Compile Data Set for Download or QSAR
maximum 50k data
Found 43 Enz. Inhib. hit(s) with all data for entry = 50028545
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50267832(1-[4-(3,4-Dihydroisoquinolin-2(1H)-yl)butyl]-1,3-d...)
Affinity DataKi:  7nMAssay Description:Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50267739(1-{(2Z)-4-[4-(1-Naphthyl)piperazin-1-yl]but-2-enyl...)
Affinity DataKi:  11.5nMAssay Description:Displacement of [3H]8-OH-DPAT from human recombinant 5HT1A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50267737(1-{5-[4-(1-Naphthyl)piperazin-1-yl]pentyl}-1,3-dih...)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]8-OH-DPAT from human recombinant 5HT1A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50267738(1-{5-[4-(1H)-benzimidazol-4-yl)piperazin-1-yl]pent...)
Affinity DataKi:  18.1nMAssay Description:Displacement of [3H]8-OH-DPAT from human recombinant 5HT1A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50267694(1-{4-[4-(1-Naphthyl)piperazin-1-yl]butyl}-1,3-dihy...)
Affinity DataKi:  22nMAssay Description:Displacement of [3H]8-OH-DPAT from human recombinant 5HT1A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50267783(1-{4-[4-(1-Naphthyl)piperazin-1-yl]but-2-ynyl}-1,3...)
Affinity DataKi:  26nMAssay Description:Displacement of [3H]8-OH-DPAT from human recombinant 5HT1A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50216042(1-(4-(4-phenyl-1-piperazinyl)butyl)indolin-2-one |...)
Affinity DataKi:  32nMAssay Description:Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50267740(1-{(2E)-4-[4-(1-Naphthyl)piperazin-1-yl]but-2-enyl...)
Affinity DataKi:  39nMAssay Description:Displacement of [3H]8-OH-DPAT from human recombinant 5HT1A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50267694(1-{4-[4-(1-Naphthyl)piperazin-1-yl]butyl}-1,3-dihy...)
Affinity DataKi:  47nMAssay Description:Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50267695(1-[5-(4-Phenylpiperazin-1-yl)pentyl]-1,3-dihydro-2...)
Affinity DataKi:  63nMAssay Description:Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50267696(1-{5-[4-(2-Methoxyphenyl)piperazin-1-yl]pentyl}-1,...)
Affinity DataKi:  63nMAssay Description:Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50267738(1-{5-[4-(1H)-benzimidazol-4-yl)piperazin-1-yl]pent...)
Affinity DataKi:  68nMAssay Description:Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50267740(1-{(2E)-4-[4-(1-Naphthyl)piperazin-1-yl]but-2-enyl...)
Affinity DataKi:  69nMAssay Description:Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50267737(1-{5-[4-(1-Naphthyl)piperazin-1-yl]pentyl}-1,3-dih...)
Affinity DataKi:  69nMAssay Description:Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50216039(1-(4-(4-(2-methoxyphenyl)-1-piperazinyl)butyl)-ind...)
Affinity DataKi:  74nMAssay Description:Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50240359(1-(5-(4-phenylpiperazin-1-yl)pentyl)benzo[cd]indol...)
Affinity DataKi:  89nMAssay Description:Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50267833(1-[3-(3,4-Dihydroisoquinolin-2(1H)-yl)propyl]-1,3-...)
Affinity DataKi:  105nMAssay Description:Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50216039(1-(4-(4-(2-methoxyphenyl)-1-piperazinyl)butyl)-ind...)
Affinity DataKi:  124nMAssay Description:Displacement of [3H]8-OH-DPAT from human recombinant 5HT1A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50216047(2-(4-(4-phenyl-1-piperazinyl)butyl)-1-isoindolinon...)
Affinity DataKi:  158nMAssay Description:Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50267786(1-[4-(4-Phenylpiperidin-1-yl)butyl]-1,3-dihydro-2H...)
Affinity DataKi:  160nMAssay Description:Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50267785(1-(4-{[4-(1-Naphthyl)piperazin-1-yl]methyl}benzyl)...)
Affinity DataKi:  181nMAssay Description:Displacement of [3H]8-OH-DPAT from human recombinant 5HT1A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50267831(1-[4-(3-Phenylpiperidin-1-yl)butyl]-1,3-dihydro-2H...)
Affinity DataKi:  193nMAssay Description:Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50267655(2-[5-(4-Phenylpiperazin-1-yl)pentyl]isoindolin-1-o...)
Affinity DataKi:  203nMAssay Description:Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50267832(1-[4-(3,4-Dihydroisoquinolin-2(1H)-yl)butyl]-1,3-d...)
Affinity DataKi:  219nMAssay Description:Displacement of [3H]8-OH-DPAT from human recombinant 5HT1A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50267739(1-{(2Z)-4-[4-(1-Naphthyl)piperazin-1-yl]but-2-enyl...)
Affinity DataKi:  250nMAssay Description:Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50267834(1-[2-(3,4-Dihydroisoquinolin-2(1H)-yl)ethyl]-1,3-d...)
Affinity DataKi:  350nMAssay Description:Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50216048(2-(4-(4-(2-methoxyphenyl)-1-piperazinyl)butyl)-1-i...)
Affinity DataKi:  360nMAssay Description:Displacement of [3H]8-OH-DPAT from human recombinant 5HT1A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50267695(1-[5-(4-Phenylpiperazin-1-yl)pentyl]-1,3-dihydro-2...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]8-OH-DPAT from human recombinant 5HT1A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50216042(1-(4-(4-phenyl-1-piperazinyl)butyl)indolin-2-one |...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]8-OH-DPAT from human recombinant 5HT1A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50267655(2-[5-(4-Phenylpiperazin-1-yl)pentyl]isoindolin-1-o...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]8-OH-DPAT from human recombinant 5HT1A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50216047(2-(4-(4-phenyl-1-piperazinyl)butyl)-1-isoindolinon...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]8-OH-DPAT from human recombinant 5HT1A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50267696(1-{5-[4-(2-Methoxyphenyl)piperazin-1-yl]pentyl}-1,...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]8-OH-DPAT from human recombinant 5HT1A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50267834(1-[2-(3,4-Dihydroisoquinolin-2(1H)-yl)ethyl]-1,3-d...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]8-OH-DPAT from human recombinant 5HT1A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50267785(1-(4-{[4-(1-Naphthyl)piperazin-1-yl]methyl}benzyl)...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50267784(1-(3-{[4-(1-Naphthyl)piperazin-1-yl]methyl}benzyl)...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50267784(1-(3-{[4-(1-Naphthyl)piperazin-1-yl]methyl}benzyl)...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]8-OH-DPAT from human recombinant 5HT1A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50267783(1-{4-[4-(1-Naphthyl)piperazin-1-yl]but-2-ynyl}-1,3...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50267786(1-[4-(4-Phenylpiperidin-1-yl)butyl]-1,3-dihydro-2H...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]8-OH-DPAT from human recombinant 5HT1A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50267831(1-[4-(3-Phenylpiperidin-1-yl)butyl]-1,3-dihydro-2H...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]8-OH-DPAT from human recombinant 5HT1A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50216048(2-(4-(4-(2-methoxyphenyl)-1-piperazinyl)butyl)-1-i...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50267833(1-[3-(3,4-Dihydroisoquinolin-2(1H)-yl)propyl]-1,3-...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]8-OH-DPAT from human recombinant 5HT1A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50267832(1-[4-(3,4-Dihydroisoquinolin-2(1H)-yl)butyl]-1,3-d...)
Affinity DataEC50:  310nMAssay Description:Agonist activity at human recombinant 5HT7 receptor expressed in CHOK1 cells assessed as increase in cAMP levels by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM10755(14C-5-hydroxy tryptamine creatinine disulfate | 2-...)
Affinity DataEC50:  15nMAssay Description:Agonist activity at human recombinant 5HT7 receptor expressed in CHOK1 cells assessed as increase in cAMP levels by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed