Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50028554
TargetCannabinoid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21278BDBM21278(SR141716 | 5-(4-chlorophenyl)-1-(2,4-dichloropheny...)
Affinity DataEC50:  240nMAssay Description:Antagonist activity at human cannabinoid CB1 receptor expressed in CHOK1 cells assessed as cAMP activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50259006BDBM50259006(1-(2,4-dichlorophenyl)-5-(5-iodothiophen-2-yl)-4-m...)
Affinity DataEC50:  320nMAssay Description:Antagonist activity at human cannabinoid CB1 receptor expressed in CHOK1 cells assessed as cAMP activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50253704BDBM50253704(5-(5-bromothiophen-2-yl)-1-(2,4-dichlorophenyl)-4-...)
Affinity DataEC50:  400nMAssay Description:Antagonist activity at human cannabinoid CB1 receptor expressed in CHOK1 cells assessed as cAMP activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50259092BDBM50259092(5-(5-bromothiophen-2-yl)-1-(2,4-dichlorophenyl)-4-...)
Affinity DataEC50:  510nMAssay Description:Antagonist activity at human cannabinoid CB1 receptor expressed in CHOK1 cells assessed as cAMP activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50259091BDBM50259091(5-(5-chlorothiophen-2-yl)-1-(2,4-dichlorophenyl)-4...)
Affinity DataEC50:  540nMAssay Description:Antagonist activity at human cannabinoid CB1 receptor expressed in CHOK1 cells assessed as cAMP activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50253755BDBM50253755(5-(5-Chlorothiophen-2-yl)-1-(2,4-dichlorophenyl)-4...)
Affinity DataEC50:  580nMAssay Description:Antagonist activity at human cannabinoid CB1 receptor expressed in CHOK1 cells assessed as cAMP activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50259048BDBM50259048(5-(5-chlorothiophen-2-yl)-1-(2,4-dichlorophenyl)-4...)
Affinity DataEC50:  690nMAssay Description:Antagonist activity at human cannabinoid CB1 receptor expressed in CHOK1 cells assessed as cAMP activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50259049BDBM50259049(5-(5-chlorothiophen-2-yl)-1-(2,4-dichlorophenyl)-N...)
Affinity DataEC50:  800nMAssay Description:Antagonist activity at human cannabinoid CB1 receptor expressed in CHOK1 cells assessed as cAMP activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50259047BDBM50259047(5-(5-chlorothiophen-2-yl)-1-(2,4-dichlorophenyl)-4...)
Affinity DataEC50:  1.00E+3nMAssay Description:Antagonist activity at human cannabinoid CB1 receptor expressed in CHOK1 cells assessed as cAMP activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50253756BDBM50253756(N-(Azepan-1-yl)-5-(5-chlorothiophen-2-yl)-1-(2,4-d...)
Affinity DataEC50:  1.10E+3nMAssay Description:Antagonist activity at human cannabinoid CB1 receptor expressed in CHOK1 cells assessed as cAMP activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50259093BDBM50259093(1-(2,4-dichlorophenyl)-4-methyl-N-(piperidin-1-yl)...)
Affinity DataEC50:  1.33E+3nMAssay Description:Antagonist activity at human cannabinoid CB1 receptor expressed in CHOK1 cells assessed as cAMP activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50259048BDBM50259048(5-(5-chlorothiophen-2-yl)-1-(2,4-dichlorophenyl)-4...)
Affinity DataEC50:  7.43E+3nMAssay Description:Antagonist activity at human cannabinoid CB2 receptor expressed in CHOK1 cells assessed as cAMP activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50259093BDBM50259093(1-(2,4-dichlorophenyl)-4-methyl-N-(piperidin-1-yl)...)
Affinity DataEC50:  7.55E+3nMAssay Description:Antagonist activity at human cannabinoid CB2 receptor expressed in CHOK1 cells assessed as cAMP activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50253756BDBM50253756(N-(Azepan-1-yl)-5-(5-chlorothiophen-2-yl)-1-(2,4-d...)
Affinity DataEC50:  1.28E+4nMAssay Description:Antagonist activity at human cannabinoid CB2 receptor expressed in CHOK1 cells assessed as cAMP activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50259049BDBM50259049(5-(5-chlorothiophen-2-yl)-1-(2,4-dichlorophenyl)-N...)
Affinity DataEC50:  1.57E+4nMAssay Description:Antagonist activity at human cannabinoid CB2 receptor expressed in CHOK1 cells assessed as cAMP activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50259092BDBM50259092(5-(5-bromothiophen-2-yl)-1-(2,4-dichlorophenyl)-4-...)
Affinity DataEC50:  1.95E+4nMAssay Description:Antagonist activity at human cannabinoid CB2 receptor expressed in CHOK1 cells assessed as cAMP activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50259047BDBM50259047(5-(5-chlorothiophen-2-yl)-1-(2,4-dichlorophenyl)-4...)
Affinity DataEC50:  2.09E+4nMAssay Description:Antagonist activity at human cannabinoid CB2 receptor expressed in CHOK1 cells assessed as cAMP activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50253704BDBM50253704(5-(5-bromothiophen-2-yl)-1-(2,4-dichlorophenyl)-4-...)
Affinity DataEC50:  2.32E+4nMAssay Description:Antagonist activity at human cannabinoid CB2 receptor expressed in CHOK1 cells assessed as cAMP activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50253755BDBM50253755(5-(5-Chlorothiophen-2-yl)-1-(2,4-dichlorophenyl)-4...)
Affinity DataEC50:  2.37E+4nMAssay Description:Antagonist activity at human cannabinoid CB2 receptor expressed in CHOK1 cells assessed as cAMP activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50259091BDBM50259091(5-(5-chlorothiophen-2-yl)-1-(2,4-dichlorophenyl)-4...)
Affinity DataEC50:  2.59E+4nMAssay Description:Antagonist activity at human cannabinoid CB2 receptor expressed in CHOK1 cells assessed as cAMP activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50259006BDBM50259006(1-(2,4-dichlorophenyl)-5-(5-iodothiophen-2-yl)-4-m...)
Affinity DataEC50:  2.94E+4nMAssay Description:Antagonist activity at human cannabinoid CB2 receptor expressed in CHOK1 cells assessed as cAMP activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21278BDBM21278(SR141716 | 5-(4-chlorophenyl)-1-(2,4-dichloropheny...)
Affinity DataEC50:  3.12E+4nMAssay Description:Antagonist activity at human cannabinoid CB2 receptor expressed in CHOK1 cells assessed as cAMP activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed