Compile Data Set for Download or QSAR
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Report error Found 45 Enz. Inhib. hit(s) with all data for entry = 3213
TargetCholinesterase(Human)
Csic

LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  36nMpH: 7.2 T: 22°CAssay Description:The inhibitory activity of the compounds towards BuChE was determined following the method of Ellman using BuChE from human serum and butyrylthiochol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetAcetylcholinesterase(Human)
Csic

LigandPNGBDBM29401(tacrine-dihydropyridine hybrid (tacripyrine), 12)
Affinity DataIC50:  45nMpH: 7.2 T: 22°CAssay Description:The inhibitory activity of the compounds towards hAChE was determined following the method of Ellman using AChE from human serum and acetylthiocholin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcetylcholinesterase(Electric eel)
Csic

LigandPNGBDBM29400(CHEMBL374184 | tacrine-dihydropyridine hybrid (tac...)
Affinity DataIC50:  45nMAssay Description:The inhibitory activity of the compounds towards AChE was determined following the spectrophotometric method of Rappaport using purified AChE from Ee...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcetylcholinesterase(Electric eel)
Csic

LigandPNGBDBM29402(tacrine-dihydropyridine hybrid (tacripyrine), 13)
Affinity DataIC50:  47nMAssay Description:The inhibitory activity of the compounds towards AChE was determined following the spectrophotometric method of Rappaport using purified AChE from Ee...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcetylcholinesterase(Electric eel)
Csic

LigandPNGBDBM29391(CHEMBL219172 | tacrine-dihydropyridine hybrid (tac...)
Affinity DataIC50:  52nMAssay Description:The inhibitory activity of the compounds towards AChE was determined following the spectrophotometric method of Rappaport using purified AChE from Ee...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcetylcholinesterase(Human)
Csic

LigandPNGBDBM29399(CHEMBL218940 | tacrine-dihydropyridine hybrid (tac...)
Affinity DataIC50:  58nMpH: 7.2 T: 22°CAssay Description:The inhibitory activity of the compounds towards hAChE was determined following the method of Ellman using AChE from human serum and acetylthiocholin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcetylcholinesterase(Electric eel)
Csic

LigandPNGBDBM29399(CHEMBL218940 | tacrine-dihydropyridine hybrid (tac...)
Affinity DataIC50:  61nMAssay Description:The inhibitory activity of the compounds towards AChE was determined following the spectrophotometric method of Rappaport using purified AChE from Ee...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcetylcholinesterase(Human)
Csic

LigandPNGBDBM29397(tacrine-dihydropyridine hybrid (tacripyrine), 8)
Affinity DataIC50:  71nMpH: 7.2 T: 22°CAssay Description:The inhibitory activity of the compounds towards hAChE was determined following the method of Ellman using AChE from human serum and acetylthiocholin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcetylcholinesterase(Electric eel)
Csic

LigandPNGBDBM29390(CHEMBL218939 | tacrine-dihydropyridine hybrid (tac...)
Affinity DataIC50:  80nMAssay Description:The inhibitory activity of the compounds towards AChE was determined following the spectrophotometric method of Rappaport using purified AChE from Ee...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcetylcholinesterase(Electric eel)
Csic

LigandPNGBDBM29397(tacrine-dihydropyridine hybrid (tacripyrine), 8)
Affinity DataIC50:  90nMAssay Description:The inhibitory activity of the compounds towards AChE was determined following the spectrophotometric method of Rappaport using purified AChE from Ee...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcetylcholinesterase(Electric eel)
Csic

LigandPNGBDBM29396(CHEMBL219406 | tacrine-dihydropyridine hybrid (tac...)
Affinity DataIC50:  91nMAssay Description:The inhibitory activity of the compounds towards AChE was determined following the spectrophotometric method of Rappaport using purified AChE from Ee...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcetylcholinesterase(Electric eel)
Csic

LigandPNGBDBM29401(tacrine-dihydropyridine hybrid (tacripyrine), 12)
Affinity DataIC50:  103nMAssay Description:The inhibitory activity of the compounds towards AChE was determined following the spectrophotometric method of Rappaport using purified AChE from Ee...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcetylcholinesterase(Human)
Csic

LigandPNGBDBM29400(CHEMBL374184 | tacrine-dihydropyridine hybrid (tac...)
Affinity DataIC50:  105nMpH: 7.2 T: 22°CAssay Description:The inhibitory activity of the compounds towards hAChE was determined following the method of Ellman using AChE from human serum and acetylthiocholin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcetylcholinesterase(Electric eel)
Csic

LigandPNGBDBM29394(CHEMBL220294 | tacrine-dihydropyridine hybrid (tac...)
Affinity DataIC50:  110nMAssay Description:The inhibitory activity of the compounds towards AChE was determined following the spectrophotometric method of Rappaport using purified AChE from Ee...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcetylcholinesterase(Human)
Csic

LigandPNGBDBM29390(CHEMBL218939 | tacrine-dihydropyridine hybrid (tac...)
Affinity DataIC50:  122nMpH: 7.2 T: 22°CAssay Description:The inhibitory activity of the compounds towards hAChE was determined following the method of Ellman using AChE from human serum and acetylthiocholin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcetylcholinesterase(Human)
Csic

LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  147nMpH: 7.2 T: 22°CAssay Description:The inhibitory activity of the compounds towards hAChE was determined following the method of Ellman using AChE from human serum and acetylthiocholin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetAcetylcholinesterase(Human)
Csic

LigandPNGBDBM29402(tacrine-dihydropyridine hybrid (tacripyrine), 13)
Affinity DataIC50:  158nMpH: 7.2 T: 22°CAssay Description:The inhibitory activity of the compounds towards hAChE was determined following the method of Ellman using AChE from human serum and acetylthiocholin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcetylcholinesterase(Electric eel)
Csic

LigandPNGBDBM29398(CHEMBL436302 | tacrine-dihydropyridine hybrid (tac...)
Affinity DataIC50:  160nMAssay Description:The inhibitory activity of the compounds towards AChE was determined following the spectrophotometric method of Rappaport using purified AChE from Ee...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcetylcholinesterase(Human)
Csic

LigandPNGBDBM29396(CHEMBL219406 | tacrine-dihydropyridine hybrid (tac...)
Affinity DataIC50:  169nMpH: 7.2 T: 22°CAssay Description:The inhibitory activity of the compounds towards hAChE was determined following the method of Ellman using AChE from human serum and acetylthiocholin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcetylcholinesterase(Electric eel)
Csic

LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  180nMAssay Description:The inhibitory activity of the compounds towards AChE was determined following the spectrophotometric method of Rappaport using purified AChE from Ee...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcetylcholinesterase(Human)
Csic

LigandPNGBDBM29394(CHEMBL220294 | tacrine-dihydropyridine hybrid (tac...)
Affinity DataIC50:  191nMpH: 7.2 T: 22°CAssay Description:The inhibitory activity of the compounds towards hAChE was determined following the method of Ellman using AChE from human serum and acetylthiocholin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcetylcholinesterase(Human)
Csic

LigandPNGBDBM29391(CHEMBL219172 | tacrine-dihydropyridine hybrid (tac...)
Affinity DataIC50:  193nMpH: 7.2 T: 22°CAssay Description:The inhibitory activity of the compounds towards hAChE was determined following the method of Ellman using AChE from human serum and acetylthiocholin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcetylcholinesterase(Electric eel)
Csic

LigandPNGBDBM29392(tacrine-dihydropyridine hybrid (tacripyrine), 3)
Affinity DataIC50:  210nMAssay Description:The inhibitory activity of the compounds towards AChE was determined following the spectrophotometric method of Rappaport using purified AChE from Ee...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcetylcholinesterase(Electric eel)
Csic

LigandPNGBDBM29403(tacrine-dihydropyridine hybrid (tacripyrine), 14)
Affinity DataIC50:  220nMAssay Description:The inhibitory activity of the compounds towards AChE was determined following the spectrophotometric method of Rappaport using purified AChE from Ee...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcetylcholinesterase(Human)
Csic

LigandPNGBDBM29403(tacrine-dihydropyridine hybrid (tacripyrine), 14)
Affinity DataIC50:  223nMpH: 7.2 T: 22°CAssay Description:The inhibitory activity of the compounds towards hAChE was determined following the method of Ellman using AChE from human serum and acetylthiocholin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcetylcholinesterase(Human)
Csic

LigandPNGBDBM29392(tacrine-dihydropyridine hybrid (tacripyrine), 3)
Affinity DataIC50:  226nMpH: 7.2 T: 22°CAssay Description:The inhibitory activity of the compounds towards hAChE was determined following the method of Ellman using AChE from human serum and acetylthiocholin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcetylcholinesterase(Human)
Csic

LigandPNGBDBM29398(CHEMBL436302 | tacrine-dihydropyridine hybrid (tac...)
Affinity DataIC50:  234nMpH: 7.2 T: 22°CAssay Description:The inhibitory activity of the compounds towards hAChE was determined following the method of Ellman using AChE from human serum and acetylthiocholin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcetylcholinesterase(Electric eel)
Csic

LigandPNGBDBM29393(CHEMBL219400 | tacrine-dihydropyridine hybrid (tac...)
Affinity DataIC50:  304nMAssay Description:The inhibitory activity of the compounds towards AChE was determined following the spectrophotometric method of Rappaport using purified AChE from Ee...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcetylcholinesterase(Human)
Csic

LigandPNGBDBM29395(CHEMBL219405 | tacrine-dihydropyridine hybrid (tac...)
Affinity DataIC50:  309nMpH: 7.2 T: 22°CAssay Description:The inhibitory activity of the compounds towards hAChE was determined following the method of Ellman using AChE from human serum and acetylthiocholin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcetylcholinesterase(Human)
Csic

LigandPNGBDBM29393(CHEMBL219400 | tacrine-dihydropyridine hybrid (tac...)
Affinity DataIC50:  338nMpH: 7.2 T: 22°CAssay Description:The inhibitory activity of the compounds towards hAChE was determined following the method of Ellman using AChE from human serum and acetylthiocholin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcetylcholinesterase(Electric eel)
Csic

LigandPNGBDBM29395(CHEMBL219405 | tacrine-dihydropyridine hybrid (tac...)
Affinity DataIC50:  600nMAssay Description:The inhibitory activity of the compounds towards AChE was determined following the spectrophotometric method of Rappaport using purified AChE from Ee...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCholinesterase(Human)
Csic

LigandPNGBDBM29393(CHEMBL219400 | tacrine-dihydropyridine hybrid (tac...)
Affinity DataIC50:  4.80E+3nMpH: 7.2 T: 22°CAssay Description:The inhibitory activity of the compounds towards BuChE was determined following the method of Ellman using BuChE from human serum and butyrylthiochol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCholinesterase(Human)
Csic

LigandPNGBDBM29395(CHEMBL219405 | tacrine-dihydropyridine hybrid (tac...)
Affinity DataIC50:  3.44E+4nMpH: 7.2 T: 22°CAssay Description:The inhibitory activity of the compounds towards BuChE was determined following the method of Ellman using BuChE from human serum and butyrylthiochol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCholinesterase(Human)
Csic

LigandPNGBDBM29403(tacrine-dihydropyridine hybrid (tacripyrine), 14)
Affinity DataIC50: >1.00E+5nMpH: 7.2 T: 22°CAssay Description:The inhibitory activity of the compounds towards BuChE was determined following the method of Ellman using BuChE from human serum and butyrylthiochol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCholinesterase(Human)
Csic

LigandPNGBDBM29402(tacrine-dihydropyridine hybrid (tacripyrine), 13)
Affinity DataIC50: >1.00E+5nMpH: 7.2 T: 22°CAssay Description:The inhibitory activity of the compounds towards BuChE was determined following the method of Ellman using BuChE from human serum and butyrylthiochol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCholinesterase(Human)
Csic

LigandPNGBDBM29401(tacrine-dihydropyridine hybrid (tacripyrine), 12)
Affinity DataIC50: >1.00E+5nMpH: 7.2 T: 22°CAssay Description:The inhibitory activity of the compounds towards BuChE was determined following the method of Ellman using BuChE from human serum and butyrylthiochol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCholinesterase(Human)
Csic

LigandPNGBDBM29400(CHEMBL374184 | tacrine-dihydropyridine hybrid (tac...)
Affinity DataIC50: >1.00E+5nMpH: 7.2 T: 22°CAssay Description:The inhibitory activity of the compounds towards BuChE was determined following the method of Ellman using BuChE from human serum and butyrylthiochol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCholinesterase(Human)
Csic

LigandPNGBDBM29399(CHEMBL218940 | tacrine-dihydropyridine hybrid (tac...)
Affinity DataIC50: >1.00E+5nMpH: 7.2 T: 22°CAssay Description:The inhibitory activity of the compounds towards BuChE was determined following the method of Ellman using BuChE from human serum and butyrylthiochol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCholinesterase(Human)
Csic

LigandPNGBDBM29398(CHEMBL436302 | tacrine-dihydropyridine hybrid (tac...)
Affinity DataIC50: >1.00E+5nMpH: 7.2 T: 22°CAssay Description:The inhibitory activity of the compounds towards BuChE was determined following the method of Ellman using BuChE from human serum and butyrylthiochol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCholinesterase(Human)
Csic

LigandPNGBDBM29397(tacrine-dihydropyridine hybrid (tacripyrine), 8)
Affinity DataIC50: >1.00E+5nMpH: 7.2 T: 22°CAssay Description:The inhibitory activity of the compounds towards BuChE was determined following the method of Ellman using BuChE from human serum and butyrylthiochol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCholinesterase(Human)
Csic

LigandPNGBDBM29396(CHEMBL219406 | tacrine-dihydropyridine hybrid (tac...)
Affinity DataIC50: >1.00E+5nMpH: 7.2 T: 22°CAssay Description:The inhibitory activity of the compounds towards BuChE was determined following the method of Ellman using BuChE from human serum and butyrylthiochol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCholinesterase(Human)
Csic

LigandPNGBDBM29394(CHEMBL220294 | tacrine-dihydropyridine hybrid (tac...)
Affinity DataIC50: >1.00E+5nMpH: 7.2 T: 22°CAssay Description:The inhibitory activity of the compounds towards BuChE was determined following the method of Ellman using BuChE from human serum and butyrylthiochol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCholinesterase(Human)
Csic

LigandPNGBDBM29392(tacrine-dihydropyridine hybrid (tacripyrine), 3)
Affinity DataIC50: >1.00E+5nMpH: 7.2 T: 22°CAssay Description:The inhibitory activity of the compounds towards BuChE was determined following the method of Ellman using BuChE from human serum and butyrylthiochol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCholinesterase(Human)
Csic

LigandPNGBDBM29391(CHEMBL219172 | tacrine-dihydropyridine hybrid (tac...)
Affinity DataIC50: >1.00E+5nMpH: 7.2 T: 22°CAssay Description:The inhibitory activity of the compounds towards BuChE was determined following the method of Ellman using BuChE from human serum and butyrylthiochol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCholinesterase(Human)
Csic

LigandPNGBDBM29390(CHEMBL218939 | tacrine-dihydropyridine hybrid (tac...)
Affinity DataIC50: >1.00E+5nMpH: 7.2 T: 22°CAssay Description:The inhibitory activity of the compounds towards BuChE was determined following the method of Ellman using BuChE from human serum and butyrylthiochol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed