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Found 8 Enz. Inhib. hit(s) with all data for entry = 5670
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Yang-Ming University

LigandPNGBDBM92520(TG-0204998)
Affinity DataKi:  38nM ΔG°:  -42.4kJ/molepH: 6.5 T: 2°CAssay Description:Peptidomimetic inhibitors against CVB3 3Cpro and SARS-CoV 3CLpro. The inhibition constant of SARS 3CLpro was analyzed with reverse-phase HPLC using a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Yang-Ming University

LigandPNGBDBM11233(N-[(benzyloxy)carbonyl]-O-(tert-butyl)-L-threonyl-...)
Affinity DataKi:  54nM ΔG°:  -41.5kJ/molepH: 6.5 T: 2°CAssay Description:Peptidomimetic inhibitors against CVB3 3Cpro and SARS-CoV 3CLpro. The inhibition constant of SARS 3CLpro was analyzed with reverse-phase HPLC using a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Yang-Ming University

LigandPNGBDBM11232(N-[(benzyloxy)carbonyl]-O-(tert-butyl)-L-threonyl-...)
Affinity DataKi:  58nM ΔG°:  -41.3kJ/molepH: 6.5 T: 2°CAssay Description:Peptidomimetic inhibitors against CVB3 3Cpro and SARS-CoV 3CLpro. The inhibition constant of SARS 3CLpro was analyzed with reverse-phase HPLC using a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Yang-Ming University

LigandPNGBDBM92521(TG-0205486)
Affinity DataKi:  99nM ΔG°:  -40.0kJ/molepH: 6.5 T: 2°CAssay Description:Peptidomimetic inhibitors against CVB3 3Cpro and SARS-CoV 3CLpro. The inhibition constant of SARS 3CLpro was analyzed with reverse-phase HPLC using a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Coxsackievirus B3 (strain Nancy))
National Yang-Ming University

LigandPNGBDBM92521(TG-0205486)
Affinity DataKi:  400nM ΔG°:  -36.5kJ/molepH: 6.5 T: 2°CAssay Description:Peptidomimetic inhibitors against CVB3 3Cpro and SARS-CoV 3CLpro. The inhibition constant of SARS 3CLpro was analyzed with reverse-phase HPLC using a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Coxsackievirus B3 (strain Nancy))
National Yang-Ming University

LigandPNGBDBM92520(TG-0204998)
Affinity DataKi:  800nM ΔG°:  -34.8kJ/molepH: 6.5 T: 2°CAssay Description:Peptidomimetic inhibitors against CVB3 3Cpro and SARS-CoV 3CLpro. The inhibition constant of SARS 3CLpro was analyzed with reverse-phase HPLC using a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Coxsackievirus B3 (strain Nancy))
National Yang-Ming University

LigandPNGBDBM11232(N-[(benzyloxy)carbonyl]-O-(tert-butyl)-L-threonyl-...)
Affinity DataKi:  1.50E+3nM ΔG°:  -33.2kJ/molepH: 6.5 T: 2°CAssay Description:Peptidomimetic inhibitors against CVB3 3Cpro and SARS-CoV 3CLpro. The inhibition constant of SARS 3CLpro was analyzed with reverse-phase HPLC using a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Coxsackievirus B3 (strain Nancy))
National Yang-Ming University

LigandPNGBDBM11233(N-[(benzyloxy)carbonyl]-O-(tert-butyl)-L-threonyl-...)
Affinity DataKi:  2.50E+3nM ΔG°:  -32.0kJ/molepH: 6.5 T: 2°CAssay Description:Peptidomimetic inhibitors against CVB3 3Cpro and SARS-CoV 3CLpro. The inhibition constant of SARS 3CLpro was analyzed with reverse-phase HPLC using a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed