Compile Data Set for Download or QSAR
Report error Found 29 Enz. Inhib. hit(s) with all data for entry = 50028526
TargetSodium- and chloride-dependent glycine transporter 1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50277866BDBM50277866(2,4-dichloro-N-((3-(cyclopropylmethyl)-1-(1-methyl...)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of [3H]glycine uptake at human glycine transporter 1 expressed in human JAR cells after 3 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50277942BDBM50277942(2,4-dichloro-N-((3-(3-fluoropyridin-2-yl)-1-(1-met...)
Affinity DataIC50: 0.310nMAssay Description:Inhibition of [3H]glycine uptake at human glycine transporter 1 expressed in human JAR cells after 3 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50277943BDBM50277943(2,4-dichloro-N-((4-(3-fluoropyridin-2-yl)-1-(1-met...)
Affinity DataIC50: 0.650nMAssay Description:Inhibition of [3H]glycine uptake at human glycine transporter 1 expressed in human JAR cells after 3 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50277795BDBM50277795(2,4-dichloro-N-((4-(3-fluoropyridin-2-yl)-1-(1-met...)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of [3H]glycine uptake at human glycine transporter 1 expressed in human JAR cells after 3 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50278041BDBM50278041(2,4-dichloro-N-(((trans)-1-(cyclopropylmethyl)-4-(...)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of [3H]glycine uptake at human glycine transporter 1 expressed in human JAR cells after 3 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50277757BDBM50277757(2,4-dichloro-N-((1-(cyclopropylmethylsulfonyl)-4-(...)
Affinity DataIC50: 2nMAssay Description:Inhibition of [3H]glycine uptake at human glycine transporter 1 expressed in human JAR cells after 3 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50277944BDBM50277944(2,4-dichloro-N-((3-(cyclopropylmethyl)-1-(1-ethyl-...)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of [3H]glycine uptake at human glycine transporter 1 expressed in human JAR cells after 3 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50277863BDBM50277863(2,4-dichloro-N-((3-(3-fluoropyridin-2-yl)-1-(1-met...)
Affinity DataIC50: 3nMAssay Description:Inhibition of [3H]glycine uptake at human glycine transporter 1 expressed in human JAR cells after 3 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50277865BDBM50277865(2,4-dichloro-N-((3-(cyclopropylmethyl)-1-(1-methyl...)
Affinity DataIC50: 3.60nMAssay Description:Inhibition of [3H]glycine uptake at human glycine transporter 1 expressed in human JAR cells after 3 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50277756BDBM50277756(2,4-dichloro-N-((4-(3-fluoropyridin-2-yl)-1-(propy...)
Affinity DataIC50: 4.30nMAssay Description:Inhibition of [3H]glycine uptake at human glycine transporter 1 expressed in human JAR cells after 3 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50277794BDBM50277794(2,4-dichloro-N-((4-(3-fluoropyridin-2-yl)-1-(1-met...)
Affinity DataIC50: 5.40nMAssay Description:Inhibition of [3H]glycine uptake at human glycine transporter 1 expressed in human JAR cells after 3 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50278042BDBM50278042(2,4-dichloro-N-(((cis)-1-(cyclopropylmethyl)-4-(1-...)
Affinity DataIC50: 5.40nMAssay Description:Inhibition of [3H]glycine uptake at human glycine transporter 1 expressed in human JAR cells after 3 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50277864BDBM50277864(2,4-dichloro-N-((4-(cyclopropylmethyl)-1-(1-methyl...)
Affinity DataIC50: 10nMAssay Description:Inhibition of [3H]glycine uptake at human glycine transporter 1 expressed in human JAR cells after 3 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50277829BDBM50277829(2,4-dichloro-N-((4-(3-fluoropyridin-2-yl)-1-(pyrid...)
Affinity DataIC50: 12nMAssay Description:Inhibition of [3H]glycine uptake at human glycine transporter 1 expressed in human JAR cells after 3 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50277945BDBM50277945(2,4-dichloro-N-((4-(cyclopropylmethyl)-1-(1-ethyl-...)
Affinity DataIC50: 28nMAssay Description:Inhibition of [3H]glycine uptake at human glycine transporter 1 expressed in human JAR cells after 3 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50277904BDBM50277904(2,4-dichloro-N-((4-(cyclopropylmethyl)-1-(1-methyl...)
Affinity DataIC50: 32nMAssay Description:Inhibition of [3H]glycine uptake at human glycine transporter 1 expressed in human JAR cells after 3 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50277994BDBM50277994(2,4-dichloro-N-((4-(cyclopropylmethyl)-1-(4-methyl...)
Affinity DataIC50: 124nMAssay Description:Inhibition of [3H]glycine uptake at human glycine transporter 1 expressed in human JAR cells after 3 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50277796BDBM50277796(2,4-dichloro-N-((4-(3-fluoropyridin-2-yl)-1-(thiop...)
Affinity DataIC50: 125nMAssay Description:Inhibition of [3H]glycine uptake at human glycine transporter 1 expressed in human JAR cells after 3 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50277901BDBM50277901(2,4-dichloro-N-((3-(cyclopropylmethyl)-1-(2-methyl...)
Affinity DataIC50: 132nMAssay Description:Inhibition of [3H]glycine uptake at human glycine transporter 1 expressed in human JAR cells after 3 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50277902BDBM50277902(2,4-dichloro-N-((3-(cyclopropylmethyl)-1-(1-methyl...)
Affinity DataIC50: 185nMAssay Description:Inhibition of [3H]glycine uptake at human glycine transporter 1 expressed in human JAR cells after 3 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50277993BDBM50277993(2,4-dichloro-N-((4-(cyclopropylmethyl)-1-(1-methyl...)
Affinity DataIC50: 314nMAssay Description:Inhibition of [3H]glycine uptake at human glycine transporter 1 expressed in human JAR cells after 3 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50277992BDBM50277992(2,4-dichloro-N-((4-(cyclopropylmethyl)-1-(1-(2,2,2...)
Affinity DataIC50: 502nMAssay Description:Inhibition of [3H]glycine uptake at human glycine transporter 1 expressed in human JAR cells after 3 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50277903BDBM50277903(N-((1-(1H-1,2,3-triazol-4-ylsulfonyl)-3-(cycloprop...)
Affinity DataIC50: 871nMAssay Description:Inhibition of [3H]glycine uptake at human glycine transporter 1 expressed in human JAR cells after 3 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 2(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50277795BDBM50277795(2,4-dichloro-N-((4-(3-fluoropyridin-2-yl)-1-(1-met...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human glycine transporter 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 2(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50277943BDBM50277943(2,4-dichloro-N-((4-(3-fluoropyridin-2-yl)-1-(1-met...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human glycine transporter 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 2(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50277865BDBM50277865(2,4-dichloro-N-((3-(cyclopropylmethyl)-1-(1-methyl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human glycine transporter 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 2(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50277794BDBM50277794(2,4-dichloro-N-((4-(3-fluoropyridin-2-yl)-1-(1-met...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human glycine transporter 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 2(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50277904BDBM50277904(2,4-dichloro-N-((4-(cyclopropylmethyl)-1-(1-methyl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human glycine transporter 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 2(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50277864BDBM50277864(2,4-dichloro-N-((4-(cyclopropylmethyl)-1-(1-methyl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human glycine transporter 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed