavage by APE1, recombinant APE1 was preincubated with the potential inhibitors in reaction buffer. Then,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2009
Entry Details Article
PubMed
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Human)
University of Southern California

LigandChemical structure of BindingDB Monomer ID 26577BDBM26577(3-[1-(carboxymethyl)-5-(thiophen-2-yl)-1H-pyrrol-2...)
Affinity DataIC50: 9.00E+3nMpH: 7.5 T: 2°CAssay Description:To determine the extent of abasic residue cleavage by APE1, recombinant APE1 was preincubated with the potential inhibitors in reaction buffer. Then,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2009
Entry Details Article
PubMed
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Human)
University of Southern California

LigandChemical structure of BindingDB Monomer ID 26598BDBM26598(3-[1-(carboxymethyl)-5-(4-fluorophenyl)-1H-pyrrol-...)
Affinity DataIC50: 9.00E+3nMpH: 7.5 T: 2°CAssay Description:To determine the extent of abasic residue cleavage by APE1, recombinant APE1 was preincubated with the potential inhibitors in reaction buffer. Then,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2009
Entry Details Article
PubMed
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Human)
University of Southern California

LigandChemical structure of BindingDB Monomer ID 26600BDBM26600(4-{[4-(4-carboxyphenoxy)benzene]sulfonyl}benzene-1...)
Affinity DataIC50: 1.00E+4nMpH: 7.5 T: 2°CAssay Description:To determine the extent of abasic residue cleavage by APE1, recombinant APE1 was preincubated with the potential inhibitors in reaction buffer. Then,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2009
Entry Details Article
PubMed
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Human)
University of Southern California

LigandChemical structure of BindingDB Monomer ID 26603BDBM26603(2-{3-[(5Z)-3-[(2-hydroxybenzene)amido]-4-oxo-2-sul...)
Affinity DataIC50: 1.10E+4nMAssay Description:To determine the extent of abasic residue cleavage by APE1, recombinant APE1 was preincubated with the potential inhibitors in reaction buffer. Then,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2009
Entry Details Article
PubMed
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Human)
University of Southern California

LigandChemical structure of BindingDB Monomer ID 26588BDBM26588(2-[10-(carboxymethyl)-6,12-dioxo-5,11-dioxatricycl...)
Affinity DataIC50: 1.10E+4nMpH: 7.5 T: 2°CAssay Description:To determine the extent of abasic residue cleavage by APE1, recombinant APE1 was preincubated with the potential inhibitors in reaction buffer. Then,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2009
Entry Details Article
PubMed
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Human)
University of Southern California

LigandChemical structure of BindingDB Monomer ID 26608BDBM26608(3-(3,4-dimethylphenoxymethyl)furan-2-carboxylic ac...)
Affinity DataIC50: 1.10E+4nMAssay Description:To determine the extent of abasic residue cleavage by APE1, recombinant APE1 was preincubated with the potential inhibitors in reaction buffer. Then,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2009
Entry Details Article
PubMed
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Human)
University of Southern California

LigandChemical structure of BindingDB Monomer ID 26586BDBM26586(4-{5-[(3Z)-1-(carboxymethyl)-2-oxo-2,3-dihydro-1H-...)
Affinity DataIC50: 1.20E+4nMpH: 7.5 T: 2°CAssay Description:To determine the extent of abasic residue cleavage by APE1, recombinant APE1 was preincubated with the potential inhibitors in reaction buffer. Then,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2009
Entry Details Article
PubMed
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Human)
University of Southern California

LigandChemical structure of BindingDB Monomer ID 26597BDBM26597(3-[1-(carboxymethyl)-5-(4-methylphenyl)-1H-pyrrol-...)
Affinity DataIC50: 1.20E+4nMpH: 7.5 T: 2°CAssay Description:To determine the extent of abasic residue cleavage by APE1, recombinant APE1 was preincubated with the potential inhibitors in reaction buffer. Then,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2009
Entry Details Article
PubMed
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Human)
University of Southern California

LigandChemical structure of BindingDB Monomer ID 26601BDBM26601(2-{3-[(5Z)-3-(carboxymethyl)-4-oxo-2-sulfanylidene...)
Affinity DataIC50: 1.30E+4nMAssay Description:To determine the extent of abasic residue cleavage by APE1, recombinant APE1 was preincubated with the potential inhibitors in reaction buffer. Then,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2009
Entry Details Article
PubMed
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Human)
University of Southern California

LigandChemical structure of BindingDB Monomer ID 26579BDBM26579(3-({[4-(carboxymethyl)phenyl]methyl}sulfanyl)-8-me...)
Affinity DataIC50: 1.50E+4nMpH: 7.5 T: 2°CAssay Description:To determine the extent of abasic residue cleavage by APE1, recombinant APE1 was preincubated with the potential inhibitors in reaction buffer. Then,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2009
Entry Details Article
PubMed
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Human)
University of Southern California

LigandChemical structure of BindingDB Monomer ID 26581BDBM26581(3-[3-(2-carboxyethyl)-2-sulfanylidene-2,3-dihydro-...)
Affinity DataIC50: 1.50E+4nMpH: 7.5 T: 2°CAssay Description:To determine the extent of abasic residue cleavage by APE1, recombinant APE1 was preincubated with the potential inhibitors in reaction buffer. Then,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2009
Entry Details Article
PubMed
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Human)
University of Southern California

LigandChemical structure of BindingDB Monomer ID 26610BDBM26610(2-methyl-5-{[(oxolan-2-ylmethyl)sulfanyl]methyl}fu...)
Affinity DataIC50: 1.60E+4nMAssay Description:To determine the extent of abasic residue cleavage by APE1, recombinant APE1 was preincubated with the potential inhibitors in reaction buffer. Then,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2009
Entry Details Article
PubMed
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Human)
University of Southern California

LigandChemical structure of BindingDB Monomer ID 26582BDBM26582(2-[3-(carboxymethyl)-2-oxo-2,3-dihydro-1H-1,3-benz...)
Affinity DataIC50: 1.60E+4nMpH: 7.5 T: 2°CAssay Description:To determine the extent of abasic residue cleavage by APE1, recombinant APE1 was preincubated with the potential inhibitors in reaction buffer. Then,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2009
Entry Details Article
PubMed
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Human)
University of Southern California

LigandChemical structure of BindingDB Monomer ID 26578BDBM26578(3-({5-[(2-carboxyethyl)sulfanyl]-1,3,4-thiadiazol-...)
Affinity DataIC50: 1.70E+4nMpH: 7.5 T: 2°CAssay Description:To determine the extent of abasic residue cleavage by APE1, recombinant APE1 was preincubated with the potential inhibitors in reaction buffer. Then,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2009
Entry Details Article
PubMed
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Human)
University of Southern California

LigandChemical structure of BindingDB Monomer ID 26590BDBM26590(2-({2-[(carboxymethyl)sulfanyl]-6-phenylpyrimidin-...)
Affinity DataIC50: 1.90E+4nMpH: 7.5 T: 2°CAssay Description:To determine the extent of abasic residue cleavage by APE1, recombinant APE1 was preincubated with the potential inhibitors in reaction buffer. Then,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2009
Entry Details Article
PubMed
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Human)
University of Southern California

LigandChemical structure of BindingDB Monomer ID 26589BDBM26589(3-(2-carboxyethyl)-4-hydroxy-2-methylquinoline-6-c...)
Affinity DataIC50: 2.00E+4nMpH: 7.5 T: 2°CAssay Description:To determine the extent of abasic residue cleavage by APE1, recombinant APE1 was preincubated with the potential inhibitors in reaction buffer. Then,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2009
Entry Details Article
PubMed
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Human)
University of Southern California

LigandChemical structure of BindingDB Monomer ID 26596BDBM26596(3-[(6-amino-9H-purin-8-yl)sulfanyl]propanoic acid ...)
Affinity DataIC50: 2.00E+4nMpH: 7.5 T: 2°CAssay Description:To determine the extent of abasic residue cleavage by APE1, recombinant APE1 was preincubated with the potential inhibitors in reaction buffer. Then,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2009
Entry Details Article
PubMed
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Human)
University of Southern California

LigandChemical structure of BindingDB Monomer ID 26584BDBM26584(4-({[(3-carboxy-5-methylfuran-2-yl)methyl]sulfanyl...)
Affinity DataIC50: 2.00E+4nMpH: 7.5 T: 2°CAssay Description:To determine the extent of abasic residue cleavage by APE1, recombinant APE1 was preincubated with the potential inhibitors in reaction buffer. Then,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2009
Entry Details Article
PubMed
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Human)
University of Southern California

LigandChemical structure of BindingDB Monomer ID 26583BDBM26583(4-{[(2-carboxy-2-methylethyl)sulfanyl]methyl}-5-me...)
Affinity DataIC50: 2.20E+4nMpH: 7.5 T: 2°CAssay Description:To determine the extent of abasic residue cleavage by APE1, recombinant APE1 was preincubated with the potential inhibitors in reaction buffer. Then,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2009
Entry Details Article
PubMed
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Human)
University of Southern California

LigandChemical structure of BindingDB Monomer ID 26591BDBM26591(2-({4-[(carboxymethyl)carbamoyl]-2,5-dimethylfuran...)
Affinity DataIC50: 2.60E+4nMpH: 7.5 T: 2°CAssay Description:To determine the extent of abasic residue cleavage by APE1, recombinant APE1 was preincubated with the potential inhibitors in reaction buffer. Then,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2009
Entry Details Article
PubMed
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Human)
University of Southern California

LigandChemical structure of BindingDB Monomer ID 26609BDBM26609(3-[(pyridin-2-ylsulfanyl)methyl]-1-benzofuran-2-ca...)
Affinity DataIC50: 2.70E+4nMAssay Description:To determine the extent of abasic residue cleavage by APE1, recombinant APE1 was preincubated with the potential inhibitors in reaction buffer. Then,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2009
Entry Details Article
PubMed