Compile Data Set for Download or QSAR
maximum 50k data
Found 26 Enz. Inhib. hit(s) with all data for entry = 50038795
TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of Liverpool

Curated by ChEMBL
LigandPNGBDBM50247629(CHEMBL453384 | N-(3-((tert-butylamino)methyl)-4-fl...)
Affinity DataIC50:  300nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C8(Homo sapiens (Human))
University Of Liverpool

Curated by ChEMBL
LigandPNGBDBM50041457(4-[(7-chloroquinolin-4-yl)amino]-2-[(diethylamino)...)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of human CYP2C8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of Liverpool

Curated by ChEMBL
LigandPNGBDBM50041457(4-[(7-chloroquinolin-4-yl)amino]-2-[(diethylamino)...)
Affinity DataIC50:  6.10E+3nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of Liverpool

Curated by ChEMBL
LigandPNGBDBM50056190(4-(7-Chloro-quinolin-4-ylamino)-2-ethylaminomethyl...)
Affinity DataIC50:  6.40E+3nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of Liverpool

Curated by ChEMBL
LigandPNGBDBM50134931(5-(7-Chloro-quinolin-4-ylamino)-2-diethylaminometh...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
University Of Liverpool

Curated by ChEMBL
LigandPNGBDBM50247629(CHEMBL453384 | N-(3-((tert-butylamino)methyl)-4-fl...)
Affinity DataIC50:  8.80E+3nMAssay Description:Inhibition of human CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C8(Homo sapiens (Human))
University Of Liverpool

Curated by ChEMBL
LigandPNGBDBM50247629(CHEMBL453384 | N-(3-((tert-butylamino)methyl)-4-fl...)
Affinity DataIC50:  9.80E+3nMAssay Description:Inhibition of human CYP2C8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C8(Homo sapiens (Human))
University Of Liverpool

Curated by ChEMBL
LigandPNGBDBM50134931(5-(7-Chloro-quinolin-4-ylamino)-2-diethylaminometh...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of human CYP2C8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
University Of Liverpool

Curated by ChEMBL
LigandPNGBDBM50041457(4-[(7-chloroquinolin-4-yl)amino]-2-[(diethylamino)...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of human CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C8(Homo sapiens (Human))
University Of Liverpool

Curated by ChEMBL
LigandPNGBDBM50056190(4-(7-Chloro-quinolin-4-ylamino)-2-ethylaminomethyl...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of human CYP2C8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
University Of Liverpool

Curated by ChEMBL
LigandPNGBDBM50134931(5-(7-Chloro-quinolin-4-ylamino)-2-diethylaminometh...)
Affinity DataIC50:  2.30E+4nMAssay Description:Inhibition of human CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
University Of Liverpool

Curated by ChEMBL
LigandPNGBDBM50056190(4-(7-Chloro-quinolin-4-ylamino)-2-ethylaminomethyl...)
Affinity DataIC50:  2.40E+4nMAssay Description:Inhibition of human CYP3A4 using DEF substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
University Of Liverpool

Curated by ChEMBL
LigandPNGBDBM50056190(4-(7-Chloro-quinolin-4-ylamino)-2-ethylaminomethyl...)
Affinity DataIC50:  2.80E+4nMAssay Description:Inhibition of human CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
University Of Liverpool

Curated by ChEMBL
LigandPNGBDBM50041457(4-[(7-chloroquinolin-4-yl)amino]-2-[(diethylamino)...)
Affinity DataIC50:  2.80E+4nMAssay Description:Inhibition of human CYP3A4 using DEF substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
University Of Liverpool

Curated by ChEMBL
LigandPNGBDBM50134931(5-(7-Chloro-quinolin-4-ylamino)-2-diethylaminometh...)
Affinity DataIC50:  3.90E+4nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
University Of Liverpool

Curated by ChEMBL
LigandPNGBDBM50247629(CHEMBL453384 | N-(3-((tert-butylamino)methyl)-4-fl...)
Affinity DataIC50:  5.20E+4nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
University Of Liverpool

Curated by ChEMBL
LigandPNGBDBM50056190(4-(7-Chloro-quinolin-4-ylamino)-2-ethylaminomethyl...)
Affinity DataIC50:  5.40E+4nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
University Of Liverpool

Curated by ChEMBL
LigandPNGBDBM50056190(4-(7-Chloro-quinolin-4-ylamino)-2-ethylaminomethyl...)
Affinity DataIC50:  5.80E+4nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
University Of Liverpool

Curated by ChEMBL
LigandPNGBDBM50041457(4-[(7-chloroquinolin-4-yl)amino]-2-[(diethylamino)...)
Affinity DataIC50:  6.20E+4nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetCytochrome P450 2C19(Homo sapiens (Human))
University Of Liverpool

Curated by ChEMBL
LigandPNGBDBM50247629(CHEMBL453384 | N-(3-((tert-butylamino)methyl)-4-fl...)
Affinity DataIC50:  6.40E+4nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
University Of Liverpool

Curated by ChEMBL
LigandPNGBDBM50134931(5-(7-Chloro-quinolin-4-ylamino)-2-diethylaminometh...)
Affinity DataIC50:  7.50E+4nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
University Of Liverpool

Curated by ChEMBL
LigandPNGBDBM50041457(4-[(7-chloroquinolin-4-yl)amino]-2-[(diethylamino)...)
Affinity DataIC50:  8.50E+4nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
University Of Liverpool

Curated by ChEMBL
LigandPNGBDBM50056190(4-(7-Chloro-quinolin-4-ylamino)-2-ethylaminomethyl...)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of human CYP3A4 using PPR substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
University Of Liverpool

Curated by ChEMBL
LigandPNGBDBM50134931(5-(7-Chloro-quinolin-4-ylamino)-2-diethylaminometh...)
Affinity DataIC50: >1.00E+5nMAssay Description:Activation of human CYP3A4 using DEF substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
University Of Liverpool

Curated by ChEMBL
LigandPNGBDBM50247629(CHEMBL453384 | N-(3-((tert-butylamino)methyl)-4-fl...)
Affinity DataIC50: >1.00E+5nMAssay Description:Activation of human CYP3A4 using DEF substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
University Of Liverpool

Curated by ChEMBL
LigandPNGBDBM50041457(4-[(7-chloroquinolin-4-yl)amino]-2-[(diethylamino)...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human CYP3A4 using PPR substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed