Compile Data Set for Download or QSAR
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Report error Found 58 Enz. Inhib. hit(s) with all data for entry = 50028159
TargetMu-type opioid receptor(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50276409((1S,2S)-N-(2-methoxyethyl)-2-(thiophen-3-yl)-1,2,3...)
Affinity DataIC50:  5.30nMAssay Description:Displacement of [125I]FK33824 from human cloned mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50276496(3-chloro-N-(2-methoxyethyl)-N-((1R,2R)-2-(4-phenyl...)
Affinity DataIC50:  58nMAssay Description:Displacement of [125I]FK33824 from human cloned mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50276363((+/-)-N-(2-methoxyethyl)-2-(thiophen-3-yl)-1,2,3,4...)
Affinity DataIC50:  69nMAssay Description:Displacement of [125I]FK33824 from human cloned mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50276495((+/-)-3-chloro-N-(2-methoxyethyl)-N-(2-(4-phenylpi...)
Affinity DataIC50:  100nMAssay Description:Displacement of [125I]FK33824 from human cloned mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50276411((+/-)-N-(2-methoxyethyl)-N-(2-(4-phenylpiperazin-1...)
Affinity DataIC50:  126nMAssay Description:Displacement of [125I]FK33824 from human cloned mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50276445((+/-)-N-(2-methoxyethyl)-2-(3-methoxyphenyl)-N-(2-...)
Affinity DataIC50:  151nMAssay Description:Displacement of [125I]FK33824 from human cloned mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetKappa-type opioid receptor(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50276497((+/-)-2-(4-chlorophenoxy)-N-(2-(dimethylamino)-6,7...)
Affinity DataIC50:  155nMAssay Description:Displacement of [125I]U69593 from human cloned kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50276446((+/-)-2-(4-chlorophenyl)-N-(2-methoxyethyl)-N-(2-(...)
Affinity DataIC50:  181nMAssay Description:Displacement of [125I]FK33824 from human cloned mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50276444((+/-)-2-(benzyloxy)-N-(2-methoxyethyl)-N-(2-(4-phe...)
Affinity DataIC50:  211nMAssay Description:Displacement of [125I]FK33824 from human cloned mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50276497((+/-)-2-(4-chlorophenoxy)-N-(2-(dimethylamino)-6,7...)
Affinity DataIC50:  245nMAssay Description:Displacement of [125I]FK33824 from human cloned mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50276498((+/-)-3,4-dichloro-N-(2-(dimethylamino)-6,7-dimeth...)
Affinity DataIC50:  351nMAssay Description:Displacement of [125I]FK33824 from human cloned mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50276412((+/-)-3,4-dichloro-N-(2-methoxyethyl)-N-(2-(4-phen...)
Affinity DataIC50:  443nMAssay Description:Displacement of [125I]FK33824 from human cloned mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetKappa-type opioid receptor(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50276409((1S,2S)-N-(2-methoxyethyl)-2-(thiophen-3-yl)-1,2,3...)
Affinity DataIC50:  707nMAssay Description:Displacement of [125I]U69593 from human cloned kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50276624((1R,2R)-N-(2-methoxyethyl)-2-(thiophen-3-yl)-1,2,3...)
Affinity DataIC50:  772nMAssay Description:Displacement of [125I]FK33824 from human cloned mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetKappa-type opioid receptor(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50276566((+/-)-2-(4-chlorophenyl)-N-(2-(dimethylamino)-6,7-...)
Affinity DataIC50:  922nMAssay Description:Displacement of [125I]U69593 from human cloned kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetKappa-type opioid receptor(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50276567((+/-)-2-(2-bromophenyl)-N-(2-(dimethylamino)-6,7-d...)
Affinity DataIC50:  1.01E+3nMAssay Description:Displacement of [125I]U69593 from human cloned kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50276566((+/-)-2-(4-chlorophenyl)-N-(2-(dimethylamino)-6,7-...)
Affinity DataIC50:  1.12E+3nMAssay Description:Displacement of [125I]FK33824 from human cloned mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDelta-type opioid receptor(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50276496(3-chloro-N-(2-methoxyethyl)-N-((1R,2R)-2-(4-phenyl...)
Affinity DataIC50:  1.24E+3nMAssay Description:Displacement of [125I]deltorphin 2 from human cloned delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDelta-type opioid receptor(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50276410((+/-)-N-(2-methoxyethyl)-2-(thiophen-3-yl)-1,2,3,4...)
Affinity DataIC50:  1.27E+3nMAssay Description:Displacement of [125I]deltorphin 2 from human cloned delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetKappa-type opioid receptor(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50276496(3-chloro-N-(2-methoxyethyl)-N-((1R,2R)-2-(4-phenyl...)
Affinity DataIC50:  1.32E+3nMAssay Description:Displacement of [125I]U69593 from human cloned kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDelta-type opioid receptor(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50276445((+/-)-N-(2-methoxyethyl)-2-(3-methoxyphenyl)-N-(2-...)
Affinity DataIC50:  1.47E+3nMAssay Description:Displacement of [125I]deltorphin 2 from human cloned delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDelta-type opioid receptor(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50276446((+/-)-2-(4-chlorophenyl)-N-(2-methoxyethyl)-N-(2-(...)
Affinity DataIC50:  1.96E+3nMAssay Description:Displacement of [125I]deltorphin 2 from human cloned delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetKappa-type opioid receptor(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50276363((+/-)-N-(2-methoxyethyl)-2-(thiophen-3-yl)-1,2,3,4...)
Affinity DataIC50:  2.21E+3nMAssay Description:Displacement of [125I]U69593 from human cloned kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDelta-type opioid receptor(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50276495((+/-)-3-chloro-N-(2-methoxyethyl)-N-(2-(4-phenylpi...)
Affinity DataIC50:  2.29E+3nMAssay Description:Displacement of [125I]deltorphin 2 from human cloned delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50276569(3-chloro-N-(2-methoxyethyl)-N-((1S,2S)-2-(4-phenyl...)
Affinity DataIC50:  2.80E+3nMAssay Description:Displacement of [125I]FK33824 from human cloned mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDelta-type opioid receptor(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50276498((+/-)-3,4-dichloro-N-(2-(dimethylamino)-6,7-dimeth...)
Affinity DataIC50:  3.50E+3nMAssay Description:Displacement of [125I]deltorphin 2 from human cloned delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDelta-type opioid receptor(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50276412((+/-)-3,4-dichloro-N-(2-methoxyethyl)-N-(2-(4-phen...)
Affinity DataIC50:  3.62E+3nMAssay Description:Displacement of [125I]deltorphin 2 from human cloned delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDelta-type opioid receptor(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50276409((1S,2S)-N-(2-methoxyethyl)-2-(thiophen-3-yl)-1,2,3...)
Affinity DataIC50:  3.80E+3nMAssay Description:Displacement of [125I]deltorphin 2 from human cloned delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDelta-type opioid receptor(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50276444((+/-)-2-(benzyloxy)-N-(2-methoxyethyl)-N-(2-(4-phe...)
Affinity DataIC50:  3.89E+3nMAssay Description:Displacement of [125I]deltorphin 2 from human cloned delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDelta-type opioid receptor(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50276411((+/-)-N-(2-methoxyethyl)-N-(2-(4-phenylpiperazin-1...)
Affinity DataIC50:  3.95E+3nMAssay Description:Displacement of [125I]deltorphin 2 from human cloned delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50276567((+/-)-2-(2-bromophenyl)-N-(2-(dimethylamino)-6,7-d...)
Affinity DataIC50:  4.83E+3nMAssay Description:Displacement of [125I]FK33824 from human cloned mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50276410((+/-)-N-(2-methoxyethyl)-2-(thiophen-3-yl)-1,2,3,4...)
Affinity DataIC50:  4.86E+3nMAssay Description:Displacement of [125I]FK33824 from human cloned mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetKappa-type opioid receptor(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50276498((+/-)-3,4-dichloro-N-(2-(dimethylamino)-6,7-dimeth...)
Affinity DataIC50:  6.00E+3nMAssay Description:Displacement of [125I]U69593 from human cloned kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetKappa-type opioid receptor(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50276495((+/-)-3-chloro-N-(2-methoxyethyl)-N-(2-(4-phenylpi...)
Affinity DataIC50:  7.14E+3nMAssay Description:Displacement of [125I]U69593 from human cloned kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDelta-type opioid receptor(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50276363((+/-)-N-(2-methoxyethyl)-2-(thiophen-3-yl)-1,2,3,4...)
Affinity DataIC50:  7.16E+3nMAssay Description:Displacement of [125I]deltorphin 2 from human cloned delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetKappa-type opioid receptor(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50276446((+/-)-2-(4-chlorophenyl)-N-(2-methoxyethyl)-N-(2-(...)
Affinity DataIC50:  7.99E+3nMAssay Description:Displacement of [125I]U69593 from human cloned kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDelta-type opioid receptor(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50276566((+/-)-2-(4-chlorophenyl)-N-(2-(dimethylamino)-6,7-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]deltorphin 2 from human cloned delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDelta-type opioid receptor(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50276497((+/-)-2-(4-chlorophenoxy)-N-(2-(dimethylamino)-6,7...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]deltorphin 2 from human cloned delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetKappa-type opioid receptor(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50276410((+/-)-N-(2-methoxyethyl)-2-(thiophen-3-yl)-1,2,3,4...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]U69593 from human cloned kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetKappa-type opioid receptor(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50276411((+/-)-N-(2-methoxyethyl)-N-(2-(4-phenylpiperazin-1...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]U69593 from human cloned kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetKappa-type opioid receptor(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50276412((+/-)-3,4-dichloro-N-(2-methoxyethyl)-N-(2-(4-phen...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]U69593 from human cloned kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetKappa-type opioid receptor(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50276444((+/-)-2-(benzyloxy)-N-(2-methoxyethyl)-N-(2-(4-phe...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]U69593 from human cloned kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetKappa-type opioid receptor(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50276445((+/-)-N-(2-methoxyethyl)-2-(3-methoxyphenyl)-N-(2-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]U69593 from human cloned kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDelta-type opioid receptor(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50276567((+/-)-2-(2-bromophenyl)-N-(2-(dimethylamino)-6,7-d...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]deltorphin 2 from human cloned delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50276409((1S,2S)-N-(2-methoxyethyl)-2-(thiophen-3-yl)-1,2,3...)
Affinity DataIC50:  1.90E+4nMAssay Description:Activity at human cloned mu opioid receptor assessed as reversal of DAMGO-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50276446((+/-)-2-(4-chlorophenyl)-N-(2-methoxyethyl)-N-(2-(...)
Affinity DataEC50: >9.00E+4nMAssay Description:Agonist activity at human cloned mu opioid receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50276568(CHEMBL1685 | DEZOCINE | Dalgan | US10231963, Table...)
Affinity DataEC50:  38nMAssay Description:Activity at human cloned mu opioid receptor assessed as reversal of DAMGO-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank


TargetMu-type opioid receptor(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50026752(1-Methyl-4-phenyl-piperidine-4-carboxylic acid eth...)
Affinity DataEC50:  9.40E+3nMAssay Description:Activity at human cloned mu opioid receptor assessed as reversal of DAMGO-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank


TargetMu-type opioid receptor(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50276498((+/-)-3,4-dichloro-N-(2-(dimethylamino)-6,7-dimeth...)
Affinity DataEC50: >9.00E+4nMAssay Description:Activity at human cloned mu opioid receptor assessed as reversal of DAMGO-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50276412((+/-)-3,4-dichloro-N-(2-methoxyethyl)-N-(2-(4-phen...)
Affinity DataEC50: >9.00E+4nMAssay Description:Activity at human cloned mu opioid receptor assessed as reversal of DAMGO-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

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