Compile Data Set for Download or QSAR
Report error Found 35 Enz. Inhib. hit(s) with all data for entry = 3119
LigandChemical structure of BindingDB Monomer ID 28339BDBM28339((1R,2S)-1-{[4-(4-chlorophenyl)benzene][2-(7H-purin...)
Affinity DataIC50: 71nMAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 28337BDBM28337((1R,2S)-1-{[4-(4-chlorophenyl)benzene]({2-[4-(meth...)
Affinity DataIC50: 73nMAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 28327BDBM28327((1R,2S)-1-{[4-(4-chlorophenyl)benzene][2-(3-methox...)
Affinity DataIC50: 78nMpH: 7.5 T: 2°CAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 28340BDBM28340((1R,2S)-1-{[4-(4-chlorophenyl)benzene][2-(9H-purin...)
Affinity DataIC50: 170nMAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 28332BDBM28332((1R,2S)-1-{[4-(4-chlorophenyl)benzene][2-(1H-1,2,4...)
Affinity DataIC50: 180nMAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 28326BDBM28326((1R,2S)-1-{[4-(4-chlorophenyl)benzene][2-(2-oxo-1,...)
Affinity DataIC50: 180nMpH: 7.5 T: 2°CAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 28333BDBM28333((1R,2S)-1-{[4-(4-chlorophenyl)benzene][2-(4H-1,2,4...)
Affinity DataIC50: 190nMAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 28314BDBM28314((1R,2S)-1-{[4-(4-chlorophenyl)benzene][2-(2-oxopyr...)
Affinity DataIC50: 200nMpH: 7.5 T: 2°CAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 28325BDBM28325((1R,2S)-1-{[4-(4-chlorophenyl)benzene][2-(2-oxopip...)
Affinity DataIC50: 210nMpH: 7.5 T: 2°CAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 28324BDBM28324((1R,2S)-1-{[4-(4-chlorophenyl)benzene][2-(2-oxo-1,...)
Affinity DataIC50: 220nMpH: 7.5 T: 2°CAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 28338BDBM28338((1R,2S)-1-{[4-(4-chlorophenyl)benzene]({2-[5-(meth...)
Affinity DataIC50: 230nMAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 28334BDBM28334((1R,2S)-1-{[4-(4-chlorophenyl)benzene][2-(2H-1,2,3...)
Affinity DataIC50: 260nMAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 28335BDBM28335((1R,2S)-1-{[4-(4-chlorophenyl)benzene][2-(1H-1,2,3...)
Affinity DataIC50: 270nMAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 28336BDBM28336((1R,2S)-1-{[4-(4-chlorophenyl)benzene][2-(1H-1,2,3...)
Affinity DataIC50: 270nMAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 28329BDBM28329((1R,2S)-1-{[4-(4-chlorophenyl)benzene][2-(pyridin-...)
Affinity DataIC50: 290nMAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 28323BDBM28323((1R,2S)-1-{[4-(4-chlorophenyl)benzene][2-(2,5-diox...)
Affinity DataIC50: 310nMpH: 7.5 T: 2°CAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 28331BDBM28331((1R,2S)-1-{[4-(4-chlorophenyl)benzene][2-(1H-imida...)
Affinity DataIC50: 320nMAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 28328BDBM28328((1R,2S)-1-{[4-(4-chlorophenyl)benzene][2-(pyridin-...)
Affinity DataIC50: 750nMpH: 7.5 T: 2°CAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 28330BDBM28330((1R,2S)-1-{[4-(4-chlorophenyl)benzene][2-(pyridin-...)
Affinity DataIC50: 820nMAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 28316BDBM28316((1R,2S)-1-({[4-(4-chlorophenyl)-1,2,3,6-tetrahydro...)
Affinity DataIC50: 880nMpH: 7.5 T: 2°CAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 28317BDBM28317((1R,2S)-1-{[6-(4-chlorophenyl)pyridine-3-][2-(2-ox...)
Affinity DataIC50: 1.10E+3nMpH: 7.5 T: 2°CAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 28313BDBM28313((2R)-2-{[4-(4-chlorophenyl)benzene][2-(2-oxopyrrol...)
Affinity DataIC50: 1.60E+3nMpH: 7.5 T: 2°CAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 28306BDBM28306((2R)-2-{[4-(4-chlorophenyl)benzene]sulfonamido}-3-...)
Affinity DataIC50: 3.20E+3nMpH: 7.5 T: 2°CAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 28319BDBM28319((1R,2S)-1-{[4-(4-acetamidophenyl)benzene][2-(2-oxo...)
Affinity DataIC50: 4.50E+3nMpH: 7.5 T: 2°CAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 28318BDBM28318((1R,2S)-1-({4-[4-(dimethylamino)phenyl]benzene}[2-...)
Affinity DataIC50: 6.60E+3nMpH: 7.5 T: 2°CAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 28312BDBM28312((2R)-2-{[4-(4-chlorophenyl)benzene](2-phenylethyl)...)
Affinity DataIC50: 7.30E+3nMpH: 7.5 T: 2°CAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 28307BDBM28307((2R)-2-{[4-(4-chlorophenyl)benzene](methyl)sulfona...)
Affinity DataIC50: 8.00E+3nMpH: 7.5 T: 2°CAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 28315BDBM28315((2R)-2-{[4-(4-chlorophenyl)benzene][2-(2-oxopyrrol...)
Affinity DatapH: 7.5 T: 2°CAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 28320BDBM28320((1R,2S)-1-{[2-(2-oxopyrrolidin-1-yl)ethyl][4-(pyri...)
Affinity DatapH: 7.5 T: 2°CAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 28321BDBM28321((1R,2S)-1-{[4-(3-hydroxyprop-1-yn-1-yl)benzene][2-...)
Affinity DatapH: 7.5 T: 2°CAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 28322BDBM28322((1R,2S)-1-{[4-(3-methoxyprop-1-yn-1-yl)benzene][2-...)
Affinity DatapH: 7.5 T: 2°CAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 28308BDBM28308((2S)-2-{[4-(4-chlorophenyl)benzene](methyl)sulfona...)
Affinity DatapH: 7.5 T: 2°CAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 28309BDBM28309((2R)-2-{[4-(4-chlorophenyl)benzene](cyclopropylmet...)
Affinity DatapH: 7.5 T: 2°CAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 28310BDBM28310((2R)-2-{[4-(4-chlorophenyl)benzene](cyclohexylmeth...)
Affinity DatapH: 7.5 T: 2°CAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 28311BDBM28311((2R)-2-{benzyl[4-(4-chlorophenyl)benzene]sulfonami...)
Affinity DatapH: 7.5 T: 2°CAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2009
Entry Details Article
PubMed