Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50028153
TargetC-C chemokine receptor type 5(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50276291(N-benzyl-N-(1'-(2,6-dimethylbenzoyl)-4'-methyl-1,4...)
Affinity DataIC50: 0.5nMAssay Description:Antagonist activity at human recombinant CCR5 expressed in human HeLa-P4 cells assessed as inhibition of human HeLa-P4 cells binding to HIV1 gp160 ex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50276260((R)-N-benzyl-N-(1-(1-(2,6-dimethylbenzoyl)piperidi...)
Affinity DataIC50: 1nMAssay Description:Antagonist activity at human recombinant CCR5 expressed in human HeLa-P4 cells assessed as inhibition of human HeLa-P4 cells binding to HIV1 gp160 ex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50276259(exo-N-benzyl-N-((R)-1-(8-(2,6-dimethylbenzoyl)-8-a...)
Affinity DataIC50: 1nMAssay Description:Antagonist activity at human recombinant CCR5 expressed in human HeLa-P4 cells assessed as inhibition of human HeLa-P4 cells binding to HIV1 gp160 ex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50276290(N-benzyl-N-(1'-(2,6-dimethylbenzoyl)-1,4'-bipiperi...)
Affinity DataIC50: 3nMAssay Description:Antagonist activity at human recombinant CCR5 expressed in human HeLa-P4 cells assessed as inhibition of human HeLa-P4 cells binding to HIV1 gp160 ex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50276260((R)-N-benzyl-N-(1-(1-(2,6-dimethylbenzoyl)piperidi...)
Affinity DataIC50: 8nMAssay Description:Displacement of [125]Mip1beta form CCR5 receptor expressed in MIP34.10 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50276623((4-((1-benzhydrylazetidin-3-yl)(methyl)amino)piper...)
Affinity DataIC50: 24nMAssay Description:Antagonist activity at human recombinant CCR5 expressed in human HeLa-P4 cells assessed as inhibition of human HeLa-P4 cells binding to HIV1 gp160 ex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50276672((4-(3-benzhydryl-3,8-diazabicyclo[3.2.1]octan-8-yl...)
Affinity DataIC50: 41nMAssay Description:Antagonist activity at human recombinant CCR5 expressed in human HeLa-P4 cells assessed as inhibition of human HeLa-P4 cells binding to HIV1 gp160 ex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50276793(rac-N-(2-(3-(2,2-diphenylethyl)piperidin-1-yl)ethy...)
Affinity DataIC50: 56nMAssay Description:Antagonist activity at human recombinant CCR5 expressed in human HeLa-P4 cells assessed as inhibition of human HeLa-P4 cells binding to HIV1 gp160 ex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50276792((3-((1-benzhydrylpiperidin-4-yl)(methyl)amino)azet...)
Affinity DataIC50: 102nMAssay Description:Antagonist activity at human recombinant CCR5 expressed in human HeLa-P4 cells assessed as inhibition of human HeLa-P4 cells binding to HIV1 gp160 ex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50276217(N-((4-benzyl-1'-(2,6-dimethylbenzoyl)-1,4'-bipiper...)
Affinity DataIC50: 145nMAssay Description:Antagonist activity at human recombinant CCR5 expressed in human HeLa-P4 cells assessed as inhibition of human HeLa-P4 cells binding to HIV1 gp160 ex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50276671((4-(8-benzhydryl-3,8-diazabicyclo[3.2.1]octan-3-yl...)
Affinity DataIC50: 313nMAssay Description:Antagonist activity at human recombinant CCR5 expressed in human HeLa-P4 cells assessed as inhibition of human HeLa-P4 cells binding to HIV1 gp160 ex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50276261((S)-N-benzyl-N-(1-(1-(2,6-dimethylbenzoyl)piperidi...)
Affinity DataIC50: 1.23E+3nMAssay Description:Antagonist activity at human recombinant CCR5 expressed in human HeLa-P4 cells assessed as inhibition of human HeLa-P4 cells binding to HIV1 gp160 ex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50276078(N-((1-(1-(2,6-dimethylbenzoyl)piperidin-4-yl)azeti...)
Affinity DataIC50: 2.49E+3nMAssay Description:Antagonist activity at human recombinant CCR5 expressed in human HeLa-P4 cells assessed as inhibition of human HeLa-P4 cells binding to HIV1 gp160 ex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50276290(N-benzyl-N-(1'-(2,6-dimethylbenzoyl)-1,4'-bipiperi...)
Affinity DataIC50: 3.41E+3nMAssay Description:Displacement of [3H]dofetilide form human ERG expressed in HEK239 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50276292(N-benzyl-N-(1-(1-(2,6-dimethylbenzoyl)piperidin-4-...)
Affinity DataIC50: 5.80E+3nMAssay Description:Antagonist activity at human recombinant CCR5 expressed in human HeLa-P4 cells assessed as inhibition of human HeLa-P4 cells binding to HIV1 gp160 ex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50276260((R)-N-benzyl-N-(1-(1-(2,6-dimethylbenzoyl)piperidi...)
Affinity DataIC50: 9.80E+3nMAssay Description:Displacement of [3H]dofetilide form human ERG expressed in HEK239 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed