Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50028376
TargetStromelysin-1(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50241504BDBM50241504(AM-2 | CHEMBL255374 | N-(biphenyl-4-ylmethyl)-3-hy...)
Affinity DataIC50: 240nMAssay Description:Inhibition of human MMP3 catalytic domain by fluorescent substrate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetStromelysin-1(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50278741BDBM50278741(3-Hydroxy-6-methyl-4-oxo-4H-pyran-2-carboxylic aci...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human MMP3 catalytic domain by fluorescent substrate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetStromelysin-1(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50278742BDBM50278742(3-Hydroxy-6-methyl-4-oxo-4H-pyran-2-carboxylic aci...)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of human MMP3 catalytic domain by fluorescent substrate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetStromelysin-1(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50278743BDBM50278743(AM-2S | N-(biphenyl-4-ylmethyl)-3-hydroxy-6-methyl...)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of human MMP3 catalytic domain by fluorescent substrate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50241504BDBM50241504(AM-2 | CHEMBL255374 | N-(biphenyl-4-ylmethyl)-3-hy...)
Affinity DataIC50: 9.30E+3nMAssay Description:Inhibition of human MMP2 catalytic domain by fluorescent substrate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetStromelysin-1(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50278812BDBM50278812(5-Hydroxy-4-thioxo-4H-pyran-2-carboxylic acid (bip...)
Affinity DataIC50: 1.33E+4nMAssay Description:Inhibition of human MMP3 catalytic domain by fluorescent substrate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetStromelysin-1(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50278813BDBM50278813(5-Hydroxy-4-thioxo-4H-pyran-2-carboxylic acid 4-me...)
Affinity DataIC50: 1.39E+4nMAssay Description:Inhibition of human MMP3 catalytic domain by fluorescent substrate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50278812BDBM50278812(5-Hydroxy-4-thioxo-4H-pyran-2-carboxylic acid (bip...)
Affinity DataIC50: 1.44E+4nMAssay Description:Inhibition of human MMP2 catalytic domain by fluorescent substrate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetStromelysin-1(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50278740BDBM50278740(3-Hydroxy-6-methyl-4-thioxo-4H-pyran-2-carboxylic ...)
Affinity DataIC50: 1.64E+4nMAssay Description:Inhibition of human MMP3 catalytic domain by fluorescent substrate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50278740BDBM50278740(3-Hydroxy-6-methyl-4-thioxo-4H-pyran-2-carboxylic ...)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of human MMP2 catalytic domain by fluorescent substrate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50278814BDBM50278814(N-(biphenyl-4-ylmethyl)-5-hydroxy-2-methyl-4-thiox...)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of human MMP2 catalytic domain by fluorescent substrate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50278740BDBM50278740(3-Hydroxy-6-methyl-4-thioxo-4H-pyran-2-carboxylic ...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human MMP1 catalytic domain by fluorescent substrate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50278070BDBM50278070(5-Hydroxy-2-methyl-4-thioxo-4H-pyran-3-carboxylic ...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human MMP2 catalytic domain by fluorescent substrate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50278130BDBM50278130(2-{[(Biphenyl-4-ylmethyl)-amino]-methyl}-3-hydroxy...)
Affinity DataIC50: 3.77E+4nMAssay Description:Inhibition of human MMP2 catalytic domain by fluorescent substrate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50278812BDBM50278812(5-Hydroxy-4-thioxo-4H-pyran-2-carboxylic acid (bip...)
Affinity DataIC50: 4.40E+4nMAssay Description:Inhibition of human MMP1 catalytic domain by fluorescent substrate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50241504BDBM50241504(AM-2 | CHEMBL255374 | N-(biphenyl-4-ylmethyl)-3-hy...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human MMP1 catalytic domain by fluorescent substrate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed