Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 3080
TargetGag-Pol polyprotein [1148-1435](Human immunodeficiency virus type 1)
Gilead Sciences

LigandPNGBDBM27749(3-[(4-fluorophenyl)methyl]-9-hydroxy-5-methoxy-6H,...)
Affinity DataIC50: 14nMpH: 7.3 T: 2°CAssay Description:In the strand-transfer assay, the biotinylated donor DNA was bound to streptavidin-coated plates, and integrase was added to each well to allow proce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [1148-1435](Human immunodeficiency virus type 1)
Gilead Sciences

LigandPNGBDBM27751(N-{3-[(4-fluorophenyl)methyl]-9-hydroxy-7-methyl-8...)
Affinity DataIC50: 80nMpH: 7.3 T: 2°CAssay Description:In the strand-transfer assay, the biotinylated donor DNA was bound to streptavidin-coated plates, and integrase was added to each well to allow proce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [1148-1435](Human immunodeficiency virus type 1)
Gilead Sciences

LigandPNGBDBM27748(3-[(4-fluorophenyl)methyl]-9-hydroxy-5-methoxy-7-m...)
Affinity DataIC50: 100nMpH: 7.3 T: 2°CAssay Description:In the strand-transfer assay, the biotinylated donor DNA was bound to streptavidin-coated plates, and integrase was added to each well to allow proce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [1148-1435](Human immunodeficiency virus type 1)
Gilead Sciences

LigandPNGBDBM27752(N-{3-[(3-chloro-4-fluorophenyl)methyl]-9-hydroxy-7...)
Affinity DataIC50: 265nMpH: 7.3 T: 2°CAssay Description:In the strand-transfer assay, the biotinylated donor DNA was bound to streptavidin-coated plates, and integrase was added to each well to allow proce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [1148-1435](Human immunodeficiency virus type 1)
Gilead Sciences

LigandPNGBDBM27750(3,7-bis[(4-fluorophenyl)methyl]-9-hydroxy-5-methox...)
Affinity DataIC50: 600nMpH: 7.3 T: 2°CAssay Description:In the strand-transfer assay, the biotinylated donor DNA was bound to streptavidin-coated plates, and integrase was added to each well to allow proce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2009
Entry Details Article
PubMed