Compile Data Set for Download or QSAR
Report error Found 44 Enz. Inhib. hit(s) with all data for entry = 3132
LigandPNGBDBM28502((3R,5S)-5-{2-[4-({1-[(3-fluorophenyl)methyl]-1H-in...)
Affinity DataIC50: 30nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2009
Entry Details Article
PubMed
LigandPNGBDBM28502((3R,5S)-5-{2-[4-({1-[(3-fluorophenyl)methyl]-1H-in...)
Affinity DataIC50: 30nMAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2009
Entry Details Article
PubMed
LigandPNGBDBM28490((3R,5S)-5-[2-(4-{[3-chloro-4-(pyridin-2-ylmethoxy)...)
Affinity DataIC50: 30nMAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2009
Entry Details Article
PubMed
LigandPNGBDBM28503((3R,5S)-5-{2-[4-({1-[(2,5-difluorophenyl)methyl]-1...)
Affinity DataIC50: 33nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2009
Entry Details Article
PubMed
LigandPNGBDBM28503((3R,5S)-5-{2-[4-({1-[(2,5-difluorophenyl)methyl]-1...)
Affinity DataIC50: 35nMAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2009
Entry Details Article
PubMed
LigandPNGBDBM28490((3R,5S)-5-[2-(4-{[3-chloro-4-(pyridin-2-ylmethoxy)...)
Affinity DataIC50: 50nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2009
Entry Details Article
PubMed
LigandPNGBDBM28501((3R,5S)-5-(2-{4-[(1-benzyl-1H-indazol-5-yl)amino]t...)
Affinity DataIC50: 50nMAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2009
Entry Details Article
PubMed
LigandPNGBDBM28494((3R,5S)-5-[2-(4-{[3-chloro-4-(pyridin-2-yloxy)phen...)
Affinity DataIC50: 60nMAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2009
Entry Details Article
PubMed
LigandPNGBDBM28498((3R,5S)-5-(2-{4-[(4-benzylphenyl)amino]thieno[3,2-...)
Affinity DataIC50: 60nMAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2009
Entry Details Article
PubMed
LigandPNGBDBM28507((3R,5S)-5-(2-{4-[(1-benzyl-1H-indol-5-yl)amino]thi...)
Affinity DataIC50: 60nMAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2009
Entry Details Article
PubMed
LigandPNGBDBM28491((3R,5S)-5-[2-(4-{[3-chloro-4-(1,3-thiazol-4-ylmeth...)
Affinity DataIC50: 60nMAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2009
Entry Details Article
PubMed
LigandPNGBDBM28501((3R,5S)-5-(2-{4-[(1-benzyl-1H-indazol-5-yl)amino]t...)
Affinity DataIC50: 80nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2009
Entry Details Article
PubMed
LigandPNGBDBM28489(BMCL1921 Compound 6h | (3R,5S)-5-{2-[4-({3-chloro-...)
Affinity DataIC50: 80nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2009
Entry Details Article
PubMed
LigandPNGBDBM28489(BMCL1921 Compound 6h | (3R,5S)-5-{2-[4-({3-chloro-...)
Affinity DataIC50: 80nMAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2009
Entry Details Article
PubMed
LigandPNGBDBM28505((3R,5S)-5-{2-[4-({1-[(3-fluorobenzene)sulfonyl]-1H...)
Affinity DataIC50: 85nMAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2009
Entry Details Article
PubMed
LigandPNGBDBM28497((3R,5S)-5-[2-(4-{[(3-phenoxyphenyl)methyl]amino}th...)
Affinity DataIC50: 87nMAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2009
Entry Details Article
PubMed
LigandPNGBDBM28507((3R,5S)-5-(2-{4-[(1-benzyl-1H-indol-5-yl)amino]thi...)
Affinity DataIC50: 90nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2009
Entry Details Article
PubMed
LigandPNGBDBM28504((3R,5S)-5-{2-[4-({1-[1-(3-fluorophenyl)ethyl]-1H-i...)
Affinity DataIC50: 120nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2009
Entry Details Article
PubMed
LigandPNGBDBM28491((3R,5S)-5-[2-(4-{[3-chloro-4-(1,3-thiazol-4-ylmeth...)
Affinity DataIC50: 120nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2009
Entry Details Article
PubMed
LigandPNGBDBM28506((3R,5S)-5-[2-(4-{[1-(thiophene-2-sulfonyl)-1H-indo...)
Affinity DataIC50: 120nMAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2009
Entry Details Article
PubMed
LigandPNGBDBM28504((3R,5S)-5-{2-[4-({1-[1-(3-fluorophenyl)ethyl]-1H-i...)
Affinity DataIC50: 130nMAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2009
Entry Details Article
PubMed
LigandPNGBDBM28506((3R,5S)-5-[2-(4-{[1-(thiophene-2-sulfonyl)-1H-indo...)
Affinity DataIC50: 150nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2009
Entry Details Article
PubMed
LigandPNGBDBM28496((3R,5S)-5-{2-[4-({3-chloro-4-[(6-fluoroquinolin-4-...)
Affinity DataIC50: 180nMAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2009
Entry Details Article
PubMed
LigandPNGBDBM28497((3R,5S)-5-[2-(4-{[(3-phenoxyphenyl)methyl]amino}th...)
Affinity DataIC50: 180nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2009
Entry Details Article
PubMed
LigandPNGBDBM28509((3R,5S)-5-[2-(4-{[1-(1,3-thiazol-4-ylmethyl)-1H-in...)
Affinity DataIC50: 180nMAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2009
Entry Details Article
PubMed
LigandPNGBDBM28494((3R,5S)-5-[2-(4-{[3-chloro-4-(pyridin-2-yloxy)phen...)
Affinity DataIC50: 190nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2009
Entry Details Article
PubMed
LigandPNGBDBM28510((3R,5S)-5-(2-{4-[(1-benzyl-3-fluoro-1H-indol-5-yl)...)
Affinity DataIC50: 210nMAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2009
Entry Details Article
PubMed
LigandPNGBDBM28499((3R,5S)-5-[2-(4-{[4-(pyridin-2-ylsulfanyl)phenyl]a...)
Affinity DataIC50: 220nMAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2009
Entry Details Article
PubMed
LigandPNGBDBM28505((3R,5S)-5-{2-[4-({1-[(3-fluorobenzene)sulfonyl]-1H...)
Affinity DataIC50: 230nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2009
Entry Details Article
PubMed
LigandPNGBDBM28510((3R,5S)-5-(2-{4-[(1-benzyl-3-fluoro-1H-indol-5-yl)...)
Affinity DataIC50: 240nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2009
Entry Details Article
PubMed
LigandPNGBDBM28498((3R,5S)-5-(2-{4-[(4-benzylphenyl)amino]thieno[3,2-...)
Affinity DataIC50: 240nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2009
Entry Details Article
PubMed
LigandPNGBDBM28493((3R,5S)-5-[2-(4-{[5-(pyridin-2-yloxy)naphthalen-2-...)
Affinity DataIC50: 260nMAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2009
Entry Details Article
PubMed
LigandPNGBDBM28496((3R,5S)-5-{2-[4-({3-chloro-4-[(6-fluoroquinolin-4-...)
Affinity DataIC50: 280nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2009
Entry Details Article
PubMed
LigandPNGBDBM28495((3R,5S)-5-{2-[4-({3-chloro-4-[(5-methyl-1,2-oxazol...)
Affinity DataIC50: 370nMAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2009
Entry Details Article
PubMed
LigandPNGBDBM28495((3R,5S)-5-{2-[4-({3-chloro-4-[(5-methyl-1,2-oxazol...)
Affinity DataIC50: 400nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2009
Entry Details Article
PubMed
LigandPNGBDBM28492((3R,5S)-5-{2-[4-({6-[(3-fluorophenyl)methoxy]pyrid...)
Affinity DataIC50: 450nMAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2009
Entry Details Article
PubMed
LigandPNGBDBM28500((3R,5S)-5-{2-[4-({3-chloro-4-[(3-fluorophenyl)sulf...)
Affinity DataIC50: 630nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2009
Entry Details Article
PubMed
LigandPNGBDBM28509((3R,5S)-5-[2-(4-{[1-(1,3-thiazol-4-ylmethyl)-1H-in...)
Affinity DataIC50: 680nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2009
Entry Details Article
PubMed
LigandPNGBDBM28500((3R,5S)-5-{2-[4-({3-chloro-4-[(3-fluorophenyl)sulf...)
Affinity DataIC50: 800nMAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2009
Entry Details Article
PubMed
LigandPNGBDBM28493((3R,5S)-5-[2-(4-{[5-(pyridin-2-yloxy)naphthalen-2-...)
Affinity DataIC50: 1.05E+3nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2009
Entry Details Article
PubMed
LigandPNGBDBM28499((3R,5S)-5-[2-(4-{[4-(pyridin-2-ylsulfanyl)phenyl]a...)
Affinity DataIC50: 1.65E+3nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2009
Entry Details Article
PubMed
LigandPNGBDBM28492((3R,5S)-5-{2-[4-({6-[(3-fluorophenyl)methoxy]pyrid...)
Affinity DataIC50: 2.60E+3nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2009
Entry Details Article
PubMed
LigandPNGBDBM28508((3R,5S)-5-[2-(4-{[1-(2-phenylethyl)-1H-indol-5-yl]...)
Affinity DataIC50: 2.66E+3nMAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2009
Entry Details Article
PubMed
LigandPNGBDBM28508((3R,5S)-5-[2-(4-{[1-(2-phenylethyl)-1H-indol-5-yl]...)
Affinity DataIC50: 3.16E+3nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2009
Entry Details Article
PubMed