Compile Data Set for Download or QSAR
maximum 50k data
Found 8 Enz. Inhib. hit(s) with all data for entry = 50028462
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Chinese Academy Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50293280(3-(4-(hydroxymethyl)phenyl)-4-(4-(methylsulfonyl)p...)
Affinity DataIC50:  14nMAssay Description:Inhibition of COX2 in mouse peritoneal macrophagesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Chinese Academy Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50293282(CHEMBL504535 | Imrecoxib)
Affinity DataIC50:  18nMAssay Description:Inhibition of COX2 in mouse peritoneal macrophagesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Mus musculus)
Chinese Academy Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50293280(3-(4-(hydroxymethyl)phenyl)-4-(4-(methylsulfonyl)p...)
Affinity DataIC50:  87nMAssay Description:Inhibition of COX1 in mouse peritoneal macrophagesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Chinese Academy Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50293280(3-(4-(hydroxymethyl)phenyl)-4-(4-(methylsulfonyl)p...)
Affinity DataIC50:  87nMAssay Description:Inhibition of LPS-induced COX2 activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Mus musculus)
Chinese Academy Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50293282(CHEMBL504535 | Imrecoxib)
Affinity DataIC50:  114nMAssay Description:Inhibition of COX1 in mouse peritoneal macrophagesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Chinese Academy Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50293281(4-(4-(4-(methylsulfonyl)phenyl)-2-oxo-1-propyl-2,5...)
Affinity DataIC50:  409nMAssay Description:Inhibition of COX2 in mouse peritoneal macrophagesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Chinese Academy Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50293281(4-(4-(4-(methylsulfonyl)phenyl)-2-oxo-1-propyl-2,5...)
Affinity DataIC50:  2.78E+3nMAssay Description:Inhibition of calcimycin-induced COX1 activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Mus musculus)
Chinese Academy Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50293281(4-(4-(4-(methylsulfonyl)phenyl)-2-oxo-1-propyl-2,5...)
Affinity DataIC50:  2.78E+3nMAssay Description:Inhibition of COX1 in mouse peritoneal macrophagesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed