Compile Data Set for Download or QSAR
maximum 50k data
Found 30 Enz. Inhib. hit(s) with all data for entry = 50028386
TargetHistone deacetylase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50278466(CHEMBL470421 | pyridin-3-ylmethyl 4-(2-amino-5-(th...)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50278467(CHEMBL511473 | ethyl 4-(2-amino-5-(thiophen-2-yl)p...)
Affinity DataIC50:  6.5nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50278377(CHEMBL472636 | methyl 4-(2-amino-5-(thiophen-2-yl)...)
Affinity DataIC50:  7nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50278515(CHEMBL470225 | diethyl(4-(2-amino-5-(thiophen-2-yl...)
Affinity DataIC50:  7.70nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50278420(CHEMBL513536 | N-(2-amino-5-(thiophen-2-yl)phenyl)...)
Affinity DataIC50:  9nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50278470(CHEMBL513876 | N-(2-amino-5-(thiophen-2-yl)phenyl)...)
Affinity DataIC50:  11nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50278251(CHEMBL471031 | diethyl 4-(2-amino-5-(thiophen-2-yl...)
Affinity DataIC50:  13nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50278515(CHEMBL470225 | diethyl(4-(2-amino-5-(thiophen-2-yl...)
Affinity DataIC50:  14nMAssay Description:Inhibition of HDAC2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50278308(CHEMBL469557 | ethyl 4-(2-amino-5-(thiophen-2-yl)p...)
Affinity DataIC50:  14nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50278468(CHEMBL469377 | ethyl 4-(2-amino-5-(thiophen-2-yl)p...)
Affinity DataIC50:  16nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50278374(CHEMBL471453 | methyl 4-(2-amino-5-(thiophen-2-yl)...)
Affinity DataIC50:  20nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50278422(CHEMBL469368 | ethyl 4-(2-amino-5-(thiophen-2-yl)p...)
Affinity DataIC50:  21nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50278249(CHEMBL442563 | diethyl 4-(2-amino-5-(thiophen-2-yl...)
Affinity DataIC50:  22nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50278307(CHEMBL469342 | diethyl 3-(2-amino-5-(thiophen-2-yl...)
Affinity DataIC50:  23nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50278375(4-(2-amino-5-(thiophen-2-yl)phenylcarbamoyl)benzyl...)
Affinity DataIC50:  28nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50278309(CHEMBL471868 | methyl 4-(2-amino-5-(thiophen-2-yl)...)
Affinity DataIC50:  29nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50278306(CHEMBL513014 | ethyl hydrogen 4-(2-amino-5-(thioph...)
Affinity DataIC50:  38nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50278250(CHEMBL513255 | ethyl hydrogen 4-(2-amino-5-(thioph...)
Affinity DataIC50:  42nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50278423(CHEMBL469369 | methyl 4-(2-amino-5-(thiophen-2-yl)...)
Affinity DataIC50:  52nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50278469(CHEMBL469378 | methyl 4-(2-amino-5-(thiophen-2-yl)...)
Affinity DataIC50:  54nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50278419(CHEMBL512857 | methyl 3-(2-amino-5-(thiophen-2-yl)...)
Affinity DataIC50:  90nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50278376(CHEMBL471455 | methyl 3-(2-amino-5-(thiophen-2-yl)...)
Affinity DataIC50:  140nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50278421(CHEMBL469363 | N-(2-amino-5-(thiophen-2-yl)phenyl)...)
Affinity DataIC50:  270nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50278515(CHEMBL470225 | diethyl(4-(2-amino-5-(thiophen-2-yl...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of HDAC3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50278515(CHEMBL470225 | diethyl(4-(2-amino-5-(thiophen-2-yl...)
Affinity DataIC50:  3.70E+4nMAssay Description:Inhibition of HDAC8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50278515(CHEMBL470225 | diethyl(4-(2-amino-5-(thiophen-2-yl...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of HDAC5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50278515(CHEMBL470225 | diethyl(4-(2-amino-5-(thiophen-2-yl...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of HDAC4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50278515(CHEMBL470225 | diethyl(4-(2-amino-5-(thiophen-2-yl...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of HDAC7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 11(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50278515(CHEMBL470225 | diethyl(4-(2-amino-5-(thiophen-2-yl...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of HDAC11More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50278515(CHEMBL470225 | diethyl(4-(2-amino-5-(thiophen-2-yl...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of HDAC6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed