Compile Data Set for Download or QSAR
maximum 50k data
Found 30 Enz. Inhib. hit(s) with all data for entry = 50028483
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50142158(5-Chloro-N-(5-chloro-pyridin-2-yl)-2-[4-(2-imino-i...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of Factor 10a (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50249295(CHEMBL471725 | N-(5-chloropyridin-2-yl)-2-(4-(N,N-...)
Affinity DataIC50:  3nMAssay Description:Inhibition of Factor 10a (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50278121(CHEMBL511643 | N-(5-chloropyridin-2-yl)-2-(4-(imin...)
Affinity DataIC50:  3nMAssay Description:Inhibition of Factor 10a (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50278729(2-(4-carbamimidoylbenzamido)-N-(5-chloropyridin-2-...)
Affinity DataIC50:  4nMAssay Description:Inhibition of Factor 10a (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50142163(5-Chloro-N-(5-chloro-pyridin-2-yl)-2-[4-(2-imino-o...)
Affinity DataIC50:  4.70nMAssay Description:Inhibition of Factor 10a (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50278806(CHEMBL496895 | N-(5-chloropyridin-2-yl)-2-(4-(N-et...)
Affinity DataIC50:  6nMAssay Description:Inhibition of Factor 10a (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50142093(2'-Sulfamoyl-biphenyl-4-carboxylic acid [2-(5-chlo...)
Affinity DataIC50:  6.70nMAssay Description:Inhibition of Factor 10a (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50278122(CHEMBL471039 | N-(5-chloropyridin-2-yl)-2-(4-(imin...)
Affinity DataIC50:  7nMAssay Description:Inhibition of Factor 10a (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50278861(CHEMBL497077 | N-(5-chloropyridin-2-yl)-2-(4-(imin...)
Affinity DataIC50:  8nMAssay Description:Inhibition of Factor 10a (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50278860(2-(4-(azetidin-1-yl(imino)methyl)benzamido)-N-(5-c...)
Affinity DataIC50:  8nMAssay Description:Inhibition of Factor 10a (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50278858(CHEMBL522407 | N-(5-chloropyridin-2-yl)-2-(4-(N-me...)
Affinity DataIC50:  9nMAssay Description:Inhibition of Factor 10a (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50278859(CHEMBL497247 | N-(5-chloropyridin-2-yl)-2-(4-(N,N-...)
Affinity DataIC50:  10nMAssay Description:Inhibition of Factor 10a (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50278123(CHEMBL471040 | N-(5-chloropyridin-2-yl)-2-(4-(imin...)
Affinity DataIC50:  12nMAssay Description:Inhibition of Factor 10a (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50278240(CHEMBL471457 | N-(5-chloropyridin-2-yl)-2-(4-(1-me...)
Affinity DataIC50:  20nMAssay Description:Inhibition of Factor 10a (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50278804(CHEMBL523081 | N-(5-chloropyridin-2-yl)-2-(4-(N-me...)
Affinity DataIC50:  23nMAssay Description:Inhibition of Factor 10a (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50278732(CHEMBL470397 | N-(5-chloropyridin-2-yl)-2-(4-(hydr...)
Affinity DataIC50:  25nMAssay Description:Inhibition of Factor 10a (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50278733(CHEMBL470398 | N-(5-chloropyridin-2-yl)-2-(4-((2,2...)
Affinity DataIC50:  30nMAssay Description:Inhibition of Factor 10a (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50278730(CHEMBL511804 | N-(5-chloropyridin-2-yl)-2-(4-(N-hy...)
Affinity DataIC50:  35nMAssay Description:Inhibition of Factor 10a (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50278159(CHEMBL511277 | N-(5-chloropyridin-2-yl)-2-(4-(imin...)
Affinity DataIC50:  38nMAssay Description:Inhibition of Factor 10a (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50278241(CHEMBL471458 | N-(5-chloropyridin-2-yl)-2-(4-(1-et...)
Affinity DataIC50:  64nMAssay Description:Inhibition of Factor 10a (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50278298(CHEMBL471874 | N-(5-chloropyridin-2-yl)-2-(4-(1-me...)
Affinity DataIC50:  78nMAssay Description:Inhibition of Factor 10a (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50278805(CHEMBL497916 | N-(5-chloropyridin-2-yl)-2-(4-(N-et...)
Affinity DataIC50:  93nMAssay Description:Inhibition of Factor 10a (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50278297(CHEMBL471670 | N-(5-chloropyridin-2-yl)-2-(4-(1,4,...)
Affinity DataIC50:  226nMAssay Description:Inhibition of Factor 10a (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50278124(CHEMBL470406 | N-{2-[(5-chloropyridin-2-yl)carbamo...)
Affinity DataIC50:  256nMAssay Description:Inhibition of Factor 10a (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50278731(CHEMBL470186 | N-(5-chloropyridin-2-yl)-2-(4-(N-me...)
Affinity DataIC50:  290nMAssay Description:Inhibition of Factor 10a (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50278239(CHEMBL512884 | N-(5-chloropyridin-2-yl)-2-(4-(4,5-...)
Affinity DataIC50:  316nMAssay Description:Inhibition of Factor 10a (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50278238(CHEMBL471456 | N-(5-chloropyridin-2-yl)-2-(4-(imin...)
Affinity DataIC50:  714nMAssay Description:Inhibition of Factor 10a (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50278729(2-(4-carbamimidoylbenzamido)-N-(5-chloropyridin-2-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of tissue plasminogen activator (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50278729(2-(4-carbamimidoylbenzamido)-N-(5-chloropyridin-2-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of thrombin (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50278729(2-(4-carbamimidoylbenzamido)-N-(5-chloropyridin-2-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of plasmin (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed