Compile Data Set for Download or QSAR
Report error Found 37 Enz. Inhib. hit(s) with all data for entry = 50028780
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268680BDBM50268680(N-3-(3-phenoxyphenyl)propylphosphonoacetamide | CH...)
Affinity DataIC50: 8nMAssay Description:Inhibition of Staphylococcus aureus histidine tagged dehydrosqualene synthase expressed in Escherichia coli BL21 (DE3) cells by continuous spectropho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268509BDBM50268509(N-[3-(3-(3,4-Dichlorophenoxy)phenyl)propyl]phospho...)
Affinity DataKi:  30nMAssay Description:Inhibition of Staphylococcus aureus histidine tagged dehydrosqualene synthase expressed in Escherichia coli BL21 (DE3) cells by continuous spectropho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268510BDBM50268510(N-[3-(3-Phenoxyphenyl)propyl]phosphonoacetamide Di...)
Affinity DataKi:  40nMAssay Description:Inhibition of Staphylococcus aureus histidine tagged dehydrosqualene synthase expressed in Escherichia coli BL21 (DE3) cells by continuous spectropho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268511BDBM50268511(N-[3-(3-(4-Chlorophenoxy)phenyl)propyl]phosphonoac...)
Affinity DataKi:  70nMAssay Description:Inhibition of Staphylococcus aureus histidine tagged dehydrosqualene synthase expressed in Escherichia coli BL21 (DE3) cells by continuous spectropho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268512BDBM50268512(3-(3-Phenoxyphenyl)propylphosphinylmethylphosphoni...)
Affinity DataKi:  220nMAssay Description:Inhibition of Staphylococcus aureus histidine tagged dehydrosqualene synthase expressed in Escherichia coli BL21 (DE3) cells by continuous spectropho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSqualene synthase(Human)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268627BDBM50268627(N-Hydroxy-2-phosphono-5-(3-phenoxyphenyl)pentamide...)
Affinity DataKi:  300nMAssay Description:Inhibition of human recombinant squalene synthase expressed in Escherichia coli cells assessed as conversion of [3H]FPP to squalene by liquid scintil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268563BDBM50268563(N-Hydroxy-N-[3-(3-phenoxyphenyl)propyl]phosphonoac...)
Affinity DataKi:  320nMAssay Description:Inhibition of Staphylococcus aureus histidine tagged dehydrosqualene synthase expressed in Escherichia coli BL21 (DE3) cells by continuous spectropho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268562BDBM50268562(N-Hydroxy-N-[3-(3-(3,4-dichlorophenoxy)phenyl)prop...)
Affinity DataKi:  320nMAssay Description:Inhibition of Staphylococcus aureus histidine tagged dehydrosqualene synthase expressed in Escherichia coli BL21 (DE3) cells by continuous spectropho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSqualene synthase(Human)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268625BDBM50268625(N-[3-(3-Phenoxyphenyl)propyl]phosphonodimethylacet...)
Affinity DataKi:  520nMAssay Description:Inhibition of human recombinant squalene synthase expressed in Escherichia coli cells assessed as conversion of [3H]FPP to squalene by liquid scintil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSqualene synthase(Human)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268510BDBM50268510(N-[3-(3-Phenoxyphenyl)propyl]phosphonoacetamide Di...)
Affinity DataKi:  530nMAssay Description:Inhibition of human recombinant squalene synthase expressed in Escherichia coli cells assessed as conversion of [3H]FPP to squalene by liquid scintil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSqualene synthase(Human)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268509BDBM50268509(N-[3-(3-(3,4-Dichlorophenoxy)phenyl)propyl]phospho...)
Affinity DataKi:  740nMAssay Description:Inhibition of human recombinant squalene synthase expressed in Escherichia coli cells assessed as conversion of [3H]FPP to squalene by liquid scintil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268565BDBM50268565(N-[3-(3-Phenoxyphenyl)propyl]sulfoacetamide | CHEM...)
Affinity DataKi:  810nMAssay Description:Inhibition of Staphylococcus aureus histidine tagged dehydrosqualene synthase expressed in Escherichia coli BL21 (DE3) cells by continuous spectropho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268564BDBM50268564(N-[3-(4-Biphenyl)propyl]phosphonoacetamide | CHEMB...)
Affinity DataKi:  810nMAssay Description:Inhibition of Staphylococcus aureus histidine tagged dehydrosqualene synthase expressed in Escherichia coli BL21 (DE3) cells by continuous spectropho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268566BDBM50268566(N-Methyl-N-[3-(3-phenoxyphenyl)propyl]phosphonoace...)
Affinity DataKi:  910nMAssay Description:Inhibition of Staphylococcus aureus histidine tagged dehydrosqualene synthase expressed in Escherichia coli BL21 (DE3) cells by continuous spectropho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268625BDBM50268625(N-[3-(3-Phenoxyphenyl)propyl]phosphonodimethylacet...)
Affinity DataKi:  960nMAssay Description:Inhibition of Staphylococcus aureus histidine tagged dehydrosqualene synthase expressed in Escherichia coli BL21 (DE3) cells by continuous spectropho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSqualene synthase(Human)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268566BDBM50268566(N-Methyl-N-[3-(3-phenoxyphenyl)propyl]phosphonoace...)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of human recombinant squalene synthase expressed in Escherichia coli cells assessed as conversion of [3H]FPP to squalene by liquid scintil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSqualene synthase(Human)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268511BDBM50268511(N-[3-(3-(4-Chlorophenoxy)phenyl)propyl]phosphonoac...)
Affinity DataKi:  1.10E+3nMAssay Description:Inhibition of human recombinant squalene synthase expressed in Escherichia coli cells assessed as conversion of [3H]FPP to squalene by liquid scintil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268626BDBM50268626(N-[2-(3-Phenoxyphenyl)ethyl]phosphonoacetamide Dip...)
Affinity DataKi:  1.50E+3nMAssay Description:Inhibition of Staphylococcus aureus histidine tagged dehydrosqualene synthase expressed in Escherichia coli BL21 (DE3) cells by continuous spectropho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSqualene synthase(Human)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268562BDBM50268562(N-Hydroxy-N-[3-(3-(3,4-dichlorophenoxy)phenyl)prop...)
Affinity DataKi:  1.60E+3nMAssay Description:Inhibition of human recombinant squalene synthase expressed in Escherichia coli cells assessed as conversion of [3H]FPP to squalene by liquid scintil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268627BDBM50268627(N-Hydroxy-2-phosphono-5-(3-phenoxyphenyl)pentamide...)
Affinity DataKi:  4.10E+3nMAssay Description:Inhibition of Staphylococcus aureus histidine tagged dehydrosqualene synthase expressed in Escherichia coli BL21 (DE3) cells by continuous spectropho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268628BDBM50268628(N-[4-(3-Phenoxyphenyl)butyl]phosphonoacetamide Dip...)
Affinity DataKi:  5.30E+3nMAssay Description:Inhibition of Staphylococcus aureus histidine tagged dehydrosqualene synthase expressed in Escherichia coli BL21 (DE3) cells by continuous spectropho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268629BDBM50268629(3-(3-Phenoxyphenyl)propyl Phosphonoacetate Dipotas...)
Affinity DataKi:  5.70E+3nMAssay Description:Inhibition of Staphylococcus aureus histidine tagged dehydrosqualene synthase expressed in Escherichia coli BL21 (DE3) cells by continuous spectropho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSqualene synthase(Human)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268626BDBM50268626(N-[2-(3-Phenoxyphenyl)ethyl]phosphonoacetamide Dip...)
Affinity DataKi:  6.20E+3nMAssay Description:Inhibition of human recombinant squalene synthase expressed in Escherichia coli cells assessed as conversion of [3H]FPP to squalene by liquid scintil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268677BDBM50268677(N-[3-(3-Phenoxyphenyl)propyl]phosphonomethylsufami...)
Affinity DataKi: >7.00E+3nMAssay Description:Inhibition of Staphylococcus aureus histidine tagged dehydrosqualene synthase expressed in Escherichia coli BL21 (DE3) cells by continuous spectropho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268676BDBM50268676(2-Oxo-6-(4-phenoxyphenyl)hexylphosphonic Acid Dipo...)
Affinity DataKi: >7.00E+3nMAssay Description:Inhibition of Staphylococcus aureus histidine tagged dehydrosqualene synthase expressed in Escherichia coli BL21 (DE3) cells by continuous spectropho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268679BDBM50268679(N-[3-(3-Phenoxyphenyl)propyl]phosphonomalonamide P...)
Affinity DataKi: >7.00E+3nMAssay Description:Inhibition of Staphylococcus aureus histidine tagged dehydrosqualene synthase expressed in Escherichia coli BL21 (DE3) cells by continuous spectropho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268678BDBM50268678(N-Hydroxy-N-[3-(4-methylbiphenyl)propyl]phosphonoa...)
Affinity DataKi: >7.00E+3nMAssay Description:Inhibition of Staphylococcus aureus histidine tagged dehydrosqualene synthase expressed in Escherichia coli BL21 (DE3) cells by continuous spectropho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSqualene synthase(Human)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268676BDBM50268676(2-Oxo-6-(4-phenoxyphenyl)hexylphosphonic Acid Dipo...)
Affinity DataKi:  2.00E+4nMAssay Description:Inhibition of human recombinant squalene synthase expressed in Escherichia coli cells assessed as conversion of [3H]FPP to squalene by liquid scintil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSqualene synthase(Human)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268563BDBM50268563(N-Hydroxy-N-[3-(3-phenoxyphenyl)propyl]phosphonoac...)
Affinity DataKi:  3.00E+4nMAssay Description:Inhibition of human recombinant squalene synthase expressed in Escherichia coli cells assessed as conversion of [3H]FPP to squalene by liquid scintil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSqualene synthase(Human)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268565BDBM50268565(N-[3-(3-Phenoxyphenyl)propyl]sulfoacetamide | CHEM...)
Affinity DataKi: >3.00E+4nMAssay Description:Inhibition of human recombinant squalene synthase expressed in Escherichia coli cells assessed as conversion of [3H]FPP to squalene by liquid scintil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSqualene synthase(Human)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268564BDBM50268564(N-[3-(4-Biphenyl)propyl]phosphonoacetamide | CHEMB...)
Affinity DataKi: >3.00E+4nMAssay Description:Inhibition of human recombinant squalene synthase expressed in Escherichia coli cells assessed as conversion of [3H]FPP to squalene by liquid scintil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSqualene synthase(Human)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268629BDBM50268629(3-(3-Phenoxyphenyl)propyl Phosphonoacetate Dipotas...)
Affinity DataKi: >3.00E+4nMAssay Description:Inhibition of human recombinant squalene synthase expressed in Escherichia coli cells assessed as conversion of [3H]FPP to squalene by liquid scintil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSqualene synthase(Human)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268628BDBM50268628(N-[4-(3-Phenoxyphenyl)butyl]phosphonoacetamide Dip...)
Affinity DataKi: >3.00E+4nMAssay Description:Inhibition of human recombinant squalene synthase expressed in Escherichia coli cells assessed as conversion of [3H]FPP to squalene by liquid scintil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSqualene synthase(Human)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268677BDBM50268677(N-[3-(3-Phenoxyphenyl)propyl]phosphonomethylsufami...)
Affinity DataKi: >3.00E+4nMAssay Description:Inhibition of human recombinant squalene synthase expressed in Escherichia coli cells assessed as conversion of [3H]FPP to squalene by liquid scintil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSqualene synthase(Human)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268679BDBM50268679(N-[3-(3-Phenoxyphenyl)propyl]phosphonomalonamide P...)
Affinity DataKi: >3.00E+4nMAssay Description:Inhibition of human recombinant squalene synthase expressed in Escherichia coli cells assessed as conversion of [3H]FPP to squalene by liquid scintil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSqualene synthase(Human)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268678BDBM50268678(N-Hydroxy-N-[3-(4-methylbiphenyl)propyl]phosphonoa...)
Affinity DataKi: >3.00E+4nMAssay Description:Inhibition of human recombinant squalene synthase expressed in Escherichia coli cells assessed as conversion of [3H]FPP to squalene by liquid scintil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSqualene synthase(Human)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268512BDBM50268512(3-(3-Phenoxyphenyl)propylphosphinylmethylphosphoni...)
Affinity DataKi: >3.00E+4nMAssay Description:Inhibition of human recombinant squalene synthase expressed in Escherichia coli cells assessed as conversion of [3H]FPP to squalene by liquid scintil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed