Compile Data Set for Download or QSAR
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Report error Found 224 Enz. Inhib. hit(s) with all data for entry = 50027873
TargetAdenosine receptor A2a(Human)
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254012(3-(4-Amino-3-fluorobenzyl)-7-(2-furyl)-3H-[1,2,3]t...)
Affinity DataKi:  0.700nMAssay Description:Displacement of radioligand from human recombinant adenosine A2A receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A2a(Human)
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254353(3-(4-Amino-3-ethylbenzyl)-7-(2-furyl)-3H-[1,2,3]tr...)
Affinity DataKi:  1nMAssay Description:Displacement of radioligand from human recombinant adenosine A2A receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A2a(Human)
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254398(7-(2-Furyl)-3-(5-indolylmethyl)-3H-[1,2,3]triazolo...)
Affinity DataKi:  1.10nMAssay Description:Displacement of radioligand from human recombinant adenosine A2A receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A2a(Human)
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254013(3-(4-Amino-3-methylbenzyl)-7-(2-furyl)-3H-[1,2,3]t...)
Affinity DataKi:  1.30nMAssay Description:Displacement of radioligand from human recombinant adenosine A2A receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetAdenosine receptor A2a(Human)
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254009(3-(4-Aminobenzyl)-7-(2-furyl)-3H-[1,2,3]triazolo[4...)
Affinity DataKi:  1.5nMAssay Description:Displacement of radioligand from human recombinant adenosine A2A receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A2a(Human)
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254354(3-(4-Amino-3-isopropylbenzyl)-7-(2-furyl)-3H-[1,2,...)
Affinity DataKi:  1.5nMAssay Description:Displacement of radioligand from human recombinant adenosine A2A receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A2a(Human)
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254356(7-(2-Furyl)-3-(4-(N-methylamino)benzyl)-3H-[1,2,3]...)
Affinity DataKi:  1.60nMAssay Description:Displacement of radioligand from human recombinant adenosine A2A receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A2a(Human)
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254355(3-(4-Amino-3-hydroxybenzyl)-7-(2-furyl)-3H-[1,2,3]...)
Affinity DataKi:  1.60nMAssay Description:Displacement of radioligand from human recombinant adenosine A2A receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A2a(Human)
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254004(7-(2-Furyl)-3-(3-methoxybenzyl)-3H-[1,2,3]triazolo...)
Affinity DataKi:  1.80nMAssay Description:Displacement of radioligand from human recombinant adenosine A2A receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A2a(Human)
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254300(3-(2,6-Difluorobenzyl)-7-(2-furyl)-3H-[1,2,3]triaz...)
Affinity DataKi:  1.90nMAssay Description:Displacement of radioligand from human recombinant adenosine A2A receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A2a(Human)
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50253994(7-(2-Furyl)-3-(3-thienylmethyl)-3H-[1,2,3]triazolo...)
Affinity DataKi:  1.90nMAssay Description:Displacement of radioligand from human recombinant adenosine A2A receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A2a(Human)
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254295(3-Benzyl-7-(2-furyl)-3H-[1,2,3]triazolo[4,5-d]pyri...)
Affinity DataKi:  1.90nMAssay Description:Displacement of radioligand from human recombinant adenosine A2A receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A2a(Human)
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254298(3-(2,4-Difluorobenzyl)-7-(2-furyl)-3H-[1,2,3]triaz...)
Affinity DataKi:  2nMAssay Description:Displacement of radioligand from human recombinant adenosine A2A receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A2a(Human)
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50253995(3-(2-Aminobenzyl)-7-(2-furyl)-3H-[1,2,3]triazolo[4...)
Affinity DataKi:  2nMAssay Description:Displacement of radioligand from human recombinant adenosine A2A receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A2a(Human)
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254000(3-(2-Fluorobenzyl)-7-(5-methyl-2-furyl)-3H-[1,2,3]...)
Affinity DataKi:  2.10nMAssay Description:Displacement of radioligand from human recombinant adenosine A2A receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A2a(Human)
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50253990(7-(2-Furyl)-3-(3-trifluoromethylbenzyl)-3H-[1,2,3]...)
Affinity DataKi:  2.20nMAssay Description:Displacement of radioligand from human recombinant adenosine A2A receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A2a(Human)
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254262(3-(2-Fluorobenzyl)-7-(4-methyl-2-thiazolyl)-3H-[1,...)
Affinity DataKi:  2.20nMAssay Description:Displacement of radioligand from human recombinant adenosine A2A receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A2a(Human)
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254299(3-(2,5-Difluorobenzyl)-7-(2-furyl)-3H-[1,2,3]triaz...)
Affinity DataKi:  2.20nMAssay Description:Displacement of radioligand from human recombinant adenosine A2A receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A2a(Human)
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50253993(7-(2-Furyl)-3-(2-thienylmethyl)-3H-[1,2,3]triazolo...)
Affinity DataKi:  2.30nMAssay Description:Displacement of radioligand from human recombinant adenosine A2A receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A2a(Human)
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254297(3-(2,3-Difluorobenzyl)-7-(2-furyl)-3H-[1,2,3]triaz...)
Affinity DataKi:  2.30nMAssay Description:Displacement of radioligand from human recombinant adenosine A2A receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A2a(Human)
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50253987(3-(3-Chlorobenzyl)-7-(2-furyl)-3H-[1,2,3]triazolo[...)
Affinity DataKi:  2.30nMAssay Description:Displacement of radioligand from human recombinant adenosine A2A receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A2a(Human)
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254008(3-(3-Aminobenzyl)-7-(2-furyl)-3H-[1,2,3]triazolo[4...)
Affinity DataKi:  2.5nMAssay Description:Displacement of radioligand from human recombinant adenosine A2A receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A2a(Human)
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50253999(3-(2-Fluorobenzyl)-7-(2-furyl)-3H-[1,2,3]triazolo[...)
Affinity DataKi:  2.70nMAssay Description:Displacement of radioligand from human recombinant adenosine A2A receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A2a(Human)
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50253989(7-(2-Furyl)-3-(3-methylbenzyl)-3H-[1,2,3]triazolo[...)
Affinity DataKi:  3nMAssay Description:Displacement of radioligand from human recombinant adenosine A2A receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A2a(Human)
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50253988(7-(2-Furyl)-3-(2-methylbenzyl)-3H-[1,2,3]triazolo[...)
Affinity DataKi:  3nMAssay Description:Displacement of radioligand from human recombinant adenosine A2A receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A2a(Human)
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254011(3-(4-Amino-2-fluorobenzyl)-7-(2-furyl)-3H-[1,2,3]t...)
Affinity DataKi:  3.5nMAssay Description:Displacement of radioligand from human recombinant adenosine A2A receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A2a(Human)
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254301(7-(2-Furyl)-3-(3-nitrobenzyl)-3H-[1,2,3]triazolo[4...)
Affinity DataKi:  3.70nMAssay Description:Displacement of radioligand from human recombinant adenosine A2A receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A2a(Human)
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254005(3-(3-Cyanobenzyl)-7-(2-furyl)-3H-[1,2,3]triazolo[4...)
Affinity DataKi:  3.90nMAssay Description:Displacement of radioligand from human recombinant adenosine A2A receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A2a(Human)
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254304(7-(2-Furyl)-3-(3-hydroxybenzyl)-3H-[1,2,3]triazolo...)
Affinity DataKi:  4nMAssay Description:Displacement of radioligand from human recombinant adenosine A2A receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A2a(Human)
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254303(CHEMBL517429 | Methyl 3-(5-Amino-7-(2-furyl)-3H-[1...)
Affinity DataKi:  4.10nMAssay Description:Displacement of radioligand from human recombinant adenosine A2A receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A2a(Human)
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254003(7-(2-Furyl)-3-(2-methoxybenzyl)-3H-[1,2,3]triazolo...)
Affinity DataKi:  5.40nMAssay Description:Displacement of radioligand from human recombinant adenosine A2A receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A2b(Human)
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254000(3-(2-Fluorobenzyl)-7-(5-methyl-2-furyl)-3H-[1,2,3]...)
Affinity DataKi:  6nMAssay Description:Displacement of radioligand from human recombinant adenosine A2B receptor at 21 degC after 60 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A2a(Human)
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254007(7-(2-Furyl)-3-(2-nitrobenzyl)-3H-[1,2,3]triazolo[4...)
Affinity DataKi:  6.60nMAssay Description:Displacement of radioligand from human recombinant adenosine A2A receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A2a(Human)
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254265(3-(2-Fluorobenzyl)-7-(2-thienyl)-3H-[1,2,3]triazol...)
Affinity DataKi:  8.20nMAssay Description:Displacement of radioligand from human recombinant adenosine A2A receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A2a(Human)
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254263(3-(2-Fluorobenzyl)-7-(5-methyl-2-thiazolyl)-3H-[1,...)
Affinity DataKi:  8.5nMAssay Description:Displacement of radioligand from human recombinant adenosine A2A receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A2a(Human)
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254002(3-(2-Fluorobenzyl)-7-(2-thiazolyl)-3H-[1,2,3]triaz...)
Affinity DataKi:  8.5nMAssay Description:Displacement of radioligand from human recombinant adenosine A2A receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A2a(Human)
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254296(3-Cyclohexylmethyl-7-(2-furyl)-3H-[1,2,3]triazolo[...)
Affinity DataKi:  8.5nMAssay Description:Displacement of radioligand from human recombinant adenosine A2A receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A2a(Human)
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254399(7-(2-Furyl)-3-(5-indazolylmethyl)-3H-[1,2,3]triazo...)
Affinity DataKi:  8.60nMAssay Description:Displacement of radioligand from human recombinant adenosine A2A receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A2a(Human)
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50253992(7-(2-Furyl)-3-(2-furylmethyl)-3H-[1,2,3]triazolo[4...)
Affinity DataKi:  8.80nMAssay Description:Displacement of radioligand from human recombinant adenosine A2A receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A2b(Human)
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254304(7-(2-Furyl)-3-(3-hydroxybenzyl)-3H-[1,2,3]triazolo...)
Affinity DataKi:  10nMAssay Description:Displacement of radioligand from human recombinant adenosine A2B receptor at 21 degC after 60 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A2a(Human)
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254349(3-(5-Amino-7-(2-furyl)-3H-[1,2,3]triazolo[4,5-d]py...)
Affinity DataKi:  10.8nMAssay Description:Displacement of radioligand from human recombinant adenosine A2A receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A2a(Human)
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254348(3-(5-Amino-7-(2-furyl)-3H-[1,2,3]triazolo[4,5-d]py...)
Affinity DataKi:  11.1nMAssay Description:Displacement of radioligand from human recombinant adenosine A2A receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A2a(Human)
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254400(3-(1H-Benzotriazol-5-ylmethyl)-7-(2-furyl)-3H-[1,2...)
Affinity DataKi:  11.9nMAssay Description:Displacement of radioligand from human recombinant adenosine A2A receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A2a(Human)
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254351(7-(2-Furyl)-3-(2-pyridylmethyl)-3H-[1,2,3]triazolo...)
Affinity DataKi:  12nMAssay Description:Displacement of radioligand from human recombinant adenosine A2A receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A2a(Human)
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254352(7-(2-Furyl)-3-(3-pyridylmethyl)-3H-[1,2,3]triazolo...)
Affinity DataKi:  14.5nMAssay Description:Displacement of radioligand from human recombinant adenosine A2A receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A1(Human)
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254000(3-(2-Fluorobenzyl)-7-(5-methyl-2-furyl)-3H-[1,2,3]...)
Affinity DataKi:  19nMAssay Description:Displacement of radioligand from human recombinant adenosine A1 receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A2a(Human)
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254350(3-(5-Amino-7-(2-furyl)-3H-[1,2,3]triazolo[4,5-d]py...)
Affinity DataKi:  22nMAssay Description:Displacement of radioligand from human recombinant adenosine A2A receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A2b(Human)
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254011(3-(4-Amino-2-fluorobenzyl)-7-(2-furyl)-3H-[1,2,3]t...)
Affinity DataKi:  23nMAssay Description:Displacement of radioligand from human recombinant adenosine A2B receptor at 21 degC after 60 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A2b(Human)
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254300(3-(2,6-Difluorobenzyl)-7-(2-furyl)-3H-[1,2,3]triaz...)
Affinity DataKi:  24nMAssay Description:Displacement of radioligand from human recombinant adenosine A2B receptor at 21 degC after 60 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A1(Human)
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254353(3-(4-Amino-3-ethylbenzyl)-7-(2-furyl)-3H-[1,2,3]tr...)
Affinity DataKi:  26nMAssay Description:Displacement of radioligand from human recombinant adenosine A1 receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

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