Report error Found 38 Enz. Inhib. hit(s) with all data for entry = 3264
Affinity DataKi: 1.10nM ΔG°: -50.6kJ/mole EC50: 2.30nMpH: 7.4 T: 22°CAssay Description:Binding affinity of each compound was measured by assessing the potency of inhibition of binding of radiolabeled RTI-55. Membranes were preincubated ...More data for this Ligand-Target Pair
Affinity DataKi: 1.10nM ΔG°: -50.6kJ/mole EC50: 7.30nMpH: 7.4 T: 22°CAssay Description:Binding affinity of each compound was measured by assessing the potency of inhibition of binding of radiolabeled RTI-55. Membranes were preincubated ...More data for this Ligand-Target Pair
Affinity DataKi: 1.20nM ΔG°: -52.5kJ/molepH: 8.0 T: 34°CAssay Description:The samples were assayed in a solution composed of PDE4, [3H]cAMP/cAMP, and test compounds. To convert AMP to adenosine, snake venom was added to eac...More data for this Ligand-Target Pair
Affinity DataKi: 2nM ΔG°: -51.1kJ/molepH: 8.0 T: 34°CAssay Description:The samples were assayed in a solution composed of PDE4, [3H]cAMP/cAMP, and test compounds. To convert AMP to adenosine, snake venom was added to eac...More data for this Ligand-Target Pair
Affinity DataKi: 2.10nM ΔG°: -49.0kJ/mole EC50: 2.5nMpH: 7.4 T: 22°CAssay Description:Binding affinity of each compound was measured by assessing the potency of inhibition of binding of radiolabeled RTI-55. Membranes were preincubated ...More data for this Ligand-Target Pair
Affinity DataKi: 2.30nM ΔG°: -50.8kJ/molepH: 8.0 T: 34°CAssay Description:The samples were assayed in a solution composed of PDE4, [3H]cAMP/cAMP, and test compounds. To convert AMP to adenosine, snake venom was added to eac...More data for this Ligand-Target Pair
Affinity DataKi: 6.30nM ΔG°: -48.2kJ/molepH: 8.0 T: 34°CAssay Description:The samples were assayed in a solution composed of PDE4, [3H]cAMP/cAMP, and test compounds. To convert AMP to adenosine, snake venom was added to eac...More data for this Ligand-Target Pair
Affinity DataKi: 21.2nM ΔG°: -43.4kJ/mole EC50: 18.4nMpH: 7.4 T: 22°CAssay Description:Binding affinity of each compound was measured by assessing the potency of inhibition of binding of radiolabeled RTI-55. Membranes were preincubated ...More data for this Ligand-Target Pair
Affinity DataKi: 58.9nM ΔG°: -42.5kJ/molepH: 8.0 T: 34°CAssay Description:The samples were assayed in a solution composed of PDE4, [3H]cAMP/cAMP, and test compounds. To convert AMP to adenosine, snake venom was added to eac...More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataKi: 156nM ΔG°: -38.5kJ/mole EC50: 127nMpH: 7.4 T: 22°CAssay Description:Binding affinity of each compound was measured by assessing the potency of inhibition of binding of radiolabeled RTI-55. Membranes were preincubated ...More data for this Ligand-Target Pair
Affinity DataKi: 194nM ΔG°: -37.9kJ/mole EC50: 194nMpH: 7.4 T: 22°CAssay Description:Binding affinity of each compound was measured by assessing the potency of inhibition of binding of radiolabeled RTI-55. Membranes were preincubated ...More data for this Ligand-Target Pair
Affinity DataKi: 199nM ΔG°: -39.4kJ/molepH: 8.0 T: 34°CAssay Description:The samples were assayed in a solution composed of PDE4, [3H]cAMP/cAMP, and test compounds. To convert AMP to adenosine, snake venom was added to eac...More data for this Ligand-Target Pair
Affinity DataKi: 250nM ΔG°: -38.8kJ/molepH: 8.0 T: 34°CAssay Description:The samples were assayed in a solution composed of PDE4, [3H]cAMP/cAMP, and test compounds. To convert AMP to adenosine, snake venom was added to eac...More data for this Ligand-Target Pair
Affinity DataKi: 276nM ΔG°: -37.1kJ/mole EC50: 416nMpH: 7.4 T: 22°CAssay Description:Binding affinity of each compound was measured by assessing the potency of inhibition of binding of radiolabeled RTI-55. Membranes were preincubated ...More data for this Ligand-Target Pair
Affinity DataKi: 371nM ΔG°: -36.3kJ/mole EC50: 303nMpH: 7.4 T: 22°CAssay Description:Binding affinity of each compound was measured by assessing the potency of inhibition of binding of radiolabeled RTI-55. Membranes were preincubated ...More data for this Ligand-Target Pair
Affinity DataKi: 500nM ΔG°: -37.0kJ/molepH: 8.0 T: 34°CAssay Description:The samples were assayed in a solution composed of PDE4, [3H]cAMP/cAMP, and test compounds. To convert AMP to adenosine, snake venom was added to eac...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nM ΔG°: >-35.3kJ/molepH: 8.0 T: 34°CAssay Description:The samples were assayed in a solution composed of PDE4, [3H]cAMP/cAMP, and test compounds. To convert AMP to adenosine, snake venom was added to eac...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nM ΔG°: >-35.3kJ/molepH: 8.0 T: 34°CAssay Description:The samples were assayed in a solution composed of PDE4, [3H]cAMP/cAMP, and test compounds. To convert AMP to adenosine, snake venom was added to eac...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nM ΔG°: >-35.3kJ/molepH: 8.0 T: 34°CAssay Description:The samples were assayed in a solution composed of PDE4, [3H]cAMP/cAMP, and test compounds. To convert AMP to adenosine, snake venom was added to eac...More data for this Ligand-Target Pair
Affinity DataKi: 1.12E+3nM EC50: 835nMAssay Description:Binding affinity of each compound was measured by assessing the potency of inhibition of binding of radiolabeled RTI-55. Membranes were preincubated ...More data for this Ligand-Target Pair
Affinity DataKi: 1.56E+3nM EC50: 1.02E+3nMAssay Description:Binding affinity of each compound was measured by assessing the potency of inhibition of binding of radiolabeled RTI-55. Membranes were preincubated ...More data for this Ligand-Target Pair
Affinity DataKi: 1.75E+3nM EC50: 957nMAssay Description:Binding affinity of each compound was measured by assessing the potency of inhibition of binding of radiolabeled RTI-55. Membranes were preincubated ...More data for this Ligand-Target Pair
Affinity DataKi: 2.44E+3nM EC50: 481nMAssay Description:Binding affinity of each compound was measured by assessing the potency of inhibition of binding of radiolabeled RTI-55. Membranes were preincubated ...More data for this Ligand-Target Pair
Affinity DataKi: 2.48E+3nM ΔG°: -31.7kJ/mole EC50: 3.56E+3nMpH: 7.4 T: 22°CAssay Description:Binding affinity of each compound was measured by assessing the potency of inhibition of binding of radiolabeled RTI-55. Membranes were preincubated ...More data for this Ligand-Target Pair
Affinity DataKi: 5.34E+3nM ΔG°: -29.8kJ/mole EC50: 5.34E+3nMpH: 7.4 T: 22°CAssay Description:Binding affinity of each compound was measured by assessing the potency of inhibition of binding of radiolabeled RTI-55. Membranes were preincubated ...More data for this Ligand-Target Pair
Affinity DataKi: 6.50E+3nM ΔG°: -29.3kJ/mole EC50: 2.79E+4nMpH: 7.4 T: 22°CAssay Description:Binding affinity of each compound was measured by assessing the potency of inhibition of binding of radiolabeled RTI-55. Membranes were preincubated ...More data for this Ligand-Target Pair
Affinity DataKi: 6.67E+3nM ΔG°: -29.2kJ/mole EC50: 1.95E+4nMpH: 7.4 T: 22°CAssay Description:Binding affinity of each compound was measured by assessing the potency of inhibition of binding of radiolabeled RTI-55. Membranes were preincubated ...More data for this Ligand-Target Pair
Affinity DataKi: 7.31E+3nM ΔG°: -29.0kJ/mole EC50: 1.70E+4nMpH: 7.4 T: 22°CAssay Description:Binding affinity of each compound was measured by assessing the potency of inhibition of binding of radiolabeled RTI-55. Membranes were preincubated ...More data for this Ligand-Target Pair
Affinity DataKi: 7.44E+3nM EC50: 7.44E+3nMAssay Description:Binding affinity of each compound was measured by assessing the potency of inhibition of binding of radiolabeled RTI-55. Membranes were preincubated ...More data for this Ligand-Target Pair
Affinity DataKi: 1.06E+4nM EC50: 1.93E+3nMAssay Description:Binding affinity of each compound was measured by assessing the potency of inhibition of binding of radiolabeled RTI-55. Membranes were preincubated ...More data for this Ligand-Target Pair
Affinity DataKi: 1.93E+4nM EC50: 2.04E+4nMAssay Description:Binding affinity of each compound was measured by assessing the potency of inhibition of binding of radiolabeled RTI-55. Membranes were preincubated ...More data for this Ligand-Target Pair
Affinity DataKi: 3.91E+4nM EC50: >1.00E+5nMAssay Description:Binding affinity of each compound was measured by assessing the potency of inhibition of binding of radiolabeled RTI-55. Membranes were preincubated ...More data for this Ligand-Target Pair
Affinity DataKi: 6.70E+4nM ΔG°: -23.6kJ/mole EC50: >1.00E+5nMpH: 7.4 T: 22°CAssay Description:Binding affinity of each compound was measured by assessing the potency of inhibition of binding of radiolabeled RTI-55. Membranes were preincubated ...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+5nM EC50: >1.00E+5nMAssay Description:Binding affinity of each compound was measured by assessing the potency of inhibition of binding of radiolabeled RTI-55. Membranes were preincubated ...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+5nM ΔG°: >-22.6kJ/mole EC50: >1.00E+5nMpH: 7.4 T: 22°CAssay Description:Binding affinity of each compound was measured by assessing the potency of inhibition of binding of radiolabeled RTI-55. Membranes were preincubated ...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+5nM ΔG°: >-22.6kJ/mole EC50: >1.00E+5nMpH: 7.4 T: 22°CAssay Description:Binding affinity of each compound was measured by assessing the potency of inhibition of binding of radiolabeled RTI-55. Membranes were preincubated ...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+5nM ΔG°: >-22.6kJ/mole EC50: >1.00E+5nMpH: 7.4 T: 22°CAssay Description:Binding affinity of each compound was measured by assessing the potency of inhibition of binding of radiolabeled RTI-55. Membranes were preincubated ...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+5nM ΔG°: >-22.6kJ/mole EC50: >1.00E+5nMpH: 7.4 T: 22°CAssay Description:Binding affinity of each compound was measured by assessing the potency of inhibition of binding of radiolabeled RTI-55. Membranes were preincubated ...More data for this Ligand-Target Pair
