Compile Data Set for Download or QSAR
Report error Found 38 Enz. Inhib. hit(s) with all data for entry = 50028228
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50248503BDBM50248503(N-(diaminomethylene)-2-(2,5-dichlorophenyl)-5-meth...)
Affinity DataIC50: 72nMAssay Description:Inhibition of human NHE1 expressed in PS120 cells assessed as imposed acidosisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50248341BDBM50248341(N-(diaminomethylene)-2-(2,5-dichlorophenyl)-5-meth...)
Affinity DataIC50: 100nMAssay Description:Inhibition of human NHE1 expressed in PS120 cells assessed as imposed acidosisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50248408BDBM50248408(N-(diaminomethylene)-2-(2,5-dimethylphenyl)-5-meth...)
Affinity DataIC50: 220nMAssay Description:Inhibition of human NHE1 expressed in PS120 cells assessed as imposed acidosisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50248404BDBM50248404(2-(5-chloro-2-methoxyphenyl)-N-(diaminomethylene)-...)
Affinity DataIC50: 240nMAssay Description:Inhibition of human NHE1 expressed in PS120 cells assessed as imposed acidosisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50248340BDBM50248340(N-(diaminomethylene)-2-(2,3-dichlorophenyl)-5-meth...)
Affinity DataIC50: 500nMAssay Description:Inhibition of human NHE1 expressed in PS120 cells assessed as imposed acidosisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50248342BDBM50248342(N-(diaminomethylene)-2-(3,5-dichlorophenyl)-5-meth...)
Affinity DataIC50: 520nMAssay Description:Inhibition of human NHE1 expressed in PS120 cells assessed as imposed acidosisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50248405BDBM50248405(N-(diaminomethylene)-2-(5-fluoro-2-methoxyphenyl)-...)
Affinity DataIC50: 800nMAssay Description:Inhibition of human NHE1 expressed in PS120 cells assessed as imposed acidosisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50248504BDBM50248504(N-(diaminomethylene)-2-(3,5-dichlorophenyl)-5-meth...)
Affinity DataIC50: 890nMAssay Description:Inhibition of human NHE1 expressed in PS120 cells assessed as imposed acidosisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50248174BDBM50248174(N-(diaminomethylene)-2-(2,5-dimethylphenyl)-5-meth...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human NHE1 expressed in PS120 cells assessed as imposed acidosisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50058759BDBM50058759(CHEMBL436559 | N-(diaminomethylene)-4-isopropyl-3-...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human NHE1 expressed in PS120 cells assessed as imposed acidosisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50248286BDBM50248286(2-(2-chlorophenyl)-N-(diaminomethylene)-5-methyl-1...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human NHE1 expressed in PS120 cells assessed as imposed acidosisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50248461BDBM50248461(2-(3-chlorophenyl)-N-(diaminomethylene)-5-methylox...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human NHE1 expressed in PS120 cells assessed as imposed acidosisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50248221BDBM50248221(N-(diaminomethylene)-2-(3,4-dimethoxyphenyl)-5-met...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of human NHE1 expressed in PS120 cells assessed as imposed acidosisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50248143BDBM50248143(N-(diaminomethylene)-5-methyl-2-o-tolyl-1H-imidazo...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human NHE1 expressed in PS120 cells assessed as imposed acidosisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50248285BDBM50248285(N-(diaminomethylene)-2-(3,5-difluorophenyl)-5-meth...)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of human NHE1 expressed in PS120 cells assessed as imposed acidosisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50248459BDBM50248459(N-(diaminomethylene)-2-(2,5-difluorophenyl)-5-meth...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of human NHE1 expressed in PS120 cells assessed as imposed acidosisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50248284BDBM50248284(N-(diaminomethylene)-2-(2,5-difluorophenyl)-5-meth...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human NHE1 expressed in PS120 cells assessed as imposed acidosisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50248176BDBM50248176(N-(diaminomethylene)-2-(2-methoxyphenyl)-5-methyl-...)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of human NHE1 expressed in PS120 cells assessed as imposed acidosisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50248460BDBM50248460(N-(diaminomethylene)-2-(3,5-difluorophenyl)-5-meth...)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of human NHE1 expressed in PS120 cells assessed as imposed acidosisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50248177BDBM50248177(N-(diaminomethylene)-2-(3-methoxyphenyl)-5-methyl-...)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of human NHE1 expressed in PS120 cells assessed as imposed acidosisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50248458BDBM50248458(N-(diaminomethylene)-2-(3-fluorophenyl)-5-methylox...)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of human NHE1 expressed in PS120 cells assessed as imposed acidosisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50248223BDBM50248223(N-(diaminomethylene)-2-(3-fluorophenyl)-5-methyl-1...)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of human NHE1 expressed in PS120 cells assessed as imposed acidosisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50248338BDBM50248338(2-(3-chlorophenyl)-N-(diaminomethylene)-5-methyl-1...)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of human NHE1 expressed in PS120 cells assessed as imposed acidosisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50248175BDBM50248175(N-(diaminomethylene)-2-(3,5-dimethylphenyl)-5-meth...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human NHE1 expressed in PS120 cells assessed as imposed acidosisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50248407BDBM50248407(N-(diaminomethylene)-5-methyl-2-m-tolyloxazole-4-c...)
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of human NHE1 expressed in PS120 cells assessed as imposed acidosisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50248283BDBM50248283(N-(diaminomethylene)-2-(2,3-difluorophenyl)-5-meth...)
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of human NHE1 expressed in PS120 cells assessed as imposed acidosisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50248457BDBM50248457(N-(diaminomethylene)-2-(3,5-dimethylphenyl)-5-meth...)
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of human NHE1 expressed in PS120 cells assessed as imposed acidosisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50248222BDBM50248222(N-(diaminomethylene)-2-(2-fluorophenyl)-5-methyl-1...)
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of human NHE1 expressed in PS120 cells assessed as imposed acidosisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50248406BDBM50248406(N-(diaminomethylene)-5-methyl-2-phenyloxazole-4-ca...)
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibition of human NHE1 expressed in PS120 cells assessed as imposed acidosisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50248142BDBM50248142(N-(diaminomethylene)-5-methyl-2-phenyl-1H-imidazol...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of human NHE1 expressed in PS120 cells assessed as imposed acidosisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50248144BDBM50248144(N-(diaminomethylene)-5-methyl-2-m-tolyl-1H-imidazo...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of human NHE1 expressed in PS120 cells assessed as imposed acidosisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50248339BDBM50248339(2-(4-chlorophenyl)-N-(diaminomethylene)-5-methyl-1...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human NHE1 expressed in PS120 cells assessed as imposed acidosisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50248145BDBM50248145(N-(diaminomethylene)-5-methyl-2-p-tolyl-1H-imidazo...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human NHE1 expressed in PS120 cells assessed as imposed acidosisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50248173BDBM50248173(N-(diaminomethylene)-2-(2,3-dimethylphenyl)-5-meth...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human NHE1 expressed in PS120 cells assessed as imposed acidosisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50248220BDBM50248220(N-(diaminomethylene)-2-(2,3-dimethoxyphenyl)-5-met...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human NHE1 expressed in PS120 cells assessed as imposed acidosisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50248219BDBM50248219(N-(diaminomethylene)-2-(4-methoxyphenyl)-5-methyl-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human NHE1 expressed in PS120 cells assessed as imposed acidosisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50248282BDBM50248282(N-(diaminomethylene)-2-(4-fluorophenyl)-5-methyl-1...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human NHE1 expressed in PS120 cells assessed as imposed acidosisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50248462BDBM50248462(2-(4-chlorophenyl)-N-(diaminomethylene)-5-methylox...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human NHE1 expressed in PS120 cells assessed as imposed acidosisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed