Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 3280
TargetBile acid receptor(Human)
Roche R & D Center(China)

LigandPNGBDBM30337(3-aryl isoxazole analog, 7b)
Affinity DataIC50: 45nM EC50:  102nMpH: 8.0 T: 2°CAssay Description:Binding affinity (IC50) was evaluated using scintillation proximity assay with radiolabeled ligand and biotinylated receptor. Because the scintillant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/5/2009
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Roche R & D Center(China)

LigandPNGBDBM21724(3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(p...)
Affinity DataIC50: 64nM EC50:  900nMpH: 8.0 T: 2°CAssay Description:Binding affinity (IC50) was evaluated using scintillation proximity assay with radiolabeled ligand and biotinylated receptor. Because the scintillant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/5/2009
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Roche R & D Center(China)

LigandPNGBDBM30336(3-aryl isoxazole analog, 7a)
Affinity DataIC50: 94nM EC50:  900nMpH: 8.0 T: 2°CAssay Description:Binding affinity (IC50) was evaluated using scintillation proximity assay with radiolabeled ligand and biotinylated receptor. Because the scintillant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/5/2009
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Roche R & D Center(China)

LigandPNGBDBM30334(3-aryl isoxazole analog, 6c)
Affinity DataIC50: 170nM EC50: >1.00E+4nMpH: 8.0 T: 2°CAssay Description:Binding affinity (IC50) was evaluated using scintillation proximity assay with radiolabeled ligand and biotinylated receptor. Because the scintillant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/5/2009
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Roche R & D Center(China)

LigandPNGBDBM30333(3-aryl isoxazole analog, 6b)
Affinity DataIC50: 250nM EC50:  1.00E+4nMpH: 8.0 T: 2°CAssay Description:Binding affinity (IC50) was evaluated using scintillation proximity assay with radiolabeled ligand and biotinylated receptor. Because the scintillant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/5/2009
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Roche R & D Center(China)

LigandPNGBDBM30335(CHEMBL469135 | 3-aryl isoxazole analog, 6d)
Affinity DataIC50: 690nM EC50:  9.00E+3nMpH: 8.0 T: 2°CAssay Description:Binding affinity (IC50) was evaluated using scintillation proximity assay with radiolabeled ligand and biotinylated receptor. Because the scintillant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/5/2009
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Roche R & D Center(China)

LigandPNGBDBM30342(3-aryl isoxazole analog, 7g)
Affinity DataIC50: 750nM EC50:  2.00E+3nMpH: 8.0 T: 2°CAssay Description:Binding affinity (IC50) was evaluated using scintillation proximity assay with radiolabeled ligand and biotinylated receptor. Because the scintillant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/5/2009
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Roche R & D Center(China)

LigandPNGBDBM30341(3-aryl isoxazole analog, 7f)
Affinity DataIC50: 880nM EC50:  4.00E+3nMpH: 8.0 T: 2°CAssay Description:Binding affinity (IC50) was evaluated using scintillation proximity assay with radiolabeled ligand and biotinylated receptor. Because the scintillant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/5/2009
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Roche R & D Center(China)

LigandPNGBDBM30338(3-aryl isoxazole analog, 7c)
Affinity DataIC50: 1.10E+3nM EC50:  5.00E+3nMpH: 8.0 T: 2°CAssay Description:Binding affinity (IC50) was evaluated using scintillation proximity assay with radiolabeled ligand and biotinylated receptor. Because the scintillant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/5/2009
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Roche R & D Center(China)

LigandPNGBDBM30340(3-aryl isoxazole analog, 7e)
Affinity DataIC50: 4.17E+3nM EC50:  1.20E+4nMpH: 8.0 T: 2°CAssay Description:Binding affinity (IC50) was evaluated using scintillation proximity assay with radiolabeled ligand and biotinylated receptor. Because the scintillant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/5/2009
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Roche R & D Center(China)

LigandPNGBDBM30343(3-aryl isoxazole analog, 7h)
Affinity DataIC50: 5.16E+3nM EC50: >1.00E+4nMpH: 8.0 T: 2°CAssay Description:Binding affinity (IC50) was evaluated using scintillation proximity assay with radiolabeled ligand and biotinylated receptor. Because the scintillant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/5/2009
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Roche R & D Center(China)

LigandPNGBDBM30339(3-aryl isoxazole analog, 7d)
Affinity DataIC50: 7.33E+3nM EC50:  7.00E+3nMpH: 8.0 T: 2°CAssay Description:Binding affinity (IC50) was evaluated using scintillation proximity assay with radiolabeled ligand and biotinylated receptor. Because the scintillant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/5/2009
Entry Details Article
PubMed