Compile Data Set for Download or QSAR
maximum 50k data
Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 50030232
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Liverpool

Curated by ChEMBL
LigandPNGBDBM79214(1-[1,3-bis(chloranyl)-6-(trifluoromethyl)phenanthr...)
Affinity DataIC50:  40nMAssay Description:Inhibition of human cloned ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank


TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Liverpool

Curated by ChEMBL
LigandPNGBDBM50041457(4-[(7-chloroquinolin-4-yl)amino]-2-[(diethylamino)...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of human cloned ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Liverpool

Curated by ChEMBL
LigandPNGBDBM22985(Aralen | CHEMBL76 | CHLOROQUINE PHOSPHATE | Chloro...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of human cloned ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 2C8(Human)
University of Liverpool

Curated by ChEMBL
LigandPNGBDBM50041457(4-[(7-chloroquinolin-4-yl)amino]-2-[(diethylamino)...)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of human recombinant CYP2C8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank


TargetCytochrome P450 2D6(Human)
University of Liverpool

Curated by ChEMBL
LigandPNGBDBM50134936(2-(tert-Butylamino-methyl)-5-(7-chloro-quinolin-4-...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of human recombinant CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 2D6(Human)
University of Liverpool

Curated by ChEMBL
LigandPNGBDBM50134934(5-(7-Chloro-quinolin-4-ylamino)-2-ethylaminomethyl...)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of human recombinant CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Liverpool

Curated by ChEMBL
LigandPNGBDBM50134931(5-(7-Chloro-quinolin-4-ylamino)-2-diethylaminometh...)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of human cloned ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 2D6(Human)
University of Liverpool

Curated by ChEMBL
LigandPNGBDBM50041457(4-[(7-chloroquinolin-4-yl)amino]-2-[(diethylamino)...)
Affinity DataIC50:  6.10E+3nMAssay Description:Inhibition of human recombinant CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 2D6(Human)
University of Liverpool

Curated by ChEMBL
LigandPNGBDBM50056190(4-(7-Chloro-quinolin-4-ylamino)-2-ethylaminomethyl...)
Affinity DataIC50:  6.40E+3nMAssay Description:Inhibition of human recombinant CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 2D6(Human)
University of Liverpool

Curated by ChEMBL
LigandPNGBDBM50134931(5-(7-Chloro-quinolin-4-ylamino)-2-diethylaminometh...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of human recombinant CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Liverpool

Curated by ChEMBL
LigandPNGBDBM50134936(2-(tert-Butylamino-methyl)-5-(7-chloro-quinolin-4-...)
Affinity DataIC50:  7.50E+3nMAssay Description:Inhibition of human cloned ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 1A2(Human)
University of Liverpool

Curated by ChEMBL
LigandPNGBDBM50134934(5-(7-Chloro-quinolin-4-ylamino)-2-ethylaminomethyl...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of human recombinant CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Liverpool

Curated by ChEMBL
LigandPNGBDBM50056190(4-(7-Chloro-quinolin-4-ylamino)-2-ethylaminomethyl...)
Affinity DataIC50:  9.50E+3nMAssay Description:Inhibition of human cloned ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 2C8(Human)
University of Liverpool

Curated by ChEMBL
LigandPNGBDBM50134931(5-(7-Chloro-quinolin-4-ylamino)-2-diethylaminometh...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of human recombinant CYP2C8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 1A2(Human)
University of Liverpool

Curated by ChEMBL
LigandPNGBDBM50041457(4-[(7-chloroquinolin-4-yl)amino]-2-[(diethylamino)...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of human recombinant CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 2C8(Human)
University of Liverpool

Curated by ChEMBL
LigandPNGBDBM50056190(4-(7-Chloro-quinolin-4-ylamino)-2-ethylaminomethyl...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of human recombinant CYP2C8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 2C8(Human)
University of Liverpool

Curated by ChEMBL
LigandPNGBDBM50134934(5-(7-Chloro-quinolin-4-ylamino)-2-ethylaminomethyl...)
Affinity DataIC50:  2.30E+4nMAssay Description:Inhibition of human recombinant CYP2C8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 2C8(Human)
University of Liverpool

Curated by ChEMBL
LigandPNGBDBM50134936(2-(tert-Butylamino-methyl)-5-(7-chloro-quinolin-4-...)
Affinity DataIC50:  2.30E+4nMAssay Description:Inhibition of human recombinant CYP2C8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 1A2(Human)
University of Liverpool

Curated by ChEMBL
LigandPNGBDBM50134931(5-(7-Chloro-quinolin-4-ylamino)-2-diethylaminometh...)
Affinity DataIC50:  2.30E+4nMAssay Description:Inhibition of human recombinant CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 3A4(Human)
University of Liverpool

Curated by ChEMBL
LigandPNGBDBM50056190(4-(7-Chloro-quinolin-4-ylamino)-2-ethylaminomethyl...)
Affinity DataIC50:  2.40E+4nMAssay Description:Inhibition of human recombinant CYP3A4 using N-N,diethyl-formamide as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 2C19(Human)
University of Liverpool

Curated by ChEMBL
LigandPNGBDBM50134936(2-(tert-Butylamino-methyl)-5-(7-chloro-quinolin-4-...)
Affinity DataIC50:  2.40E+4nMAssay Description:Inhibition of human recombinant CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 1A2(Human)
University of Liverpool

Curated by ChEMBL
LigandPNGBDBM50056190(4-(7-Chloro-quinolin-4-ylamino)-2-ethylaminomethyl...)
Affinity DataIC50:  2.80E+4nMAssay Description:Inhibition of human recombinant CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 3A4(Human)
University of Liverpool

Curated by ChEMBL
LigandPNGBDBM50041457(4-[(7-chloroquinolin-4-yl)amino]-2-[(diethylamino)...)
Affinity DataIC50:  2.80E+4nMAssay Description:Inhibition of human recombinant CYP3A4 using N-N,diethyl-formamide as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 1A2(Human)
University of Liverpool

Curated by ChEMBL
LigandPNGBDBM50134936(2-(tert-Butylamino-methyl)-5-(7-chloro-quinolin-4-...)
Affinity DataIC50:  2.90E+4nMAssay Description:Inhibition of human recombinant CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 2C19(Human)
University of Liverpool

Curated by ChEMBL
LigandPNGBDBM50134931(5-(7-Chloro-quinolin-4-ylamino)-2-diethylaminometh...)
Affinity DataIC50:  3.90E+4nMAssay Description:Inhibition of human recombinant CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 2C19(Human)
University of Liverpool

Curated by ChEMBL
LigandPNGBDBM50056190(4-(7-Chloro-quinolin-4-ylamino)-2-ethylaminomethyl...)
Affinity DataIC50:  5.40E+4nMAssay Description:Inhibition of human recombinant CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 2C9(Human)
University of Liverpool

Curated by ChEMBL
LigandPNGBDBM50056190(4-(7-Chloro-quinolin-4-ylamino)-2-ethylaminomethyl...)
Affinity DataIC50:  5.80E+4nMAssay Description:Inhibition of human recombinant CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 2C19(Human)
University of Liverpool

Curated by ChEMBL
LigandPNGBDBM50134934(5-(7-Chloro-quinolin-4-ylamino)-2-ethylaminomethyl...)
Affinity DataIC50:  6.20E+4nMAssay Description:Inhibition of human recombinant CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 2C9(Human)
University of Liverpool

Curated by ChEMBL
LigandPNGBDBM50041457(4-[(7-chloroquinolin-4-yl)amino]-2-[(diethylamino)...)
Affinity DataIC50:  6.20E+4nMAssay Description:Inhibition of human recombinant CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank


TargetCytochrome P450 2C9(Human)
University of Liverpool

Curated by ChEMBL
LigandPNGBDBM50134931(5-(7-Chloro-quinolin-4-ylamino)-2-diethylaminometh...)
Affinity DataIC50:  7.50E+4nMAssay Description:Inhibition of human recombinant CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 3A4(Human)
University of Liverpool

Curated by ChEMBL
LigandPNGBDBM50056190(4-(7-Chloro-quinolin-4-ylamino)-2-ethylaminomethyl...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant CYP3A4 using phenylpiperazinylmethylbenzylresofurin as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 3A4(Human)
University of Liverpool

Curated by ChEMBL
LigandPNGBDBM50134936(2-(tert-Butylamino-methyl)-5-(7-chloro-quinolin-4-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant CYP3A4 using phenylpiperazinylmethylbenzylresofurin as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 3A4(Human)
University of Liverpool

Curated by ChEMBL
LigandPNGBDBM50134931(5-(7-Chloro-quinolin-4-ylamino)-2-diethylaminometh...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant CYP3A4 using phenylpiperazinylmethylbenzylresofurin as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 3A4(Human)
University of Liverpool

Curated by ChEMBL
LigandPNGBDBM50041457(4-[(7-chloroquinolin-4-yl)amino]-2-[(diethylamino)...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant CYP3A4 using phenylpiperazinylmethylbenzylresofurin as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 3A4(Human)
University of Liverpool

Curated by ChEMBL
LigandPNGBDBM50134934(5-(7-Chloro-quinolin-4-ylamino)-2-ethylaminomethyl...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant CYP3A4 using N-N,diethyl-formamide as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 2C9(Human)
University of Liverpool

Curated by ChEMBL
LigandPNGBDBM50134934(5-(7-Chloro-quinolin-4-ylamino)-2-ethylaminomethyl...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed