Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50038792
TargetSodium/glucose cotransporter 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM20880(CHEMBL429910 | C-aryl glucoside, 6 | BMS-512148 | ...)
Affinity DataEC50:  1.10nMAssay Description:Inhibition of human kidney SGLT2 assessed as renal glucose reabsorptionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium/glucose cotransporter 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50257797((2S,3R,4R,5S,6R)-2-(2-(4-ethylbenzyl)phenyl)-6-(hy...)
Affinity DataEC50: >2nMAssay Description:Inhibition of human kidney SGLT2 assessed as renal glucose reabsorptionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM20878((2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-{2-[(4-methox...)
Affinity DataKi:  2.40nMAssay Description:Inhibition of human kidney SGLT2 assessed as renal glucose reabsorptionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM20878((2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-{2-[(4-methox...)
Affinity DataKi:  2.40nMAssay Description:Inhibition of human kidney SGLT2 assessed as renal glucose reabsorptionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Rat)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM20880(CHEMBL429910 | C-aryl glucoside, 6 | BMS-512148 | ...)
Affinity DataEC50:  3nMAssay Description:Inhibition of rat SGLT2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium/glucose cotransporter 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM20877(CHEMBL183937 | JMC511145 Compound 2 | 3-(1-benzofu...)
Affinity DataEC50:  6.60nMAssay Description:Inhibition of human kidney SGLT2 assessed as renal glucose reabsorptionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50257747(remogliflozin | CHEMBL494322)
Affinity DataKi:  12nMAssay Description:Inhibition of human kidney SGLT2 assessed as renal glucose reabsorptionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50257747(remogliflozin | CHEMBL494322)
Affinity DataKi:  12nMAssay Description:Inhibition of human kidney SGLT2 assessed as renal glucose reabsorptionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM20875(CHEMBL245067 | JMC511145 Compound 1 | 1-(2,4-dihyd...)
Affinity DataKi:  19nMAssay Description:Inhibition of human kidney SGLT2 assessed as renal glucose reabsorptionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium/glucose cotransporter 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50245105((2R,3S,4R,5R,6S)-2-(hydroxymethyl)-6-(3-(4-methylb...)
Affinity DataEC50:  22nMAssay Description:Inhibition of human kidney SGLT2 assessed as renal glucose reabsorptionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM20875(CHEMBL245067 | JMC511145 Compound 1 | 1-(2,4-dihyd...)
Affinity DataEC50:  35nMAssay Description:Inhibition of human kidney SGLT2 assessed as renal glucose reabsorptionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium/glucose cotransporter 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM20877(CHEMBL183937 | JMC511145 Compound 2 | 3-(1-benzofu...)
Affinity DataIC50: 50nMAssay Description:Inhibition of human kidney SGLT2 assessed as renal glucose reabsorptionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM20879(CHEMBL429911 | N-ethyl-2,6-dihydroxy-5-[(4-methoxy...)
Affinity DataEC50:  500nMAssay Description:Inhibition of human kidney SGLT2 assessed as renal glucose reabsorptionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2012
Entry Details Article
PubMed