Compile Data Set for Download or QSAR
Report error Found 82 Enz. Inhib. hit(s) with all data for entry = 50028768
TargetCaspase-7(Human)
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50258696((S)-1-[4-(Allyloxy)benzyl]-5-[1-(2-methoxymethylpy...)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of human recombinant caspase 7 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCaspase-7(Human)
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50258379((S)-5-[1-(2-Methoxymethylpyrrolidinyl)sulfonyl]-1-...)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human recombinant caspase 7 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCaspase-3(Human)
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM10320((S)-1-Methyl-5-{1-[2-(phenoxymethyl)pyrrolidinyl]s...)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of human recombinant caspase 3 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCaspase-7(Human)
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50258381((S)-5-[1-(2-Methoxymethylpyrrolidinyl)sulfonyl]-1-...)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of human recombinant caspase 7 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCaspase-3(Human)
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50258337((S)-1-(4-Fluoro-3-hydroxybutyl)-5-[1-(2-methoxymet...)
Affinity DataIC50: 3.60nMAssay Description:Inhibition of human recombinant caspase 3 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCaspase-7(Human)
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50258698((S)-1-[4-(3-Fluoro-2-hydroxypropoxy)benzyl]-5-[1-(...)
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant caspase 7 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCaspase-3(Human)
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50258379((S)-5-[1-(2-Methoxymethylpyrrolidinyl)sulfonyl]-1-...)
Affinity DataIC50: 6.60nMAssay Description:Inhibition of human recombinant caspase 3 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCaspase-7(Human)
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50258694((S)-5-[1-(2-Methoxymethylpyrrolidinyl)sulfonyl]-1-...)
Affinity DataIC50: 7.20nMAssay Description:Inhibition of human recombinant caspase 7 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCaspase-7(Human)
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50258380((S)-1-[4-(1-Fluoro-2-hydroxyethyl)benzyl]-5-[1-(2-...)
Affinity DataIC50: 7.60nMAssay Description:Inhibition of human recombinant caspase 7 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCaspase-7(Human)
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50258697((S)-5-[1-(2-Methoxymethylpyrrolidinyl)sulfonyl]-1-...)
Affinity DataIC50: 9nMAssay Description:Inhibition of human recombinant caspase 7 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCaspase-3(Human)
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50258694((S)-5-[1-(2-Methoxymethylpyrrolidinyl)sulfonyl]-1-...)
Affinity DataIC50: 9.30nMAssay Description:Inhibition of human recombinant caspase 3 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCaspase-3(Human)
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50258696((S)-1-[4-(Allyloxy)benzyl]-5-[1-(2-methoxymethylpy...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant caspase 3 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCaspase-3(Human)
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50258699((S)-1-[(S)-2,3-Dihydroxypropyl]-5-[1-(2-methoxymet...)
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant caspase 3 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCaspase-7(Human)
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50258695((S)-1-[4-(2-Bromo-1-fluoroethyl)benzyl]-5-[1-(2-me...)
Affinity DataIC50: 16nMAssay Description:Inhibition of human recombinant caspase 7 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCaspase-3(Human)
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM10318(5-{[(2S)-2-(phenoxymethyl)pyrrolidine-1-]sulfonyl}...)
Affinity DataIC50: 17nMAssay Description:Inhibition of human recombinant caspase 3 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCaspase-3(Human)
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50258697((S)-5-[1-(2-Methoxymethylpyrrolidinyl)sulfonyl]-1-...)
Affinity DataIC50: 17nMAssay Description:Inhibition of human recombinant caspase 3 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCaspase-3(Human)
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50258335((S)-1-[(S)-3-Fluoro-2-hydroxypropyl]-5-[1-(2-metho...)
Affinity DataIC50: 19nMAssay Description:Inhibition of human recombinant caspase 3 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCaspase-3(Human)
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50258378((S)-5-[1-(2-Methoxymethylpyrrolidinyl)sulfonyl]-1-...)
Affinity DataIC50: 23nMAssay Description:Inhibition of human recombinant caspase 3 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCaspase-7(Human)
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50258667((S)-1-Allyl-5-[1-(2-methoxymethylpyrrolidinyl)sulf...)
Affinity DataIC50: 24nMAssay Description:Inhibition of human recombinant caspase 7 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCaspase-3(Human)
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50258667((S)-1-Allyl-5-[1-(2-methoxymethylpyrrolidinyl)sulf...)
Affinity DataIC50: 25nMAssay Description:Inhibition of human recombinant caspase 3 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCaspase-3(Human)
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50258668((S)-1-(But-3-enyl)-5-[1-(2-methoxymethylpyrrolidin...)
Affinity DataIC50: 31nMAssay Description:Inhibition of human recombinant caspase 3 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCaspase-3(Human)
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50258381((S)-5-[1-(2-Methoxymethylpyrrolidinyl)sulfonyl]-1-...)
Affinity DataIC50: 42nMAssay Description:Inhibition of human recombinant caspase 3 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCaspase-7(Human)
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50258699((S)-1-[(S)-2,3-Dihydroxypropyl]-5-[1-(2-methoxymet...)
Affinity DataIC50: 43nMAssay Description:Inhibition of human recombinant caspase 7 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCaspase-3(Human)
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50258695((S)-1-[4-(2-Bromo-1-fluoroethyl)benzyl]-5-[1-(2-me...)
Affinity DataIC50: 43nMAssay Description:Inhibition of human recombinant caspase 3 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCaspase-7(Human)
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50258668((S)-1-(But-3-enyl)-5-[1-(2-methoxymethylpyrrolidin...)
Affinity DataIC50: 50nMAssay Description:Inhibition of human recombinant caspase 7 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCaspase-7(Human)
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50258378((S)-5-[1-(2-Methoxymethylpyrrolidinyl)sulfonyl]-1-...)
Affinity DataIC50: 61nMAssay Description:Inhibition of human recombinant caspase 7 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCaspase-7(Human)
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50258700((S)-1-(3,4-Dihydroxybutyl)-5-[1-(2-methoxymethylpy...)
Affinity DataIC50: 61nMAssay Description:Inhibition of human recombinant caspase 7 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCaspase-7(Human)
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50258336((S)-5-[1-(2-Methoxymethylpyrrolidinyl)sulfonyl]-1-...)
Affinity DataIC50: 68nMAssay Description:Inhibition of human recombinant caspase 7 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCaspase-3(Human)
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50258669((S)-5-[1-(2-Methoxymethylpyrrolidinyl)sulfonyl]-1-...)
Affinity DataIC50: 74nMAssay Description:Inhibition of human recombinant caspase 3 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCaspase-3(Human)
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50258380((S)-1-[4-(1-Fluoro-2-hydroxyethyl)benzyl]-5-[1-(2-...)
Affinity DataIC50: 80nMAssay Description:Inhibition of human recombinant caspase 3 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCaspase-3(Human)
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM10305((S)-5-[1-(2-Methoxymethyl)pyrrolidinylsulfonyl]isa...)
Affinity DataIC50: 85nMAssay Description:Inhibition of human recombinant caspase 3 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCaspase-7(Human)
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50258337((S)-1-(4-Fluoro-3-hydroxybutyl)-5-[1-(2-methoxymet...)
Affinity DataIC50: 99nMAssay Description:Inhibition of human recombinant caspase 7 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCaspase-7(Human)
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50258669((S)-5-[1-(2-Methoxymethylpyrrolidinyl)sulfonyl]-1-...)
Affinity DataIC50: 111nMAssay Description:Inhibition of human recombinant caspase 7 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCaspase-3(Human)
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50258698((S)-1-[4-(3-Fluoro-2-hydroxypropoxy)benzyl]-5-[1-(...)
Affinity DataIC50: 145nMAssay Description:Inhibition of human recombinant caspase 3 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCaspase-3(Human)
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50258336((S)-5-[1-(2-Methoxymethylpyrrolidinyl)sulfonyl]-1-...)
Affinity DataIC50: 151nMAssay Description:Inhibition of human recombinant caspase 3 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCaspase-3(Human)
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50258700((S)-1-(3,4-Dihydroxybutyl)-5-[1-(2-methoxymethylpy...)
Affinity DataIC50: 275nMAssay Description:Inhibition of human recombinant caspase 3 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCaspase-7(Human)
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM10318(5-{[(2S)-2-(phenoxymethyl)pyrrolidine-1-]sulfonyl}...)
Affinity DataIC50: 294nMAssay Description:Inhibition of human recombinant caspase 7 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCaspase-7(Human)
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM10320((S)-1-Methyl-5-{1-[2-(phenoxymethyl)pyrrolidinyl]s...)
Affinity DataIC50: 304nMAssay Description:Inhibition of human recombinant caspase 7 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCaspase-7(Human)
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50258335((S)-1-[(S)-3-Fluoro-2-hydroxypropyl]-5-[1-(2-metho...)
Affinity DataIC50: 349nMAssay Description:Inhibition of human recombinant caspase 7 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCaspase-7(Human)
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM10305((S)-5-[1-(2-Methoxymethyl)pyrrolidinylsulfonyl]isa...)
Affinity DataIC50: 1.29E+3nMAssay Description:Inhibition of human recombinant caspase 7 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCaspase-7(Human)
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50258666((S)-1-(3-Bromo-2,2-difluoropropyl)-5-[1-(2-methoxy...)
Affinity DataIC50: 1.66E+3nMAssay Description:Inhibition of human recombinant caspase 7 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCaspase-3(Human)
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50258666((S)-1-(3-Bromo-2,2-difluoropropyl)-5-[1-(2-methoxy...)
Affinity DataIC50: 1.88E+3nMAssay Description:Inhibition of human recombinant caspase 3 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCaspase-1(Human)
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50258697((S)-5-[1-(2-Methoxymethylpyrrolidinyl)sulfonyl]-1-...)
Affinity DataIC50: 3.16E+3nMAssay Description:Inhibition of human recombinant caspase 1 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCaspase-6(Human)
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50258378((S)-5-[1-(2-Methoxymethylpyrrolidinyl)sulfonyl]-1-...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of human recombinant caspase 6 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCaspase-1(Human)
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50258379((S)-5-[1-(2-Methoxymethylpyrrolidinyl)sulfonyl]-1-...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of human recombinant caspase 1 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCaspase-6(Human)
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50258379((S)-5-[1-(2-Methoxymethylpyrrolidinyl)sulfonyl]-1-...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of human recombinant caspase 6 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCaspase-1(Human)
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50258380((S)-1-[4-(1-Fluoro-2-hydroxyethyl)benzyl]-5-[1-(2-...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of human recombinant caspase 1 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCaspase-6(Human)
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50258380((S)-1-[4-(1-Fluoro-2-hydroxyethyl)benzyl]-5-[1-(2-...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of human recombinant caspase 6 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCaspase-1(Human)
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50258381((S)-5-[1-(2-Methoxymethylpyrrolidinyl)sulfonyl]-1-...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of human recombinant caspase 1 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCaspase-6(Human)
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50258381((S)-5-[1-(2-Methoxymethylpyrrolidinyl)sulfonyl]-1-...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of human recombinant caspase 6 assessed as accumulation of cleaved fluorogenic 7-amino-4-methylcoumarin after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
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